Raising intestinal contents viscosity leads to greater excretion of neutral steroids but not bile acids in hamsters and rats

Nutrition Research

Volumn 23, Issue 1, 2003, Pages 91-102

  Carr, Timothy P ^a   Wood, Kimberly J ^b   Hassel, Craig A ^b   Bahl, Rajan ^b   Gallaher, Daniel D ^b  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Bile acids; Cholesterol; Dietary fiber; Hamsters; Hydroxypropyl methylcellulose; Rats

Indexed keywords

BILE ACID; CELLULOSE; CHOLESTANOL; CHOLESTEROL; COPROSTEROL; HYDROXYPROPYLMETHYLCELLULOSE; STEROID;

ANIMAL EXPERIMENT; ARTICLE; BILE FLOW; BILIARY EXCRETION; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CHOLESTEROL LIVER LEVEL; DIET SUPPLEMENTATION; DIETARY FIBER; DIETARY INTAKE; FECES ANALYSIS; HAMSTER; INTESTINE ABSORPTION; INTESTINE FUNCTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VISCOSITY;

CRICETINAE;

EID: 0037257633     PISSN: 02715317     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0271-5317(02)00476-1     Document Type: Article

References (38)

1. Manson JE, Tosteson H, Ridker PM, Satterfield S, Hebert P, O'Connor GT, Buring JE, Hennekens CH. The primary prevention of myocardial infarction. N Engl J Med 1992;326:1406-16.
2. Anderson JW, Deakins DA, Floore TL, Smith BM, Whitis SE. Dietary fiber and coronary heart disease. Crit Rev Food Sci Nutr 1990;28:95-147.
3. Topping DL. Dietary fibre and cholesterol metabolism. Curr Opin Lipidol 1991;2:20-3.
4. Garcia-Diez F, Garcia-Mediavilla V, Bayon JE, Gonzalez-Gallego J. Pectin feeding influences fecal bile acid excretion, hepatic bile acid and cholesterol synthesis and serum cholesterol in rats. J Nutr 1996;126: 1766-71.
5. Marlett JA, Hosig KB, Vollendorf NW, Shinnick FL, Haack VS, Story JA. Mechanism of serum cholesterol reduction by oat bran. Hepatology 1994;20:1450-7.
6. Overton PD, Furlonger N, Beety JM, Chakraborty J, Tredger JA, Morgan LM. The effect of dietary sugar-beet fibre and guar gum on lipid metabolism in Wistar rats. Br J Nutr 1994;72:385-95.
7. Story JA, Kritchevsky D. Comparison of the binding of various bile acids and bile salts in vitro by several types of fiber. J Nutr 1976;106:1292-4.
8. Vahouny GV, Tombes R, Cassidy MM, Kritchevsky D, Gallo LL. Dietary fibers. V. Binding of bile salts, phospholipids and cholesterol from mixed micelles by bile acid sequestrants and dietary fibers. Lipids 1980;15:1012-8.
9. Turley SD, Daggy BP, Dietschy JM. Cholesterol-lowering action of psyllium mucilloid in the hamster: sites and possible mechanisms of action. Metabolism 1991;40:1063-73.
10. Vahouny GV, Cassidy MM. Dietary fibers and absorption of nutrients. Proc Soc Exp Biol Med 1985;180: 432-46.
11. Eastwood MA, Morris ER. Physical properties of dietary fiber that influence physiological function: a model for polymers along the gastrointestinal tract. Am J Clin Nutr 1992;55:436-42.
12. Everson GT, Daggy BP, McKinley C, Story JA. Effects of psyllium hydrophilic mucilloid on LDL-cholesterol and bile acid synthesis in hypercholesterolemic men. J Lipid Res 1992;33:1183-92.
13. Matheson HB, Story JA. Dietary psyllium hydrocolloid and pectin increase bile acid pool size and change bile acid composition in rats. J Nutr 1994;124:1161-5.
14. Moundras C, Behr SR, Rémésy C, Demigné C. Fecal losses of sterols and bile acids induced by feeding rats guar gum are due to greater pool size and liver bile acid secretion. J Nutr 1997;127:1068-76.
15. Arjmandi BH, Ahn J, Nathani S, Reeves RD. Dietary soluble fiber and cholesterol affect serum cholesterol concentration, hepatic portal venous short-chain fatty acid concentrations and fecal sterol excretion in rats. J Nutr 1992;122:246-53.
