Heritability of ocular component dimensions in mice phenotyped using depth-enhanced swept source optical coherence tomography

Experimental Eye Research

Volumn 93, Issue 4, 2011, Pages 482-490

  Wang, Ling ^a   Považay, Boris ^a,b   Chen, Yen Po ^a,c   Hofer, Bernd ^a,b   Drexler, Wolfgang ^a,b   Guggenheim, Jeremy A ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b Christian Doppler Laboratory for Innovative Optical Imaging and its Translation to Medicine   (Austria)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Animal models; Heritability; Myopia; Ocular component dimensions; Optical coherence tomography; Refractive error

Indexed keywords

AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR EYE CHAMBER; ARTICLE; BIOMETRY; CONTROLLED STUDY; CORNEA THICKNESS; DIAGNOSTIC ACCURACY; FEMALE; GENE MAPPING; HERITABILITY; IMAGE ANALYSIS; MALE; MOUSE; NEWBORN; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; REPRODUCIBILITY; VITREOUS BODY;

ANIMALS; ANTERIOR CHAMBER; AXIAL LENGTH, EYE; BIOMETRY; CORNEA; FEMALE; LENS, CRYSTALLINE; MALE; MICE; MODELS, ANIMAL; PHENOTYPE; QUANTITATIVE TRAIT, HERITABLE; REPRODUCIBILITY OF RESULTS; TOMOGRAPHY, OPTICAL COHERENCE; VITREOUS BODY;

EID: 80055059779     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2011.06.008     Document Type: Article

References (83)

