Selective over-expression of endothelin-1 in endothelial cells exacerbates inner retinal edema and neuronal death in ischemic retina

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Cheung, Simon S F ^a   Leung, Justin W C ^a   Lam, Amy K M ^a   Lam, Karen S L ^a,b   Chung, Stephen S M ^a,b   Lo, Amy C Y ^a,b   Chung, Sookja K ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN 4; ENDOTHELIN 1; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; MESSENGER RNA; TIE 1 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL METABOLISM; CELL NUCLEUS; CONTROLLED STUDY; DISEASE EXACERBATION; ENDOTHELIUM CELL; HOMOZYGOTE; MALE; MOUSE; MUELLER CELL; NEUROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; RETINA EDEMA; RETINA GANGLION CELL; RETINA ISCHEMIA; RETINA NERVE CELL; THICKNESS; ANIMAL; ENZYMOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; ISCHEMIA; METABOLISM; PAPILLEDEMA; PATHOLOGY; RETINA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

MUS; MUS MUSCULUS;

ANIMALS; AQUAPORIN 4; CELL DEATH; CELL NUCLEUS; ENDOTHELIAL CELLS; ENDOTHELIN-1; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE-AMMONIA LIGASE; IMMUNOHISTOCHEMISTRY; ISCHEMIA; MALE; MICE; PAPILLEDEMA; RECEPTOR, TIE-1; RETINA; RETINAL GANGLION CELLS; RETINAL NEURONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION;

EID: 80055036396     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026184     Document Type: Article

References (33)