16. Favier M-L, Bost PE, Demigné C, Rémésy C. The cholesterol-lowering effect of guar gum in rats is not accompanied by an interruption of bile acid cycling. Lipids 1998;33:765-71.
17. Gallaher DD, Locket PL, Gallaher CM. Bile acid metabolism in rats fed two levels of corn oil and brans of oat, rye, and barley and sugar beet fiber. J Nutr 1992;122:473-81.
18. Carr TP, Gallaher DD, Yang C-H, Hassel CA. Increased intestinal contents viscosity reduces cholesterol absorption efficiency in hamsters fed hydroxypropyl methylcellulose. J Nutr 1996;126:1463-9.
19. Braun WH, Ramsey JC, Gehring PJ. The lack of significant absorption of methylcellulose, viscosity 3300 cP, from the gastrointestinal tract following single and multiple oral doses to the rat. Food Cosmet Toxicol 1974;12:373-6.
20. Wright RS, Anderson JW, Bridges SR. Propionate inhibits hepatocyte lipid synthesis. Proc Soc Exp Biol Med 1990;195:26-9.
21. Dressman JB, Adair CH, Barnett JL, Berardi RR, Dunn-Kucharski VA, Jarvenpaa KM, Parr DD, Sowle CA, Swidan SZ, Tobey SW, Reppas C. High-molecular-weight hydroxypropylmethylcellulose. A cholesterol-lowering agent. Arch Intern Med 1993;153:1345-53.
22. Gallaher DD, Hassel CA, Lee K-J. Relationships between viscosity of hydroxypropyl methylcellulose and plasma cholesterol in hamsters. J Nutr 1993;123:1732-8.
23. American Institute of Nutrition. Second report of the ad hoc committee on standards for nutritional studies. J Nutr 1980;110:1726.
24. Gallaher DD, Hassel CA, Lee K-J, Gallaher CM. Viscosity and fermentability as attributes of dietary fiber responsible for the hypocholesterolemic effect. J Nutr 1993;123:244-52.
25. Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 1957;226:497-509.
26. Locket PL, Gallaher DD. An improved procedure for bile acid extraction and purification and tissue distribution in the rat. Lipids 1989;24:221-3.
27. Sheltawy MJ, Lowowsky MS. Determination of fecal bile acids by an enzymatic method. Clin Chim Acta 1975;64:127-132.
28. Duncan DB. Multiple range and multiple F tests. Biometrics 1955;11:1-42.
29. Spady DK, Dietschy JM. Sterol synthesis in vivo in 18 tissues of the squirrel monkey, guinea pig, rabbit, hamster, and rat. J Lipid Res 1983;24:303-15.
30. Jokinen MP, Clarkson TB, Prichard RW. Recent advances in molecular pathology: animal models in atherosclerosis research. Exp Mol Pathol 1985;42:1-28.
31. Cai G, Carr TP. Biliary cholesterol and bile acid excretion do not increase in hamsters fed cereal-based diets containing cholesterol. Metabolism 1999;48:400-5.
32. Chang NW, Huang PC. Effects of the ratio of polyunsaturated and monounsaturated fatty acid to saturated fatty acid on rat plasma and liver lipid concentrations. Lipids 1998;33:481-7.
33. Bartram H-P, Scheppach W, Heid C, Fabian C, Kasper H. Effect of starch malabsorption on fecal bile acids and neutral sterols in humans; possible implications for colonic carcinogenesis. Cancer Res 1991;51:4238-42.
34. Reddy BS, Watanabe K, Sheinfil A. Effect of dietary wheat bran, alfalfa, pectin and carrageenan on plasma cholesterol and fecal bile acid and neutral sterol excretion in rats. J Nutr 1980;110:1247-54.
35. Favier M-L, Moundras C, Demigné C, Rémésy C. Fermentable carbohydrates exert a more potent cholesterol-lowering effect than cholestyramine. Biochim Biophys Acta 1995;1258:115-21.
36. Gallaher CM, Munion J, Hesslink R Jr, Wise J, Gallaher DD. Cholesterol reduction by glucomannan and chitosan is mediated by changes in cholesterol absorption and bile acid and fat excretion in rats. J Nutr 2000;130:2753-9.
37. Wilson MD, Rudel LL. Review of cholesterol absorption with emphasis on dietary and biliary cholesterol. J Lipid Res 1994;35:943-55.
38. Lack L. Properties and biological significance of the ileal bile salt transport system. Environ Health Perspec 1979;33:79-90.