Growth inhibition of human lung cancer cells via down-regulation of epidermal growth factor receptor signaling by yuanhuadine, a daphnane diterpene from Daphne genkwa

Journal of Natural Products

Volumn 74, Issue 10, 2011, Pages 2102-2108

  Hong, Ji Young ^a   Chung, Hwa Jin ^b   Lee, Hye Jung ^a   Park, Hyen Joo ^b   Lee, Sang Kook ^b  

^a Ewha Womans University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLINE; DITERPENE; EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MYC PROTEIN; PROTEIN KINASE B; PROTEIN P21; S6 KINASE; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG; YUANHUADINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CHINESE HERB; CONTROLLED STUDY; DAPHNE GENKWA; DOWN REGULATION; DRUG POTENCY; FLOWER; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LUNG NON SMALL CELL CANCER; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA, NON-SMALL-CELL LUNG; CELL CYCLE; DAPHNE; DISEASE MODELS, ANIMAL; DITERPENES; DOWN-REGULATION; FEMALE; FLOWERS; HUMANS; MICE; MICE, NUDE; MOLECULAR STRUCTURE; RECEPTOR, EPIDERMAL GROWTH FACTOR; TERPENES;

DAPHNE GENKWA; EUKARYOTA; MUS MUSCULUS;

EID: 80055067832     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np2003512     Document Type: Article

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