-
1
-
-
0035086519
-
Rational design of a potent, long-lasting form of interferon: A 40 kDa branched polyethylene glycol-conjugated interferon α-2a for the treatment of hepatitis C
-
DOI 10.1021/bc000082g
-
P. Bailon, A. Palleroni, C.A. Schaffer, C.L. Spence, W.J. Fung, J.E. Porter, G.K. Ehrlich, W. Pan, Z.X. Xu, M.W. Modi, A. Farid, W. Berthold, Rational design of a potent, long-lasting form of interferon: a 40 kDa branched polyethylene glycol-conjugated interferon alpha-2a for the treatment of hepatitis C, Bioconjug. Chem. 12 (2001) 195-202. (Pubitemid 32235471)
-
(2001)
Bioconjugate Chemistry
, vol.12
, Issue.2
, pp. 195-202
-
-
Bailon, P.1
Palleroni, A.2
Schaffer, C.A.3
Spence, C.L.4
Fung, W.-J.5
Porter, J.E.6
Ehrlich, G.K.7
Pan, W.8
Xu, Z.-X.9
Modi, M.W.10
Farid, A.11
Berthold, W.12
-
2
-
-
0037338175
-
Rational design and engineering of therapeutic proteins
-
DOI 10.1016/S1359-6446(03)02610-2, PII S1359644603026102
-
S.A. Marshall, G.A. Lazar, A.J. Chirino, J.R. Desjarlais, Rational design and engineering of therapeutic proteins, Drug Discov. Today 8 (2003) 212-221. (Pubitemid 36298676)
-
(2003)
Drug Discovery Today
, vol.8
, Issue.5
, pp. 212-221
-
-
Marshall, S.A.1
Lazar, G.A.2
Chirino, A.J.3
Desjarlais, J.R.4
-
3
-
-
0347170870
-
Chemistry and biological applications of PEG
-
J.M. Harris, S. Zalipsky (Eds.), American Chemical Society, Washington, DC
-
S. Zalipsky, J.M. Harris, Chemistry and biological applications of PEG, in: J.M. Harris, S. Zalipsky (Eds.), Poly(Ethylene Glycol) Chemistry and Biological Application, American Chemical Society, Washington, DC, 1997, pp. 1-13.
-
(1997)
Poly(Ethylene Glycol) Chemistry and Biological Application
, pp. 1-13
-
-
Zalipsky, S.1
Harris, J.M.2
-
4
-
-
3042722268
-
Protein, peptide and non-peptide drug PEGylation for therapeutic application
-
DOI 10.1517/13543776.14.6.859
-
G. Pasut, A. Guiotto, F. Veronese, Protein, peptide and non-peptide drug PEGylation for therapeutic application, Expert Opin. Ther. Pat. 14 (2004) 859- 894. (Pubitemid 38868068)
-
(2004)
Expert Opinion on Therapeutic Patents
, vol.14
, Issue.6
, pp. 859-894
-
-
Pasut, G.1
Guiotto, A.2
Veronese, F.M.3
-
6
-
-
0242585450
-
2
-
DOI 10.1021/ja021264j
-
G. Digilio, L. Barbero, C. Bracco, D. Corpillo, P. Esposito, G. Piquet, S. Traversa, S. Aime, NMR structure of two novel polyethylene glycol conjugates of the human growth hormone-releasing factor, hGRF(1-29)-NH2, J. Am. Chem. Soc. 125 (2003) 3458-3470. (Pubitemid 36512420)
-
(2003)
Journal of the American Chemical Society
, vol.125
, Issue.12
, pp. 3458-3470
-
-
Digilio, G.1
Barbero, L.2
Bracco, C.3
Corpillo, D.4
Esposito, P.5
Piquet, G.6
Traversa, S.7
Aime, S.8
-
7
-
-
0037124501
-
Effects of PEG conjugation on insulin properties
-
DOI 10.1016/S0169-409X(02)00025-X, PII S0169409X0200025X
-
K.D. Hinds, S.W. Kim, Effects of PEG conjugation on insulin properties, Adv. Drug Deliv. Rev. 54 (2002) 505-530. (Pubitemid 34615546)
-
(2002)
Advanced Drug Delivery Reviews
, vol.54
, Issue.4
, pp. 505-530
-
-
Hinds, K.D.1
Kim, S.W.2
-
8
-
-
47749100432
-
PEGylation of human serum albumin: Reaction of PEG-phenyl-isothiocyanate with protein
-
DOI 10.1021/bc7003878
-
F. Meng, B.N. Manjula, P.K. Smith, S.A. Acharya, PEGylation of human serum albumin: reaction of PEG-phenyl-isothiocyanate with protein, Bioconjug. Chem. 19 (2008) 1352-1360. (Pubitemid 352032333)
-
(2008)
Bioconjugate Chemistry
, vol.19
, Issue.7
