The interaction between the first transmembrane domain and the thumb of ASIC1a is critical for its N-Glycosylation and trafficking

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Jing, Lan ^a,b   Jiang, Yu Qing ^a,c   Jiang, Qian ^d   Wang, Bin ^e   Chu, Xiang Ping ^d   Zha, Xiang ming ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^b Shanghai Institute of Pharmaceutical Industry   (China)

^c HEBEI MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF SOUTH ALABAMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 1A; GLYCAN; MEMBRANE PROTEIN; TRANSMEMBRANE DOMAIN 1; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; ASIC CHANNEL; NERVE PROTEIN; SODIUM CHANNEL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CELL DENSITY; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DESENSITIZATION; EXTRACELLULAR MATRIX; GLYCOSYLATION; GOLGI COMPLEX; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SYNAPSE; TEMPERATURE; ANIMAL; CHEMISTRY; METABOLISM; MISSENSE MUTATION; PROTEIN TERTIARY STRUCTURE;

ANIMALS; GLYCOSYLATION; MEMBRANE PROTEINS; MICE; MUTATION, MISSENSE; NERVE TISSUE PROTEINS; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; SODIUM CHANNELS; TEMPERATURE;

EID: 80055061673     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026909     Document Type: Article

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