1. Alleva E., Caprioli A., Laviola G. Litter gender composition affects maternal-behavior of the primiparous mouse dam (Mus-musculus). J. Comp. Psychol. 1989, 103:83-87.
2. Almasy L., Blangero J. Multipoint quantitative-trait linkage analysis in general pedigrees. Am. J. Hum. Genet. 1998, 62:1198-1211.
3. Alsbirk P.H. Variation and heritability of ocular dimensions - population study among adult Greenland eskimos. Acta Ophthalmol. 1977, 55:443-456.
4. Atchison D.A., Smith G. Chromatic dispersions of the ocular media of human eyes. J. Opt. Soc. Am. A-Opt. Image Sci. Vis. 2005, 22:29-37.
5. Aulchenko Y.S., Ripke S., Isaacs A., Van Duijn C.M. GenABEL: an R library for genome-wide association analysis. Bioinformatics 2007, 23:1294-1296.
6. Aylor, D.L., Valdar, W., Foulds-Mathes, W., Buus, R.J., Verdugo, R.A., et al. Genetic analysis of complex traits in the emerging collaborative cross. Genome Res., in press, doi:10.1101/gr.111310.110.
7. Barathi A., Thu M.K., Beuerman R.W. Dimensional growth of the rabbit eye. Cells Tissues Organs 2002, 171:276-285.
8. Barathi V.A., Boopathi V.G., Yap E.P.H., Beuerman R.W. Two models of experimental myopia in the mouse. Vision Res. 2008, 48:904-916.
9. Barutchu A., Crewther S.G., Crewther D.P. Effects of optical defocus and spatial contrast on anterior chamber depth in chicks. Clin. Experiment. Ophthalmol. 2002, 30:217-220.
10. Biino G., Palmas M.A., Corona C., Prodi D., Fanciulli M., et al. Ocular refraction: heritability and genome-wide search for eye morphometry traits in an isolated Sardinian population. Hum. Genet. 2005, 116:152-159.
11. Bland J.M., Altman D.G. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986, 1:307-310.
12. Browman L.G. Microphthalmia and maternal effect in the white rat. Genetics 1953, 39:261-265.
13. Brown A.S., Zhang M.Y., Cucevic V., Pavlin C.J., Foster F.S. In vivo assessment of postnatal murine ocular development by ultrasound biomicroscopy. Curr. Eye Res. 2005, 30:45-51.
14. Carbonaro F., Andrew T., Mackey D.A., Young T.L., Spector T.D., et al. Repeated measures of intraocular pressure result in higher heritability and greater power in genetic linkage studies. Invest. Ophthalmol. Vis. Sci. 2009, 50:5115-5119.
15. de Castro A., Ortiz S., Gambra E., Siedlecki D., Marcos S. Three-dimensional reconstruction of the crystalline lens gradient index distribution from OCT imaging. Opt. Express. 2010, 18:21905-21917.
16. Chen C.Y., Scurrah K.J., Stankovich J., Garoufalis P., Dirani M., et al. Heritability and shared environment estimates for myopia and associated ocular biometric traits: the genes in myopia (GEM) family study. Hum. Genet. 2007, 121:511-520.
17. Chen Y.P., Prashar A., Erichsen J.T., To C.H., Hocking P.M., et al. Heritability of ocular component dimensions in chickens: genetic variants controlling susceptibility to experimentally-induced myopia and pre-treatment eye size are distinct. Invest. Ophthalmol. Vis. Sci. 2011, 52:4012-4020.
18. Cohen Y., Belkin M., Yehezkel O., Avni I., Polat U. Light intensity modulates corneal power and refraction in the chick eye exposed to continuous light. Vision Res. 2008, 48:2329-2335.
19. Dirani M., Chamberlain M., Shekar S.N., Islam A.F., Garoufalis P., et al. Heritability of refractive error and ocular biometrics: the genes in myopia (GEM) twin study. Invest. Ophthalmol. Vis. Sci. 2006, 47:4756-4761.
20. Falconer D.S., Mackay T.F.C. Introduction to Quantitative Genetics 1995, Longman, Welwyn Garden City. fourth ed.
21. Flint J., Valdar W., Shifman S., Mott R. Strategies for mapping and cloning quantitative trait genes in rodents. Nat. Rev. Genet. 2005, 6:271-286.
22. Goncharov A.V., Nowakowski M., Sheehan M.T., Dainty C. Reconstruction of the optical system of the human eye with reverse ray-tracing. Opt. Express. 2008, 16:1692-1703.
23. Guggenheim J.A., Creer R.C., Qin X.J. Postnatal refractive development in the Brown Norway rat: limitations of standard refractive and ocular component dimension measurement techniques. Curr. Eye Res. 2004, 29:369-376.
24. Gwiazda J., Thorn F., Bauer J., Held R. Emmetropization and the progression of manifest refraction in children followed from infancy to puberty. Clin. Vis. Sci. 1993, 8:337-344.
25. Hauschka T.S., Brown E. Influence of maternal age on penetrance of " eyelids open" in newborn mice. Ann. N.Y. Acad. Sci. 1954, 57:465-475.
26. Hofer B., Povazay B., Unterhuber A., Wang L., Hermann B., et al. Fast dispersion encoded full range optical coherence tomography for retinal imaging at 800 nm and 1060 nm. Opt. Express. 2010, 18:4898-4919.
27. Holmes J.M., Duffner L.A. The effect of litter size on normal retinal vascular development in the neonatal rat. Curr. Eye Res. 1995, 14:737-740.
28. Hornbeak D.M., Young T.L. Myopia genetics: a review of current research and emerging trends. Curr. Opin. Ophthalmol. 2009, 20:356-362.
