Development of 2,3,5-triaryl-1H-pyrroles as estrogen receptorα selective ligands

ChemMedChem

Volumn 6, Issue 11, 2011, Pages 2055-2062

  Schäfer, Anja ^b   Wellner, Anja ^b   Strauss, Martin ^b   Wolber, Gerhard ^b   Gust, Ronald ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Autoxidation; Cytotoxicity; Drug design; Hormones; Nitrogen heterocycles

Indexed keywords

1 (2 METHYLPROPYL) 2,3,5 TRIS(4 HYDROXYPHENYL) 1H PYRROLE; 1,3,5 TRIS(4 HYDROXYPHENYL) 4 PROPYLPYRAZOLE; ESTROGEN RECEPTOR ALPHA; PARTIAL AGONIST; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STABILITY; HORMONE INHIBITION; PRIORITY JOURNAL;

BREAST NEOPLASMS; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG EVALUATION, PRECLINICAL; DRUG STABILITY; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTROGEN RECEPTOR MODULATORS; FEMALE; HUMANS; MODELS, MOLECULAR; PHENOLS; PYRAZOLES; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80054966981     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100283     Document Type: Article

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