, pp. 1352-1360
-
-
Meng, F.1
Manjula, B.N.2
Smith, P.K.3
Acharya, S.A.4
-
9
-
-
18844427853
-
α2a and its individual positional isomers
-
DOI 10.1021/bc049781+
-
C. Dhalluin, A. Ross, L.A. Leuthold, S. Foser, B. Gsell, F. Muller, H. Senn, Structural and biophysical characterization of the 40 kDa PEG-interferonalpha( 2a) and its individual positional isomers, Bioconjug. Chem. 16 (2005) 504-517. (Pubitemid 40696041)
-
(2005)
Bioconjugate Chemistry
, vol.16
, Issue.3
, pp. 504-517
-
-
Dhalluin, C.1
Ross, A.2
Leuthold, L.-A.3
Foser, S.4
Gsell, B.5
Muller, F.6
Senn, H.7
-
10
-
-
26944452043
-
PEGylation, successful approach to drug delivery
-
DOI 10.1016/S1359-6446(05)03575-0, PII S1359644605035750
-
F.M. Veronese, G. Pasut, PEGylation, successful approach to drug delivery, Drug Discov. Today 10 (2005) 1451-1458. (Pubitemid 41483874)
-
(2005)
Drug Discovery Today
, vol.10
, Issue.21
, pp. 1451-1458
-
-
Veronese, F.M.1
Pasut, G.2
-
11
-
-
0037362655
-
Effect of pegylation on pharmaceuticals
-
DOI 10.1038/nrd1033
-
J.M. Harris, R.B. Chess, Effect of pegylation on pharmaceuticals, Nat. Rev. Drug Discov. 2 (2003) 214-221. (Pubitemid 37361666)
-
(2003)
Nature Reviews Drug Discovery
, vol.2
, Issue.3
, pp. 214-221
-
-
Milton Harris, J.1
Chess, R.B.2
-
12
-
-
0017329683
-
Serum-albumin - Recent progress in understanding of its structure and biosynthesis
-
T. Peters, Serum-albumin - recent progress in understanding of its structure and biosynthesis, Clin. Chem. 23 (1977) 5-12.
-
(1977)
Clin. Chem.
, vol.23
, pp. 5-12
-
-
Peters, T.1
-
13
-
-
33947502313
-
Comparison of strong anion-exchangers for the purification of a PEGylated protein
-
DOI 10.1016/j.chroma.2007.02.051, PII S0021967307003317
-
T.M. Pabst, J.J. Buckley, A.K. Hunter, Comparison of strong anion-exchangers for the purification of a PEGylated protein, J. Chromatogr. A 1147 (2007) 172- 182. (Pubitemid 46466833)
-
(2007)
Journal of Chromatography A
, vol.1147
, Issue.2
, pp. 172-182
-
-
Pabst, T.M.1
Buckley, J.J.2
Ramasubramanyan, N.3
Hunter, A.K.4
-
14
-
-
33846186433
-
Characterisation and physical stability of PEGylated glucagon
-
DOI 10.1016/j.ijpharm.2006.09.002, PII S0378517306007356
-
P. Stigsnaes, S. Frokjaer, S. Bjerregaard, M. van de Weert, P. Kingshott, E.H. Moeller, Characterisation and physical stability of PEGylated glucagon, Int. J. Pharm. 330 (2007) 89-98. (Pubitemid 46099074)
-
(2007)
International Journal of Pharmaceutics
, vol.330
, Issue.1-2
, pp. 89-98
-
-
Stigsnaes, P.1
Frokjaer, S.2
Bjerregaard, S.3
Van De Weert, M.4
Kingshott, P.5
Moeller, E.H.6
-
15
-
-
0036859983
-
High temperature biocatalysis by chemically modified cytochrome c
-
DOI 10.1021/bc025561p
-
H. Garcia-Arellano, B. Valderrama, G. Saab-Rincon, R. Vazquez-Duhalt, High temperature biocatalysis by chemically modified cytochrome c, Bioconjug. Chem. 13 (2002) 1336-1344. (Pubitemid 35420028)
-
(2002)
Bioconjugate Chemistry
, vol.13
, Issue.6
, pp. 1336-1344
-
-
Garcia-Arellano, H.1
Valderrama, B.2
Saab-Rincon, G.3
Vazquez-Duhalt, R.4
-
16
-
-
0026536995
-
Detection and molecular-weight determination of polyethylene glycol-modified hirudin by staining after sodium dodecyl-sulfate polyacrylamide-gel electrophoresis
-
M.M. Kurfurst, Detection and molecular-weight determination of polyethylene glycol-modified hirudin by staining after sodium dodecyl-sulfate polyacrylamide-gel electrophoresis, Anal. Biochem. 200 (1992) 2244-2248.
