Dietary hydroxypropyl methylcellulose increases excretion of saturated and trans fats by hamsters fed fast food diets

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 20, 2011, Pages 11249-11254

  Yokoyama, Wallace ^a   Anderson, William H K ^b   Albers, David R ^b   Hong, Yun Jeong ^a   Langhorst, Marsha L ^b   Hung, Shao Ching ^b   Lin, Jiann Tsyh ^a   Young, Scott A ^b  

^a WESTERN REGIONAL RESEARCH CENTER   (United States)

^b DOW CHEMICAL COMPANY   (United States)

Author keywords

cholesterol lowering; dietary fibers; fecal lipids; hamsters; HPMC

Indexed keywords

ANIMAL BODY; ANIMAL STUDIES; BILE ACID; DIETARY FIBERS; FAST FOOD; FECAL EXCRETION; FECAL LIPIDS; HAMSTERS; HPMC; HYDROXYPROPYL METHYLCELLULOSE; LIPID CONCENTRATION; MICROCRYSTALLINE CELLULOSE; TRANS FATS; TRANS FATTY ACID;

ALCOHOLS; ANIMALS; BODY FLUIDS; LIPIDS; NUTRITION; SATURATED FATTY ACIDS; UNSATURATED FATTY ACIDS;

PHYSIOLOGY;

BILE ACID; DRUG DERIVATIVE; FATTY ACID; HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; STEROL; TRANS FATTY ACID; UNSATURATED FATTY ACID;

ANIMAL; ANIMAL DISEASE; ARTICLE; CHEMISTRY; DIET; DIETARY FIBER; FAST FOOD; FAT INTAKE; FECES; HAMSTER; MALE; SYRIAN HAMSTER;

ANIMALS; BILE ACIDS AND SALTS; CRICETINAE; DIET; DIETARY FATS; DIETARY FIBER; FAST FOODS; FATTY ACIDS; FATTY ACIDS, UNSATURATED; FECES; MALE; MESOCRICETUS; METHYLCELLULOSE; STEROLS; TRANS FATTY ACIDS;

ANIMALIA; CRICETINAE; MESOCRICETUS AURATUS;

EID: 80055002799     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf2020914     Document Type: Article

References (23)

