Prospects for complex trait analysis in the mouse

Mammalian Genome

Volumn 19, Issue 5, 2008, Pages 306-308

  Mott, Richard ^a   Flint, Jonathan ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENE IDENTIFICATION; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENE REPLICATION; GENETIC TRAIT; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE; HAPLOTYPE; HUMAN; INBRED STRAIN; MOUSE STRAIN; NONHUMAN; NOTE; OUTBRED STRAIN; PHENOTYPIC VARIATION; QUANTITATIVE TRAIT LOCUS; QUANTITATIVE TRAIT LOCUS MAPPING;

ANIMALS; CHROMOSOME MAPPING; GENOME; MICE; MICE, INBRED STRAINS; QUANTITATIVE TRAIT LOCI;

EID: 49249094488     PISSN: 09388990     EISSN: 14321777     Source Type: Journal    
DOI: 10.1007/s00335-008-9110-4     Document Type: Note

References (17)

1. GA Churchill DC Airey H Allayee JM Angel AD Attie 2004 The Collaborative Cross, a community resource for the genetic analysis of complex traits Nat Genet 36 1133 1137
2. V Emilsson G Thorleifsson B Zhang AS Leonardson F Zink 2008 Genetics of gene expression and its effect on disease Nature 452 423 428
3. KA Frazer E Eskin HM Kang MA Bogue DA Hinds 2007 A sequence-based variation map of 8.27 million SNPs in inbred mouse strains Nature 448 1050 1053
4. R Hitzemann B Malmanger S Cooper S Coulombe C Reed 2002 Multiple cross mapping (MCM) markedly improves the localization of a QTL for ethanol-induced activation Genes Brain Behav 1 214 222
5. CC Laurie DA Nickerson AD Anderson BS Weir RJ Livingston 2007 Linkage disequilibrium in wild mice PLoS Genet 3 e144
6. R Li MA Lyons H Wittenburg B Paigen GA Churchill 2005 Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping Genetics 169 1699 1709
7. R Mott CJ Talbot MG Turri AC Collins J Flint 2000 A method for fine mapping quantitative trait loci in outbred animal stocks Proc Natl Acad Sci USA 97 12649 12654
8. BA Payseur M Place 2007 Prospects for association mapping in classical inbred mouse strains Genetics 175 1999 2008
9. A Roberts F Pardo-Manuel de Villena W Wang L McMillan DW Threadgill 2007 The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics Mamm Genome 18 473 481
10. CA Ruivenkamp T van Wezel C Zanon AP Stassen C Vlcek 2002 Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers Nat Genet 31 295 300
11. CJ Talbot A Nicod SS Cherny DW Fulker AC Collins 1999 High-resolution mapping of quantitative trait loci in outbred mice Nat Genet 21 305 308
12. DW Threadgill KW Hunter RW Williams 2002 Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort Mamm Genome 13 175 178
13. W Valdar J Flint R Mott 2005 Simulating the collaborative cross: power of QTL detection and mapping resolution in large sets of recombinant inbred strains of mice Genetics 172 1783 1797
14. W Valdar LC Solberg D Gauguier S Burnett P Klenerman 2006 Genome-wide genetic association of complex traits in heterogeneous stock mice Nat Genet 38 879 887
15. B Yalcin SA Willis-Owen J Fullerton A Meesaq RM Deacon 2004 Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice Nat Genet 36 1197 1202
16. H Yang TA Bell GA Churchill F Pardo-Manuel de Villena 2007 On the subspecific origin of the laboratory mouse Nat Genet 39 1100 1107
17. E Zeggini LJ Scott R Saxena BF Voight JL Marchini 2008 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes Nat Genet 40 638 645