-
(1992)
Anal. Biochem.
, vol.200
, pp. 2244-2248
-
-
Kurfurst, M.M.1
-
17
-
-
0034659669
-
Thermochemistry of the specific binding of C12 surfactants to bovine serum albumin
-
DOI 10.1016/S0167-4838(00)00012-1, PII S0167483800000121
-
A.D. Nielsen, K. Borch, P. Westh, Thermochemistry of the specific binding of C12 surfactants to bovine serum albumin, BBA - Protein Struct. 1479 (2000) 321-331. (Pubitemid 30345650)
-
(2000)
Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology
, vol.1479
, Issue.1-2
, pp. 321-331
-
-
Nielsen, A.D.1
Borch, K.2
Westh, P.3
-
18
-
-
0026352256
-
Online characterization of polyethylene glycol-modified proteins
-
M. Kuntani, G. Dollinger, D. Johnson, L. Kresin, Online characterization of polyethylene glycol-modified proteins, J. Chromatogr. 588 (1991) 125-137.
-
(1991)
J. Chromatogr.
, vol.588
, pp. 125-137
-
-
Kuntani, M.1
Dollinger, G.2
Johnson, D.3
Kresin, L.4
-
19
-
-
33746254121
-
Proton exchange coupled to the specific binding of alkylsulfonates to serum albumins
-
DOI 10.1016/j.bbapap.2006.05.005, PII S1570963906002007
-
H. Lund, B.P. Christensen, A.D. Nielsen, P. Westh, Proton exchange coupled to the specific binding of alkylsulfonates to serum albumins, BBA - Proteins Proteom. 1764 (2006) 1243-1251. (Pubitemid 44088690)
-
(2006)
Biochimica et Biophysica Acta - Proteins and Proteomics
, vol.1764
, Issue.7
, pp. 1243-1251
-
-
Lund, H.1
Christensen, B.P.2
Nielsen, A.D.3
Westh, P.4
-
20
-
-
2542575542
-
Irreversible formation of intermediate BSA oligomers requires and induces conformational changes
-
DOI 10.1002/prot.20074
-
S.M. Vaiana, A. Emanuele, M.B. Palma-Vittorelli, M.U. Palma, Irreversible formation of intermediate BSA oligomers requires and induces conformational changes, Protein Struct. 55 (2004) 1053-1062. (Pubitemid 38702962)
-
(2004)
Proteins: Structure, Function and Genetics
, vol.55
, Issue.4
, pp. 1053-1062
-
-
Vaiana, S.M.1
Emanuele, A.2
Palma-Vittorelli, M.B.3
Palma, M.U.4
-
21
-
-
0025046965
-
Differential scanning calorimetric studies on bovine serum albumin: 1. Effects of pH and ionic strength
-
DOI 10.1016/0141-8130(90)90007-W
-
M. Yamasaki, H. Yano, K. Aoki, Differential scanning calorimetric studies on bovine serum-albumin. 1. Effects of pH and ionic-strength, Int. J. Biol. Macromol. 12 (1990) 263-268. (Pubitemid 20269615)
-
(1990)
International Journal of Biological Macromolecules
, vol.12
, Issue.4
, pp. 263-268
-
-
Yamasaki, M.1
Yano, H.2
Aoki, K.3
-
22
-
-
0027097992
-
Differential scanning calorimetric studies on bovine serum albumin: III. Effect of sodium dodecyl sulphate
-
DOI 10.1016/S0141-8130(05)80070-4
-
M. Yamasaki, H. Yano, K. Aoki, Differential scanning calorimetric studies on bovine serum-albumin. 3. Effect of sodium dodecyl-sulfate, Int. J. Biol. Macromol. 14 (1992) 305-312. (Pubitemid 23026015)