29. Iraqi F.A., Churchill G., Mott R. The collaborative cross, developing a resource for mammalian systems genetics: a status report of the Wellcome Trust cohort. Mamm. Genome 2008, 19:379-381.
30. Jones C.E., Atchison D.A., Meder R., Pope J.M. Refractive index distribution and optical properties of the isolated human lens measured using magnetic resonance imaging (MRI). Vision Res. 2005, 45:2352-2366.
31. Jones L.A., Mitchell G.L., Mutti D.O., Hayes J.R., Moeschberger M.L., et al. Comparison of ocular component growth curves among refractive error groups in children. Invest. Ophthalmol. Vis. Sci. 2005, 46:2317-2327.
32. Kajic V., Povazay B., Hermann B., Hofer B., Marshall D., et al. Robust segmentation of intraretinal layers in the normal human fovea using a novel statistical model based on texture and shape analysis. Opt. Express. 2010, 18:14730-14744.
33. Kalter H. Sporadic congenital malformations of newborn inbred mice. Teratology 1968, 1:193-199.
34. Kempthorne O., Osbourne R.H. The interpretation of twin data. Am. J. Hum. Genet. 1961, 13:320-339.
35. Klein A.P., Suktitipat B., Duggal P., Lee K.E., Klein R., et al. Heritability analysis of spherical equivalent, axial length, corneal curvature, and anterior chamber depth in the Beaver dam eye study. Arch. Ophthalmol. 2009, 127:649-655.
36. Landers J.A., Hewitt A.W., Dimasi D.P., Charlesworth J.C., Straga T., et al. Heritability of central corneal thickness in nuclear families. Invest. Ophthalmol. Vis. Sci. 2009, 50:4087-4090.
37. Larsen J.S. The sagittal growth of the eye. IV. Ultrasonic measurement of the axial length of the eye from birth to puberty. Acta Ophthalmol. 1971, 49:873-886.
38. Li T., Howland H.C. Role of the pineal gland in ocular development of the chick in normal and constant light conditions. Invest. Ophthalmol. Vis. Sci. 2006, 47:5132-5136.
39. Liljander M., Sallstrom M.A., Andersson S., Wernhoff P., Andersson A., et al. Identification of genetic regions of importance for reproductive performance in female mice. Genetics 2006, 173:901-909.
40. Lively G.D., Jiang B., Hedberg-Buenz A., Chang B., Petersen G.E., et al. Genetic dependence of central corneal thickness among inbred strains of mice. Invest. Ophthalmol. Vis. Sci. 2010, 51:160-171.
41. Lively G.D., Koehn D., Hedberg-Buenz A., Wang K., Anderson M.G. Quantitative trait loci associated with murine central corneal thickness. Physiol. Genomics 2010, 42:281-286.
42. Lyhne N., Sjolie A.K., Kyvik K.O., Green A. The importance of genes and environment for ocular refraction and its determiners: a population based study among 20-45 year old twins. Br. J. Ophthalmol. 2001, 85:1470-1476.
43. Morgan I.G. The biological basis of myopic refractive error. Clin. Exp. Optom. 2003, 86:276-288.
44. Mott R., Flint J. Prospects for complex trait analysis in the mouse. Mamm. Genome 2008, 19:306-308.
45. Mott R., Talbot C.J., Turri M.G., Collins A.C., Flint J. A method for fine mapping quantitative trait loci in outbred animal stocks. Proc. Natl. Acad. Sci. U S A 2000, 97:12649-12654.
46. Norton T.T., McBrien N.A. Normal development of refractive state and ocular component dimensions in the tree shrew (Tupaia belangeri). Vision Res. 1992, 32:833-842.
47. Ortiz S., Siedlecki D., Grulkowski I., Remon L., Pascual D., et al. Optical distortion correction in optical coherence tomography for quantitative ocular anterior segment by three-dimensional imaging. Opt. Express. 2010, 18:2782-2796.
48. Paget S., Vitezica Z.G., Malecaze F., Calvas P. Heritability of refractive value and ocular biometrics. Exp. Eye Res. 2008, 86:290-295.
49. Papaioannou V.E., Mkandawire J., Biggers J.D. Development and phenotypic variability of genetically identical half mouse embryos. Development 1989, 106:817-827.
50. Pierro L.J., Spiggle J. Congenital eye defects in mouse 2. Influence of litter size, litter spacing, and suckling of offspring on risk of eye defects in C57BL mice. Teratology 1969, 2:337-343.
51. Puk O., Dalke C., Favor J., de Angelis M.H., Graw J. Variations of eye size parameters among different strains of mice. Mamm. Genome 2006, 17:851-857.
52. Robinson M.L., Holmgren A., Dewey M.J. Genetic control of ocular morphogenesis: defective lens development associated with ocular anomalies in C57BL/6 mice. Exp. Eye Res. 1993, 56:7-16.
53. Rutledge J.J., Eisen E.J., Robison O.W., Legates J.E. Dynamics of genetic and maternal effects in mice. J. Anim. Sci. 1972, 35:911.
54. Schmucker C., Schaeffel F. In vivo biometry in the mouse eye with low coherence interferometry. Vision Res. 2004, 44:2445-2456.
55. Schmucker C., Schaeffel F. A paraxial schematic eye model for the growing C57BL/6 mouse. Vision Res. 2004, 44:1857-1867.
