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Volumn 25, Issue 17, 2011, Pages 2069-2078

Impact of treatment with raltegravir during primary or chronic HIV infection on RNA decay characteristics and the HIV viral reservoir

Author keywords

Decay; DNA; HIV; Raltegravir; Reservoirs; RNA

Indexed keywords

EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; RALTEGRAVIR; VIRUS DNA; VIRUS RNA;

EID: 80055040631     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e32834b9658     Document Type: Article
Times cited : (67)

References (36)
  • 2
    • 0030712305 scopus 로고    scopus 로고
    • Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
    • DOI 10.1126/science.278.5341.1291
    • Wong JK, Hezareh M, Gunthard HF, Havlir DV, Ignacio CC, Spina CA, Richman DD. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science 1997; 278:1291-1295. (Pubitemid 27495741)
    • (1997) Science , vol.278 , Issue.5341 , pp. 1291-1295
    • Wong, J.K.1    Hezareh, M.2    Gunthard, H.F.3    Havlir, D.V.4    Ignacio, C.C.5    Spina, C.A.6    Richman, D.D.7
  • 12
    • 37349120701 scopus 로고    scopus 로고
    • Antiretroviral therapy with the integrase inhibitor raltegravir alters decay kinetics of HIV, significantly reducing the second phase
    • DOI 10.1097/QAD.0b013e3282f12377, PII 0000203020071112000008
    • Murray JM, Emery S, Kelleher AD, Law M, Chen J, Hazuda DJ, et al. Antiretroviral therapy with the integrase inhibitor raltegravir alters decay kinetics of HIV, significantly reducing the second phase. AIDS 2007; 21:2315-2321. (Pubitemid 350287458)
    • (2007) AIDS , vol.21 , Issue.17 , pp. 2315-2321
    • Murray, J.M.1    Emery, S.2    Kelleher, A.D.3    Law, M.4    Chen, J.5    Hazuda, D.J.6    Nguyen, B.-Y.T.7    Teppler, H.8    Cooper, D.A.9
  • 14
    • 0242499964 scopus 로고    scopus 로고
    • Longitudinal monitoring of 2-long terminal repeat circles in peripheral blood mononuclear cells from patients with chronic HIV-1 infection
    • DOI 10.1097/00002030-200303280-00001
    • Brussel A, Mathez D, Broche-Pierre S, Lancar R, Calvez T, Sonigo P, Leibowitch J. Longitudinal monitoring of 2-long terminal repeat circles in peripheral blood mononuclear cells from patients with chronic HIV-1 infection. AIDS 2003; 17:645-652. (Pubitemid 36521070)
    • (2003) AIDS , vol.17 , Issue.5 , pp. 645-652
    • Brussel, A.1    Mathez, D.2    Broche-Pierre, S.3    Lancar, R.4    Calvez, T.5    Sonigo, P.6    Leibowitch, J.7
  • 15
    • 68349139711 scopus 로고    scopus 로고
    • HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
    • Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, Yassine-Diab B, et al. HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nat Med 2009; 15:893-900.
    • (2009) Nat Med , vol.15 , pp. 893-900
    • Chomont, N.1    El-Far, M.2    Ancuta, P.3    Trautmann, L.4    Procopio, F.A.5    Yassine-Diab, B.6
  • 19
    • 1842457823 scopus 로고    scopus 로고
    • Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminalrepeat-circle junctions
    • DOI 10.1128/JVI.78.7.3210-3222.2004
    • Svarovskaia ES, Barr R, Zhang X, Pais GC, Marchand C, Pommier Y, et al. Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminalrepeat- circle junctions. J Virol 2004; 78:3210-3222. (Pubitemid 38568261)
    • (2004) Journal of Virology , vol.78 , Issue.7 , pp. 3210-3222
    • Svarovskaia, E.S.1    Barr, R.2    Zhang, X.3    Pais, G.C.G.4    Marchand, C.5    Pommier, Y.6    Burke Jr., T.R.7    Pathak, V.K.8
  • 20
    • 0036195928 scopus 로고    scopus 로고
    • Human immunodeficiency virus cDNA metabolism: Notable stability of two-long terminal repeat circles
    • DOI 10.1128/JVI.76.8.3739-3747.2002
    • Butler SL, Johnson EP, Bushman FD. Human immunodeficiency virus cDNA metabolism: notable stability of two-long terminal repeat circles. J Virol 2002; 76:3739-3747. (Pubitemid 34250538)
    • (2002) Journal of Virology , vol.76 , Issue.8 , pp. 3739-3747
    • Butler, S.L.1    Johnson, E.P.2    Bushman, F.D.3
  • 21
    • 0036200163 scopus 로고    scopus 로고
    • Intrinsic stability of episomal circles formed during human immunodeficiency virus type 1 replication
    • DOI 10.1128/JVI.76.8.4138-4144.2002
    • Pierson TC, Kieffer TL, Ruff CT, Buck C, Gange SJ, Siliciano RF. Intrinsic stability of episomal circles formed during human immunodeficiency virus type 1 replication. J Virol 2002; 76:4138-4144. (Pubitemid 34250581)
    • (2002) Journal of Virology , vol.76 , Issue.8 , pp. 4138-4144