-
(1992)
International Journal of Biological Macromolecules
, vol.14
, Issue.6
, pp. 305-312
-
-
Yamasaki, M.1
Yano, H.2
Aoki, K.3
-
23
-
-
0030465765
-
Differential scanning calorimetric studies on bovine serum albumin IV. Effect of anionic surfactants with various lengths of hydrocarbon chain
-
DOI 10.1016/S0141-8130(96)01133-6, PII S0141813096011336
-
M. Yamasaki, T.Y. Isoda, H. Yano, K. Tatsumi, K. Aoki, Differential scanning calorimetric studies on bovine serum albumin. 4. Effect of anionic surfactants with various lengths of hydrocarbon chain, Int. J. Biol. Macromol. 19 (1996) 241-246. (Pubitemid 27053026)
-
(1996)
International Journal of Biological Macromolecules
, vol.19
, Issue.4
, pp. 241-246
-
-
Yamasaki, M.1
Yamashita, T.2
Yano, H.3
Tatsumi, K.4
Aoki, K.5
-
24
-
-
0030979596
-
DSC studies on bovine serum albumin denaturation effects of ionic strength and SDS concentration
-
DOI 10.1016/S0141-8130(97)01159-8, PII S0141813097011598
-
C. Giancola, C. DeSena, D. Fessas, G. Graziano, G. Barone, DSC studies on bovine serum albumin denaturation - effects of ionic strength and SDS concentration, Int. J. Biol. Macromol. 20 (1997) 193-204. (Pubitemid 27281595)
-
(1997)
International Journal of Biological Macromolecules
, vol.20
, Issue.3
, pp. 193-204
-
-
Giancola, C.1
De Sena, C.2
Fessas, D.3
Graziano, G.4
Barone, G.5
-
25
-
-
0026409134
-
Differential scanning calorimetric studies on bovine serum-albumin. 2. Effects of neutral salts and urea
-
M. Yamasaki, H. Yano, K. Aoki, Differential scanning calorimetric studies on bovine serum-albumin. 2. Effects of neutral salts and urea, Int. J. Biol. Macromol. 13 (1991) 322-328.
-
(1991)
Int. J. Biol. Macromol.
, vol.13
, pp. 322-328
-
-
Yamasaki, M.1
Yano, H.2
Aoki, K.3
-
26
-
-
0037289151
-
Thermal stability of bovine serum albumin DSC study
-
A. Michnik, Thermal stability of bovine serum albumin DSC study, J. Therm. Anal. Calorim. 71 (2003) 509-519.
-
(2003)
J. Therm. Anal. Calorim.
, vol.71
, pp. 509-519
-
-
Michnik, A.1
-
27
-
-
23444456924
-
How to study proteins by circular dichroism
-
DOI 10.1016/j.bbapap.2005.06.005, PII S1570963905001792
-
S.M. Kelly, T.J. Jess, N.C. Price, How to study proteins by circular dichroism, BBA - Proteins Proteom. 1751 (2005) 119-139. (Pubitemid 41112231)
-
(2005)
Biochimica et Biophysica Acta - Proteins and Proteomics
, vol.1751
, Issue.2
, pp. 119-139
-
-
Kelly, S.M.1
Jess, T.J.2
Price, N.C.3
-
28
-
-
56749121968
-
Stabilization of alpha-chymotrypsin upon PEGylation correlates with reduced structural dynamics
-
J.A. Rodriguez-Martinez, R.J. Sola, B. Castillo, H.R. Cintron-Colon, I. Rivera-Rivera, G. Barletta, K. Griebenow, Stabilization of alpha-chymotrypsin upon PEGylation correlates with reduced structural dynamics, Biotechnol. Bioeng. 101 (2008) 1142-1149.
-
(2008)
Biotechnol. Bioeng.