1. Osborne NN, Casson RJ, Wood JP, Chidlow G, Graham M, et al. (2004) Retinal ischemia: mechanisms of damage and potential therapeutic strategies. Prog Retin Eye Res 23: 91-147.
2. Bringmann A, Francke M, Pannicke T, Biedermann B, Faude F, et al. (1999) Human Muller glial cells: altered potassium channel activity in proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci 40: 3316-3323.
3. Gorovits R, Avidan N, Avisar N, Shaked I, Vardimon L, (1997) Glutamine synthetase protects against neuronal degeneration in injured retinal tissue. Proc Natl Acad Sci U S A 94: 7024-7029.
4. Inoue-Matsuhisa E, Sogo S, Mizota A, Taniai M, Takenaka H, et al. (2003) Effect of MCI-9042, a 5-HT2 receptor antagonist, on retinal ganglion cell death and retinal ischemia. Exp Eye Res 76: 445-452.
5. Lafuente MP, Villegas-Perez MP, Selles-Navarro I, Mayor-Torroglosa S, Miralles de Imperial J, et al. (2002) Retinal ganglion cell death after acute retinal ischemia is an ongoing process whose severity and duration depends on the duration of the insult. Neuroscience 109: 157-168.
6. Nucci C, Tartaglione R, Rombola L, Morrone LA, Fazzi E, et al. (2005) Neurochemical evidence to implicate elevated glutamate in the mechanisms of high intraocular pressure (IOP)-induced retinal ganglion cell death in rat. Neurotoxicology 26: 935-941.
7. Yamamoto H, Schmidt-Kastner R, Hamasaki DI, Parel JM, (2006) Complex neurodegeneration in retina following moderate ischemia induced by bilateral common carotid artery occlusion in Wistar rats. Exp Eye Res 82: 767-779.
8. Zhang Y, Cho CH, Atchaneeyasakul LO, McFarland T, Appukuttan B, et al. (2005) Activation of the mitochondrial apoptotic pathway in a rat model of central retinal artery occlusion. Invest Ophthalmol Vis Sci 46: 2133-2139.
9. Yanoff M, Fine BS, Brucker AJ, Eagle RC Jr, (1984) Pathology of human cystoid macular edema. Surv Ophthalmol 28 (Suppl): 505-511.
10. Chauhan BC, LeVatte TL, Jollimore CA, Yu PK, Reitsamer HA, et al. (2004) Model of endothelin-1-induced chronic optic neuropathy in rat. Invest Ophthalmol Vis Sci 45: 144-152.
11. Lau J, Dang M, Hockmann K, Ball AK, (2006) Effects of acute delivery of endothelin-1 on retinal ganglion cell loss in the rat. Exp Eye Res 82: 132-145.
12. Takei K, Sato T, Nonoyama T, Miyauchi T, Goto K, et al. (1993) A new model of transient complete obstruction of retinal vessels induced by endothelin-1 injection into the posterior vitreous body in rabbits. Graefes Arch Clin Exp Ophthalmol 231: 476-481.
13. Kim TW, Kang KB, Choung HK, Park KH, Kim DM, (2000) Elevated glutamate levels in the vitreous body of an in vivo model of optic nerve ischemia. Arch Ophthalmol 118: 533-536.
14. Shihara M, Hirooka Y, Hori N, Matsuo I, Tagawa T, et al. (1998) Endothelin-1 increases the neuronal activity and augments the responses to glutamate in the NTS. Am J Physiol 275: R658-665.
15. Koon HW, (2002) Role of endothelin-1 and nitric oxide on the cardiovascular function Hong Kong The University of Hong Kong.
16. Leung JW, Ho MC, Lo AC, Chung SS, Chung SK, (2004) Endothelial Cell-specific Over-expression of Endothelin- 1 Leads to More Severe Cerebral Damage following Transient Middle Cerebral Artery Occlusion. J Cardiovasc Pharmacol 44 (Suppl 1): S293-300.
17. Kaja S, Yang SH, Wei J, Fujitani K, Liu R, et al. (2003) Estrogen protects the inner retina from apoptosis and ischemia-induced loss of Vesl-1L/Homer 1c immunoreactive synaptic connections. Invest Ophthalmol Vis Sci 44: 3155-3162.
18. Koon MHW, Chung SSM, Chung SK, (2002) FASEB J 15: A482.
19. Ho MC, Lo AC, Kurihara H, Yu AC, Chung SS, et al. (2001) Endothelin-1 protects astrocytes from hypoxic/ischemic injury. FASEB J 15: 618-626.
20. Block F, Grommes C, Kosinski C, Schmidt W, Schwarz M, (1997) Retinal ischemia induced by the intraluminal suture method in rats. Neurosci Lett 232: 45-48.
21. Cheung AK, Lo AC, So KF, Chung SS, Chung SK, (2007) Gene deletion and pharmacological inhibition of aldose reductase protect against retinal ischemic injury. Exp Eye Res 85: 608-616.
22. Li SY, Fu ZJ, Ma H, Jang WC, So KF, et al. (2009) Effect of lutein on retinal neurons and oxidative stress in a model of acute retinal ischemia/reperfusion. Invest Ophthalmol Vis Sci 50: 836-843.
23. Li SY, Yang D, Yeung CM, Yu WY, Chang RC, et al. (2011) Lycium barbarum polysaccharides reduce neuronal damage, blood-retinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury. PLoS One 6: e16380.
24. Martin PM, Roon P, Van Ells TK, Ganapathy V, Smith SB, (2004) Death of retinal neurons in streptozotocin-induced diabetic mice. Invest Ophthalmol Vis Sci 45: 3330-3336.
25. Iandiev I, Pannicke T, Biedermann B, Wiedemann P, Reichenbach A, et al. (2006) Ischemia-reperfusion alters the immunolocalization of glial aquaporins in rat retina. Neurosci Lett 408: 108-112.
26. Babikian V, Wijman CA, Koleini B, Malik SN, Goyal N, et al. (2001) Retinal ischemia and embolism. Etiologies and outcomes based on a prospective study. Cerebrovasc Dis 12: 108-113.
27. Chaudhary G, Sinha K, Gupta YK, (2003) Protective effect of exogenous administration of alpha-tocopherol in middle cerebral artery occlusion model of cerebral ischemia in rats. Fundam Clin Pharmacol 17: 703-707.
28. Gartshore G, Patterson J, Macrae IM, (1997) Influence of ischemia and reperfusion on the course of brain tissue swelling and blood-brain barrier permeability in a rodent model of transient focal cerebral ischemia. Exp Neurol 147: 353-360.
29. Lo AC, Chen AY, Hung VK, Yaw LP, Fung MK, et al. (2005) Endothelin-1 over-expression leads to further water accumulation and brain edema after middle cerebral artery occlusion via aquaporin 4 expression in astrocytic end-feet. J Cereb Blood Flow Metab 25: 998-1101.
30. Matthews CC, Zielke HR, Wollack JB, Fishman PS, (2000) Enzymatic degradation protects neurons from glutamate excitotoxicity. J Neurochem 75: 1045-1052.
31. Bringmann A, Uckermann O, Pannicke T, Iandiev I, Reichenbach A, et al. (2005) Neuronal versus glial cell swelling in the ischaemic retina. Acta Ophthalmol Scand 83: 528-538.
32. Pannicke T, Uckermann O, Iandiev I, Biedermann B, Wiedemann P, et al. (2005) Altered membrane physiology in Muller glial cells after transient ischemia of the rat retina. Glia 50: 1-11.
33. Tso MO, (1982) Pathology of cystoid macular edema. Ophthalmology 89: 902-915.