The N-terminal domain of the escherichia coli pria helicase contains both the DNA- and nucleotide-binding sites. Energetics of domain-DNA interactions and allosteric effect of the nucleotide cofactors

Biochemistry

Volumn 50, Issue 43, 2011, Pages 9167-9183

  Szymanski, Michal R ^a   Bujalowski, Paul J ^a   Jezewska, Maria J ^a   Gmyrek, Aleksandra M ^a   Bujalowski, Wlodzimierz ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC EFFECT; COFACTORS; COOPERATIVE INTERACTIONS; DIRECT INTERACTIONS; DNA AFFINITY; DNA BINDING SITE; DNA-BINDING; FUNCTIONAL INTERACTION; HELICASES; N-TERMINAL DOMAINS; NUCLEOTIDE-BINDING SITES; OH GROUP; OPEN CONFORMATION; PRIA HELICASE; SPECIFIC EFFECTS; SUBSITES; TERMINAL DOMAIN;

BINDING SITES; CONFORMATIONS; DIMERS; ESCHERICHIA COLI; NUCLEOTIDES;

DNA;

DIMER; DOUBLE STRANDED DNA; HELICASE; MONOMER; NUCLEOTIDE; SINGLE STRANDED DNA;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA BINDING; ESCHERICHIA COLI; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN DOMAIN;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; BINDING SITES; DNA HELICASES; DNA, BACTERIAL; DNA, SINGLE-STRANDED; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; NUCLEOTIDES; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS;

ESCHERICHIA COLI;

EID: 80055009974     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201100k     Document Type: Article

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