, vol.101
, pp. 1142-1149
-
-
Rodriguez-Martinez, J.A.1
Sola, R.J.2
Castillo, B.3
Cintron-Colon, H.R.4
Rivera-Rivera, I.5
Barletta, G.6
Griebenow, K.7
-
29
-
-
0001002352
-
Conformation changes of proteins
-
R. Lumry, H. Eyring, Conformation changes of proteins, J. Phys. Chem. 58 (1954) 110-120.
-
(1954)
J. Phys. Chem.
, vol.58
, pp. 110-120
-
-
Lumry, R.1
Eyring, H.2
-
30
-
-
33646154457
-
Modulation of protein aggregation by polyethylene glycol conjugation: GCSF as a case study
-
R.S. Rajan, T.S. Li, M. Aras, C. Sloey, W. Sutherland, H. Arai, R. Briddell, O. Kinstler, A.M.K. Lueras, Y. Zhang, H. Yeghnazar, M. Treuheit, D.N. Brems, Modulation of protein aggregation by polyethylene glycol conjugation: GCSF as a case study, Protein Sci. 15 (2006) 1063-1075.
-
(2006)
Protein Sci.
, vol.15
, pp. 1063-1075
-
-
Rajan, R.S.1
Li, T.S.2
Aras, M.3
Sloey, C.4
Sutherland, W.5
Arai, H.6
Briddell, R.7
Kinstler, O.8
Lueras, A.M.K.9
Zhang, Y.10
Yeghnazar, H.11
Treuheit, M.12
Brems, D.N.13
-
31
-
-
0025700693
-
Thermodynamic parameters for binding of fatty-acids to human serum-albumin
-
A.O. Pedersen, B. Honore, R. Brodersen, Thermodynamic parameters for binding of fatty-acids to human serum-albumin, Eur. J. Biochem. 190 (1990) 497-502.
-
(1990)
Eur. J. Biochem.
, vol.190
, pp. 497-502
-
-
Pedersen, A.O.1
Honore, B.2
Brodersen, R.3
-
32
-
-
0027412944
-
Biothermodynamic characterization of monocarboxylic and dicarboxylic aliphatic acids binding to human serum albumin: A flow microcalorimetric study
-
DOI 10.1016/0301-4622(93)87010-T
-
H. Aki, M. Yamamoto, Biothermodynamic characterization of monocarboxylic and dicarboxylic aliphatic-acids binding to human serum-albumin - a flow microcalorimetric study, Biophys. Chem. 46 (1993) 91-99. (Pubitemid 23053148)
-
(1993)
Biophysical Chemistry
, vol.46
, Issue.1
, pp. 91-99
-
-
Aki, H.1
Yamamoto, M.2
-
33
-
-
0032720125
-
Fatty acid binding to human serum albumin: New insights from crystallographic studies
-
DOI 10.1016/S1388-1981(99)00148-1, PII S1388198199001481
-
S. Curry, P. Brick, N.P. Franks, Fatty acid binding to human serum albumin: new insights from crystallographic studies, BBA - Mol. Cell. Biol. L. 1441 (1999) 131-140. (Pubitemid 29537733)
-
(1999)
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, vol.1441
, Issue.2-3
, pp. 131-140
-
-
Curry, S.1
Brick, P.2
Franks, N.P.3
-
34
-
-
0015528761
-
Method for measuring binding of small molecules to proteins from binding-induced alterations of physical-chemical properties
-
C.J. Halfman, T. Nishida, Method for measuring binding of small molecules to proteins from binding-induced alterations of physical-chemical properties, Biochemistry 11 (1972) 3493-3498.
-
(1972)
Biochemistry
, vol.11
, pp. 3493-3498
-
-
Halfman, C.J.1
Nishida, T.2
-
35
-
-
0034634370
-
Crystallographic analysis reveals common modes of binding of medium and long-chain fatty acids to human serum albumin
-
A.A. Bhattacharya, T. Grune, S. Curry, Crystallographic analysis reveals common modes of binding of medium and long-chain fatty acids to human serum albumin, J. Mol. Biol. 303 (2000) 721-732.
-
(2000)
J. Mol. Biol.
, vol.303
, pp. 721-732
-
-
Bhattacharya, A.A.1
Grune, T.2
Curry, S.3
|