Influence of ischemia and reperfusion on the course of brain tissue swelling and blood-brain barrier permeability in a rodent model of transient focal cerebral ischemia

Experimental Neurology

Volumn 147, Issue 2, 1997, Pages 353-360

  Gartshore, Gail ^a   Patterson, James ^b   Macrae, I Mhairi ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b SOUTHERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; BLOOD BRAIN BARRIER; BLOOD VESSEL PERMEABILITY; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; BRAIN PERFUSION; CONTROLLED STUDY; GENE DISRUPTION; HEAD INJURY; HYPEREMIA; MIDDLE CEREBRAL ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; STROKE;

EID: 0031257676     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1997.6635     Document Type: Article

References (34)

1. Betz A. L., Iannotti F., Hoff J. T. Brain edema: A classification based on blood-brain barrier integrity. Cerebrovasc. Brain Metab. Rev. 1:1989;133-154.
2. Betz A. L., Coester H. C. Effect of steroids on edema and sodium uptake of the brain during focal ischemia in rats. Stroke. 21:1990;1199-1204.
3. Betz A. L., Keep R. F., Beer M. E., Ren X.-d. Blood-brain barrier permeability and brain concentration of sodium, potassium, and chloride during focal ischemia. J. Cereb. Blood Flow Metab. 14:1994;29-37.
4. Blasberg R. G., Gazendam J., Patlak C. S., Fenstermacher J. D. Quantitative autoradiographic studies of brain edema and a comparison of multi-isotope autoradiographic techniques. Brain Edema. 1980;Raven, New York. p. 255-270.
5. Blasberg R. G., Laijtha A. Substrate specificity of steady state amino acid transport in mouse brain slices. Arch. Biochem. Biophys. 112:1965;361-377.
6. Blasberg R. G., Patlak C. S., Fenstermacher J. D. Selection of experimental conditions for the accurate determination of blood-brain transfer constants for single-time experiments: A theoretical analysis. J. Cereb. Blood Flow Metab. 3:1983;215-225.
7. Bounds J. V., Wiebers D. O., Whisnant J. P., Okazaki H. Mechanisms and timing of deaths from cerebral infarction. Stroke. 12:1981;474-477.
8. Dawson D. A., Graham D. I., McCulloch J., Macrae I. M. Anti-ischaemic efficacy of a nitric oxide synthase inhibitor and a N-methyl-D-aspartate receptor antagonist in models of transient and permanent focal cerebral ischaemia. Br. J. Pharmacol. 113:1994;247-253.
9. Dawson D. A., Masayasu H., Graham D. I., Macrae I. M. The neuroprotective efficacy of Ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat. Neurosci. Lett. 185:1995;1-5.
10. Ennis S. R., Keep R. F., Schielke G. P., Betz A. I. Decrease in perfusion of cerebral capillaries during incomplete ischemia and reperfusion. J. Cereb. Blood Flow Metab. 10:1990;213-220.
11. Gartshore G., Bannan P., Patterson J., Higley B., McCulloch J. Evaluation of technetium-99m exametazime stabilised with cobalt chloride as a blood flow tracer in focal cerebral ischaemia. Eur. J. Nucl. Med. 21:1994;913-923.
12. Gartshore G., Patterson J., Macrae I. M. Time course of rCBF changes and hemispheric swelling in a reperfusion model of focal cerebral ischaemia. J. Neurotrauma. 12:1995;493.
13. Gartshore G., Dawson D., Patterson J., Macrae I. M. Topographic profile of reperfusion into MCA territory following endothelin-1-induced transient focal cerebral ischaemia. Neurosci. Lett. 202:1996;209-213.
14. Hatashita S., Hoff J. T. Brain edema and cerebrovascular permeability during cerebral ischaemia in rats. Stroke. 21:1990;582-588.
15. Ishimaru S., Okada Y., Mies G., Hossmann K.-A. Relationship between blood flow and blood-brain barrier permeability of sodium and albumin in focal ischaemia of rats: A triple tracer autoradiographic study. Acta Neurochir. 120:1993;72-80.
16. Kogure K., Busto R., Scheinberg P. The role of hydrostatic pressure in ischaemic brain edema. Ann. Neurol. 9:1981;273-282.
17. Kuroiwa T., Shibutani M., Okeda R. Blood-brain barrier disruption and exacerbation of ischemic brain edema after restoration of blood flow in experimental focal cerebral ischemia. Acta. Neuropathol. 76:1988;62-70.
18. Macrae I. M., Robinson M. J., Graham D. I., Reid J. L., McCulloch J. Endothelin-1-induced reductions in cerebral blood flow: Dose dependency, time course and neuropathological consequences. J. Cereb. Blood Flow Metab. 13:1993;276-284.
19. Memezawa H., Smith M.-L., Siesjo B. K. Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats. Stroke. 23:1992;552-559.
20. Nagasawa H., Kogure K. Correlation between cerebral blood flow and histological changes in a rat model of middle cerebral artery occlusion. Stroke. 20:1989;1037-1043.
21. Ng L. K. Y., Nimmannitya J. Massive cerebral infarction with severe brain swelling: A clinicopathological study. Stroke. 1:1970;158-163.
22. Ohno K., Pettigrew K. D., Rapoport S. I. Lower limits of cerebrovascular permeability to non electrolytes in the conscious rat. Am. J. Physiol. 235:1978;H299-H307.
23. O'Brien M. D. Ischemic cerebral edema. A review. Stroke. 10:1979;623-628.
24. Olsson Y., Crowell R. M., Klatzo I. The blood-brain barrier to protein tracers in focal cerebral ischemia and infarction caused by occlusion of the middle cerebral artery. Acta Neuropathol. 18:1971;89-102.
25. Osborne K. A., Shigeno T., Balarsky A. M., Ford I., McCulloch J., Teasdale G. M., Graham D. I. Quantitative assessment of early brain damage in a rat model of focal cerebral ischaemia. J. Neurol. Neurosurg. Psychol. 50:1987;402-410.
26. Preston E., Sutherland G., Finsten A. Three openings of the blood-brain barrier produced by forebrain ischemia in the rat. Neurosci. Lett. 149:1993;75-78.
27. Robinson M. J., Macrae I. M., Todd M., Reid J. L., McCulloch J. Reduction of local cerebral blood flow to pathological levels by endothelin-1 applied to the middle cerebral artery in the rat. Neurosci. Lett. 118:1990;269-272.
28. 14. Am. J. Physiol. 234:1978;H59-H66.
29. Schielke G. P., Moises H. C., Betz A. L. Blood to brain sodium transport and interstitial fluid potassium concentration in focal ischemia in the rat. J. Cereb. Blood Flow Metab. 11:1991;466-471.
30. Schuier F. J., Hossmann K.-A. Experimental brain infarcts in cats. 2. Ischemic brain edema. Stroke. 11:1980;593-600.
31. Tamura A., Graham D. I., McCulloch J., Teasdale G. M. Focal cerebral ischaemia in the rat. 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J. Cereb. Blood Flow Metab. 1:1981;53-60.
32. Todd N. V., Picozzi P., Crockard H. A., Russell R. W. R. Reperfusion after cerebral ischaemia: influence of duration of ischaemia. Stroke. 17:1986;460-466.
33. Tyson G. W., Teasdale G. M., Graham D. I., McCulloch J. Cerebrovascular permeability following MCA occlusion in the rat. J. Neurosurg. 57:1982;186-196.
34. Yang G. Y., Betz A. L. Reperfusion-induced injury to the blood-brain barrier after middle cerebral artery occlusion in rats. Stroke. 25:1994;1658-1665.