Antidepressant-like effect of genipin in mice

Neuroscience Letters

Volumn 479, Issue 3, 2010, Pages 236-239

  Tian, Jun Sheng ^a   Cui, Yuan Lu ^a   Hu, Li Min ^a   Gao, Shan ^a   Chi, Wei ^a   Dong, Tian Jiao ^a   Liu, Lu Ping ^a  

^a TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Antidepressant; Genipin; Neurotransmitter; Reserpine; Traditional Chinese Medicine

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; FLUOXETINE; GENIPIN; MONOAMINE; NEUROTRANSMITTER; NORADRENALIN; RESERPINE; SEROTONIN; ANTIDEPRESSANT AGENT; BIOGENIC AMINE; IRIDOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEPRESSION; FORCED SWIMMING TEST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; HYPOTHERMIA; IMMOBILIZATION; LOCOMOTION; MOUSE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PTOSIS; SINGLE DRUG DOSE; ANIMAL; ANIMAL BEHAVIOR; BLEPHAROPTOSIS; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; MALE; METABOLISM; MOTOR ACTIVITY; PSYCHOLOGY;

ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; BIOGENIC MONOAMINES; BLEPHAROPTOSIS; DEPRESSION; DISEASE MODELS, ANIMAL; FLUOXETINE; HINDLIMB SUSPENSION; HIPPOCAMPUS; HYPOTHERMIA; IRIDOIDS; MALE; MICE; MICE, INBRED ICR; MOTOR ACTIVITY; RESERPINE; IRIDOID GLYCOSIDES;

EID: 77954141711     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.05.069     Document Type: Article

References (20)

1. Akao T., Kobayashi K., Aburada M. Enzymic studies on the animal and intestinal bacterial metabolism of geniposide. Biol. Phar. Bull. 1994, 17:1573-1576.
2. Yamamoto M., Miura N., Ohtake N., Amagya S. Genipin, a metabolite derived from the herbal inchin-ko-to, and suppression of fas-induced lethal liver apoptosis in mice. Gastroenterology 2000, 118:380-389.
3. Bourin M, Poncelet M., Chermat R., Simon P. The value of the reserpine test in psychopharmacology. Arzneimittel-Forschung 1983, 33:1173-1176.
4. Cryan J.F., Holmes A. The ascent of mouse: advances in modeling human depression and anxiety. Nutr. Rev. 2005, 4:775-790.
5. Herrera M.R., Mora S., Viana G.S. Antidepressant and anxiolytic effects of hydroalcoholic extract from Salvia elegans. J. Ethnopharmacol. 2006, 107:53-58.
6. Kleber E.T., Obry S., Hippeli W., Elstner E.F. Biochemical activities of extracts from Hypericum perforatum L. Arzneimittel-Forschung 1999, 49:106-109.
7. Koo H.J., Song Y.S., Kim H.J., Park E.H. Antiinflammatory effects of genipin, an active principle of gardenia. Eur. J. Pharmacol. 2004, 495:201-208.
8. Mao Q.Q., Huang Z. Antidepressant drugs and animal models of depression, Foreign Medical Sciences. Sec. Psychiatry 2005, 32:216-220.
9. Mario W., Manfred S.Z. Hypericum perforatum: a modern herbal antidepressant. Clin. Pharmacokinet. 2006, 45:449-468.
10. Millan M.J. The role of monamines in the actions of established and novel antidepressant agents: a critical review. Eur. J. Pharmacol. 2004, 500:371-384.
11. Parton L.E., Ye C.P., Coppari R. Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity. Nature 2007, 449:228-233.
12. Porsolt R.D., Jalfre M., Bertin A. Behavioral despair in mice: a primary screening test for antidepressants. Arch. Int. Pharmacodyn. Ther. 1977, 229:326-327.
13. Renard C.E., Dailly E., David D.J. Monoamine metabolism changes following the mouse forced swimming test but not the tail suspension test. Fundam. Clin. Pharmacol. 2003, 17:449-455.
14. Sánchez-Mateo C.C., Bonkanka C.X., Prado B., Rabanal R.M. Antidepressant activity of some Hypericum reflexum L. Fil. extracts in the forced swimming test in mice. J. Ethnopharmacol. 2007, 112:115-121.
15. Steru L., Chermat R., Thierry B. The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology (Berl.) 1985, 85:367-370.
16. Wang Y.T., Tan Q.R., Sun L.L., Cao J., Dou K.F., Xia B., Wang W. Possible therapeutic effect of a Traditional Chinese Medicine, si-ni-san, on chronic restraint stress related disorders. Neurosci. Lett. 2009, 449:215-219.
17. Yamazaki M, Chiba K. Genipin exhibits neurotrophic effects through a common signaling pathway in nitric oxide synthase-expressing cell. Eur. J. Pharmacol. 2008, 581:255-261.
18. Yamazaki M., Chiba K., Mohri T. Neuritogenic effect of natural irioid compounds on PC12h cells and its possible relation to signaling protein kinases. Biol. Phar. Bull. 1996, 19:791-795.
19. Yi L.T., Li Y.C., Pan Y., Li J.M., Kung H.F. Antidepressant-like effects of psoralidin isolated from the seeds of Psoralea corylifolia in the forced swimming test in mice. Prog. Neuropsychopharmacol. Biol. Psychiatry 2008, 32:510-519.
20. Zheng H.Z., Dong Z.H., Yu J. Modern Research and Application of Chinese Traditional Medicine 2000, vol.4. Academy Press, Beijing, China, 3166 pp.