56. Smith E.L. Environmentally induced refractive errors in animals. Myopia and Nearwork 1998, Butterworth-Heinemann, Oxford, UK. M. Rosenfield, B. Gilmartin (Eds.).
57. Smith R.S., Sundberg J.P., John S.W.M. Systematic Evaluation of the Mouse Eye: Anatomy, Pathology and Biomethods 2002, CRC Press, Boca Raton, Florida.
58. Srinivasan V.J., Ko T.H., Wojtkowski M., Carvalho M., Clermont A., et al. Noninvasive volumetric imaging and morphometry of the rodent retina with high-speed, ultrahigh-resolution optical coherence tomography. Invest. Ophthalmol. Vis. Sci. 2006, 47:5522-5528.
59. Tattersall R.J., Prashar A., Singh K.D., Tokarczuk P.F., Erichsen J.T., et al. Ex vivo magnetic resonance imaging of crystalline lens dimensions in chicken. Mol. Vis. 2010, 16:144-153.
60. Tkatchenko, A.V., Tkatchenko, T.V., 2008. High-resolution small animal MRI provides in vivo measurements of eye dimensions with high accuracy. ARVO abstract, E3593.
61. Tkatchenko T.V., Shen Y., Tkatchenko A.V. Analysis of postnatal eye development in the mouse with high-resolution small animal MRI. Invest. Ophthalmol. Vis. Sci. 2010, 51:21-27.
62. Toh T.Y., Liew S.H.M., MacKinnon J.R., Hewitt A.W., Poulsen J.L., et al. Central corneal thickness is highly heritable: the twin eye studies. Invest. Ophthalmol. Vis. Sci. 2005, 46:3718-3722.
63. Twelker J.D., Mitchell G.L., Messer D.H., Bhakta R., Jones L.A., et al. Children's ocular components and age, gender, and ethnicity. Optom. Vis. Sci. 2009, 86:918-935.
64. Vitart V., Bencic G., Hayward C., Herman J.S., Huffman J.E., et al. Heritabilities of ocular biometrical traits in 2 Croatian isolates with extended pedigrees. Invest. Ophthalmol. Vis. Sci. 2010, 51:737-743.
65. Wallman J. Parental history and myopia: taking the long view. J. Am. Med. Assoc. 1994, 272:1255-1256.
66. Wang L., Hofer B., Chen Y.-P., Guggenheim J.A., Drexler W., et al. Highly reproducible swept-source dispersion encoded full-range biometry and imaging of the mouse eye. J. Biomed. Opt. 2010, 15:046004.
67. Westenberg I.S. First detected eye-opening in albino vs. black coisogenic littermate mice. Behav. Genet. 1981, 11:281-287.
68. Westphal V., Rollins A.M., Radhakrishnan S., Izatt J.A. Correction of geometric and refractive image distortions in optical coherence tomography applying Fermat's principle. Opt. Express. 2002, 10:397-404.
69. Wisard J., Chrenek M.A., Wright C., Dalal N., Pardue M.T., et al. Non-contact measurement of linear external dimensions of the mouse eye. J. Neurosci. Methods 2010, 187:156-166.
70. Wolf J.B., Vaughn T.T., Pletscher L.S., Cheverud J.M. Contribution of maternal effect QTL to genetic architecture of early growth in mice. Heredity 2002, 89:300-310.
71. Wong H.B., Machin D., Tan S.B., Wong T.Y., Saw S.M. Ocular component growth curves among Singapore children with different refractive error status. Invest. Ophthalmol. Vis. Sci. 2010, 51:1341-1347.
72. Wright S. The relative importance of heredity and environment in determining the piebald pattern of guinea-pigs. Proc. Natl. Acad. Sci. U S A 1920, 6:320-332.
73. Yalcin B., Willis-Owen S.A.G., Fullerton J., Meesaq A., Deacon R.M., et al. Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice. Nat. Genet. 2004, 36:1197-1202.
74. Yalcin B., Nicod J., Bhomra A., Davidson S., Cleak J., et al. Commercially available outbred mice for genome-wide association studies. PLoS Genet 2010, 6. e1001131.
75. Yazbek S.N., Spiezio S.H., Nadeau J.H., Buchner D.A. Ancestral paternal genotype controls body weight and food intake for multiple generations. Hum. Mol. Genet. 2010, 19:4134-4144.
76. Young F.A., Leary G.A. The inheritance of ocular components. Am. J. Optom. 1972, 49:546-555.
77. Zadnik K. Myopia development in childhood. Optom. Vis. Sci. 1997, 74:603-608.
78. Zawadzki R.J., Leisser C., Leitget R., Pircher M., Fercher A.F. Three-dimensional ophthalmic optical coherence tomography with a refraction correction algorithm. Proc. SPIE 2003, 5140:20-27.
79. Zheng Y.F., Ge J., Huang G.F., Zhang J., Liu B., et al. Heritability of central corneal thickness in Chinese: the Guangzhou twin eye study. Invest. Ophthalmol. Vis. Sci. 2008, 49:4303-4307.
80. Zhou G., Williams R.W. Eye1 and Eye2: gene loci that modulate eye size, lens weight, and retinal area in the mouse. Invest. Ophthalmol. Vis. Sci. 1999, 40:817-825.
81. Zhou G., Williams R.W. Mouse models for the analysis of myopia: an analysis of variation in eye size of adult mice. Optom. Vis. Sci. 1999, 76:408-418.
82. Zhou X., Shen M., Xie J., Wang J., Jiang L., et al. The development of the refractive status and ocular growth in C57BL/6 mice. Invest. Ophthalmol. Vis. Sci. 2008, 49:5208-5214.
83. Zhou X., Xie J., Shen M., Wang J., Jiang L., et al. Biometric measurement of the mouse eye using optical coherence tomography with focal plane advancement. Vision Res. 2008, 48:1137-1143.