1. Bray, G. Medical consequences of obesity J. Clin. Endocrinol. Metab. 2004, 89, 2583-2589 (Pubitemid 38766335)
2. Appel, L. J.; Sacks, F. M.; Carey, J. V.; Obarzanek, E.; Swain, J. F.; Miller, E. R.; Conlin, P. R.; Erlinger, T. P.; Rosner, B. A.; Laranio, N. M.; Charleston, J.; McCarron, P.; Bishop, L. M. Effects of protein, monounsaturated fat, and carbohydrate intake on blood pressure and serum lipids: results of the OminiHeart randomized trial J. Am. Med. Assoc. 2005, 294, 2455-2464 (Pubitemid 41627923)
3. Mozaffarian, D.; Pischon, T.; Hankinson, S. E.; Rifai, N.; Joshipura, K.; Willett, W. C.; Rimm, E. B. Dietary intake of trans fatty acids and systemic inflammation in women Am. J. Clin. Nutr. 2004, 79, 606-612 (Pubitemid 41103904)
4. Li, Z.; Maglione, M.; Tu, W.; Mojica, W.; Arterburn, D.; Shugarman, L. R.; Hilton, L.; Suttorp, M.; Solomon, V.; Shekelle, P. G.; Morton, S. C. Meta-analysis: Pharmacologic treatment of obesity Ann. Intern. Med. 2005, 142, 532-546
5. Pereria, M.; O'Reilly, E.; Augustsson, K.; Fraser, G.; Goldbourt, U. Dietary Fiber and Risk of Coronary Heart Disease: A pooled analysis of cohort studies Arch. Intern. Med. 2004, 164, 370-376 (Pubitemid 38240700)
6. Burdock, G. A. Safety assessment of hydroxypropylmethylcellulose as a food ingredient Food Chem. Toxicol. 2007, 45, 2341-2351 (Pubitemid 47600462)
7. Gallaher, D. D.; Hassel, G. A.; Lee, K.-J. Relationships between viscosity of hydroxypropyl methylcellulose and plasma cholesterol in hamsters J. Nutr. 1993, 123, 1732-1738 (Pubitemid 23317241)
8. Maki, K. C.; Davidson, M. H.; Torri, S.; Ingram, K. A.; O'Mullane, J.; Daggy, B. P.; Albrecht, H. H. High-molecular-weight hydroxypropylmethylcellulose taken with or between meals is hypocholesterolemic in adult men J. Nutr. 2000, 130, 1705-1710 (Pubitemid 30451057)
9. Maki, K. C.; Davidson, M. H.; Malik, K. C.; Albrecht, H. H.; O'Mullane, J.; Daggy, B. P. Cholesterol lowering with high-viscosity hydroxypropylmethylcellulose Am. J. Cardiol. 1999, 84, 1198-1203 (Pubitemid 29507502)
10. Hung, S.-C.; Bartley, G.; Young, S. A.; Albers, D. R.; Dielman, D. R.; Anderson, W. H. K.; Yokoyama, W. Dietary fiber improves lipid homeostasis and modulates adipocytokines in hamsters J. Diabetes 2009, 1, 194-206
11. Bartley, G. E.; Yokoyama, W. H.; Young, S. A.; Anderson, W. H. K.; Hung, S.-C.; Albers, D. R.; Langhorst, M. L.; Kim, H. Hypocholesterolemic effects of hydroxypropyl methylcellulose are mediated by altered gene expression in hepatic bile and cholesterol pathways of male hamsters J. Nutr. 2010, 140, 1-6
12. Carr, T. P.; Wood, K. J.; Hassel, C. A.; Bahl, R.; Gallaher, D. D. Raising intestinal contents viscosity leads to greater excretion of neutral steroids but not bile acids in hamsters and rats Nutr. Res. (N.Y.) 2003, 23, 91-102 (Pubitemid 36152380)
13. Hong, Y. J.; Turowski, M.; Lin, J. T.; Yokoyama, W. H. Simultaneous characterization of bile acid sterols, and determination of acylglycerides in feces from soluble cellulose-fed hamsters using HPLC with evaporative light-scattering detection and APCI-MS J. Agric. Food Chem. 2007, 55, 9750-9757 (Pubitemid 350305155)
14. Reppas, C.; Meyer, J. H.; Sirois, P. J.; Dressman, J. B. Effects of hydroxypropylmethylcellulose on gastrointestinal transit and luminal viscosity in dogs Gastroenterology 1991, 100, 1217-1233
15. Fernandez, M. L.; Wilson, T. A.; Conde, K.; Vergara-Jimenez, M.; Nicolosi, R. J. Hamsters and guinea pigs differ in their plasma lipoprotein cholesterol distribution when fed diets varying in animal protein, soluble fiber, or cholesterol content J. Nutr. 1999, 129, 1323-1332 (Pubitemid 29304981)
16. Imray, C. H. E.; Minoura, T.; Davis, A.; Radley, S.; Newbold, K. M.; Lavelle-Jones, M.; Lawson, A. M.; Baker, P. R.; Neoptolemos, J. P. Comparability of hamster with human fecal unconjugated bile acids in a model of colorectal cancer Anticancer Res. 1992, 12, 553-558
17. Reeves, P. G.; Nielsen, F. H.; Fahey, G. C. AIN-93 Purified Diets for Laboratory Rodents: Final Report of the American Institute of Nutrition Ad Hoc Writing Committee on the Reformulation of the AIN-76A Rodent Diet J. Nutr. 1993, 123, 1939-1951 (Pubitemid 23342492)
18. AOCS. Preparation of methylesters of long-chain fatty acids from sampling and analysis of commercial fats and oils. Official Method Ce; AOCS: Champaign, IL, 1997; pp 2-66.
19. Rosenheck, R. Fast food consumption and increased caloric intake: A systematic review of a trajectory towards weight gain and obesity risk Obes. Rev. 2008, 9, 535-547
20. Li, R. W.; Theriault, A. G.; Au, K.; Douglas, T. D.; Casaschi, A.; Kurowska, E. M.; Mukherjee, R. Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocytokines in fructose-induced insulin resistant hamsters Life Sci. 2006, 79, 365-373 (Pubitemid 44172805)
21. Gallaher, D.; Schneeman, B. O. Effect of dietary cellulose on site of lipid absorption Am. J. Physiol. 1985, 249, G184-G191
22. Mensink, R. P.; Zock, P. L.; Kester, A. D. M.; Katan, M. B. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: A meta-analysis of 60 controlled trials Am. J. Clin. Nutr. 2003, 77, 1146-1155 (Pubitemid 44858429)
23. Vahouny, G. V.; Satchithanandam, S.; Chen, I.; Tepper, S. A.; Kritchevsky, D.; Lightfoot, F. G.; Cassidy, M. M. Dietary fiber and intestinal adaptation: Effects on lipid absorption and lymphatic transport in the rat Am. J. Clin. Nutr. 1988, 47, 201-206 (Pubitemid 18091563)