Simultaneous quantification of three iridoids in rat plasma after oral administration of Zhi-zi-chi decoction using LC-MS

Journal of Separation Science

Volumn 34, Issue 20, 2011, Pages 2854-2860

  Long, Zhi Min ^a   Bi, Kai Shun ^a   Huo, Yan Shuang ^a   Yan, Xiao Yu ^a   Zhao, Xu ^a   Chen, Xiao Hui ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

6 Hydroxygeniposide; Genipin gentiobioside; Geniposide; Pharmacokinetics study; Zhi zi chi decoction

Indexed keywords

ANALYTES; GENIPIN; GENIPOSIDE; INTERNAL STANDARDS; IRIDOIDS; LINEAR RANGE; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; LOWER LIMIT OF QUANTIFICATIONS; ORAL ADMINISTRATION; PLASMA SAMPLES; PROTEIN PRECIPITATION; RAT PLASMA; RUNTIMES; SALIDROSIDE; SIMULTANEOUS DETERMINATIONS; VALIDATED METHODS; ZHI-ZI-CHI DECOCTION;

ACETONITRILE; BODY FLUIDS; FORMIC ACID; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS;

RATS;

6 ALPHA HYDROXYGENIPOSIDE; GENIPIN GENTIOBIOSIDE; GENIPOSIDE; IRIDOID; SALIDROSIDE; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; DRUG STRUCTURE; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; GARDENIA; IRIDOIDS; MALE; MASS SPECTROMETRY; RATS; RATS, WISTAR; SOYBEANS;

RATTUS;

EID: 80054980200     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201100387     Document Type: Article

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