Application of LC-MS/MS method for the in vivo metabolite determination of oleuropein after intravenous administration to rat

Biomedical Chromatography

Volumn 25, Issue 12, 2011, Pages 1360-1363

  Zhou, Ting ^a,b   Qian, Tianxiu ^a   Wang, Xiaoying ^a   Li, Xianen ^a   Cao, Li ^a   Gui, Shuangying ^b  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b ANHUI UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

In vivo metabolite; Liquid chromatography; Oleuropein; Tandem mass spectrometry; Urine

Indexed keywords

BIOMOLECULES; BODY FLUIDS; ELECTROSPRAY IONIZATION; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; NEGATIVE IONS;

IN VIVO METABOLITE; IN-VIVO; INTRAVENOUS ADMINISTRATION; LC-MS-MS; OLEUROPEIN; RAT URINE; TANDEM MASS SPECTROMETRY; TANDEM-MASS SPECTROMETRY; URINE; VIVO METABOLITES;

RATS;

ACETIC ACID ETHYL ESTER; DRUG METABOLITE; FORMIC ACID; METHANOL; OLEUROPEIN;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; DRUG DETERMINATION; DRUG TRANSFORMATION; DRUG URINE LEVEL; ELECTROSPRAY MASS SPECTROMETRY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; OXYGENATION; QUANTITATIVE ASSAY; RAT; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 80055076180     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1609     Document Type: Article

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