    • Pierson, T.C.1    Kieffer, T.L.2    Ruff, C.T.3    Buck, C.4    Gange, S.J.5    Siliciano, R.F.6
  • 22
    • 16244362723 scopus 로고    scopus 로고
    • In vivo evidence for instability of episomal human immunodeficiency virus type 1 cDNA
    • DOI 10.1128/JVI.79.8.5203-5210.2005
    • Sharkey M, Triques K, Kuritzkes DR, Stevenson M. In vivo evidence for instability of episomal human immunodeficiency virus type 1 cDNA. J Virol 2005; 79:5203-5210. (Pubitemid 40464268)
    • (2005) Journal of Virology , vol.79 , Issue.8 , pp. 5203-5210
    • Sharkey, M.1    Triques, K.2    Kuritzkes, D.R.3    Stevenson, M.4
  • 24
    • 77950537810 scopus 로고    scopus 로고
    • HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects
    • Buzon MJ, Massanella M, Llibre JM, Esteve A, Dahl V, Puertas MC, et al. HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects. Nat Med 2010; 16:460-465.
    • (2010) Nat Med , vol.16 , pp. 460-465
    • Buzon, M.J.1    Massanella, M.2    Llibre, J.M.3    Esteve, A.4    Dahl, V.5    Puertas, M.C.6
  • 26
    • 9144270766 scopus 로고    scopus 로고
    • Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loads
    • DOI 10.1128/JVI.78.2.968-979.2004
    • Persaud D, Siberry GK, Ahonkhai A, Kajdas J, Monie D, Hutton N, et al.Continued production of drug-sensitive human immunodeficiency virus type 1 in children on combination antiretroviral therapy who have undetectable viral loads.J Virol 2004;78:968-979 (Pubitemid 38067618)
    • (2004) Journal of Virology , vol.78 , Issue.2 , pp. 968-979
    • Persaud, D.1    Siberry, G.K.2    Ahonkhai, A.3    Kajdas, J.4    Monie, D.5    Hutton, N.6    Watson, D.C.7    Quinn, T.C.8    Ray, S.C.9    Siliciano, R.F.10
  • 28
    • 55949083820 scopus 로고    scopus 로고
    • HIV rebounds from latently infected cells, rather than from continuing low-level replication
    • Joos B, Fischer M, Kuster H, Pillai SK, Wong JK, Böni J, et al. HIV rebounds from latently infected cells, rather than from continuing low-level replication. Proc Natl Acad Sci U S A 2008; 105:16725-16730.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 16725-16730
    • Joos, B.1    Fischer, M.2    Kuster, H.3    Pillai, S.K.4    Wong, J.K.5    Böni, J.6
  • 29
    • 67249121143 scopus 로고    scopus 로고
    • Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy
    • Dinoso JB, Kim SY, Wiegand AM, Palmer SE, Gange SJ, Cranmer L, et al. Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy. Proc Natl Acad Sci U S A 2009; 106:9403-9408.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9403-9408
    • Dinoso, J.B.1    Kim, S.Y.2    Wiegand, A.M.3    Palmer, S.E.4    Gange, S.J.5    Cranmer, L.6
  • 30
    • 77749277080 scopus 로고    scopus 로고
    • Short-course raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy
    • McMahon D, Jones J, Wiegand A, Gange SJ, Kearney M, Palmer S, et al. Short-course raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy. Clin Infect Dis 2010; 50:912-919.
    • (2010) Clin Infect Dis , vol.50 , pp. 912-919
    • McMahon, D.1    Jones, J.2    Wiegand, A.3    Gange, S.J.4    Kearney, M.5    Palmer, S.6
  • 31
    • 77956856393 scopus 로고    scopus 로고
    • The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: A randomized controlled trial
    • Gandhi RT, Zheng L, Bosch RJ, Chan ES, Margolis DM, Read S, et al. The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial. PLoS Med 2010; 7: e1000321.
    • (2010) PLoS Med , vol.7
    • Gandhi, R.T.1    Zheng, L.2    Bosch, R.J.3    Chan, E.S.4    Margolis, D.M.5    Read, S.6
  • 33
  • 35
    • 78149417719 scopus 로고    scopus 로고
    • Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy
    • Yukl SA, Gianella S, Sinclair E, Epling L, Li Q, Duan L, et al. Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy. J Infect Dis 2010; 202:1553-1561.
    • (2010) J Infect Dis , vol.202 , pp. 1553-1561
    • Yukl, S.A.1    Gianella, S.2    Sinclair, E.3    Epling, L.4    Li, Q.5    Duan, L.6
  • 36
    • 78549235738 scopus 로고    scopus 로고
    • Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: Implications for eradication
    • Chun TW, Justement JS, Murray D, Hallahan CW, Maenza J, Collier AC, et al. Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication. AIDS 2010; 24:2803-2808.
    • (2010) AIDS , vol.24 , pp. 2803-2808
    • Chun, T.W.1    Justement, J.S.2    Murray, D.3    Hallahan, C.W.4    Maenza, J.5    Collier, A.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.