Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: Findings from in vitro and ex vivo studies

Atherosclerosis

Volumn 219, Issue 1, 2011, Pages 141-150

  Ozasa, Hideki ^a,b   Ayaori, Makoto ^a   Iizuka, Maki ^a   Terao, Yoshio ^a,b   Uto Kondo, Harumi ^a   Yakushiji, Emi ^a   Takiguchi, Shunichi ^a   Nakaya, Kazuhiro ^a   Hisada, Tetsuya ^a   Uehara, Yoshinari ^c   Ogura, Masatsune ^a   Sasaki, Makoto ^a   Komatsu, Tomohiro ^a   Horii, Shunpei ^a   Mochizuki, Seibu ^b   Yoshimura, Michihiro ^b   Ikewaki, Katsunori ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c FUKUOKA UNIVERSITY   (Japan)

Author keywords

ABCA1; ABCG1; Cholesterol efflux; Macrophage; PPAR

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; ADENOVIRUS VECTOR; APOLIPOPROTEIN A1; CHOLESTEROL; COMPLEMENTARY DNA; DACTINOMYCIN; GENOMIC DNA; HIGH DENSITY LIPOPROTEIN; MESSENGER RNA; OXYSTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PIOGLITAZONE; PLACEBO; ROSIGLITAZONE; SMALL INTERFERING RNA; SULFOTRANSFERASE;

ADULT; ARTICLE; BIOGENESIS; CELL STRAIN HEK293; CHOLESTEROL TRANSPORT; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG EFFECT; DRUG MECHANISM; EX VIVO STUDY; EXON; GENE EXPRESSION REGULATION; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRON; MACROPHAGE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS RECOMBINANT;

ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; CHOLESTEROL; DIABETES MELLITUS, TYPE 2; HEK293 CELLS; HUMANS; HYPOGLYCEMIC AGENTS; MACROPHAGES; ORPHAN NUCLEAR RECEPTORS; PPAR GAMMA; RNA INTERFERENCE; THIAZOLIDINEDIONES;

EID: 80055016477     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2011.07.113     Document Type: Article

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