Synthesis and investigations on the oxidative degradation of C3/C5-Alkyl-1,2,4-triarylpyrroles as ligands for the estrogen receptor

ChemMedChem

Volumn 6, Issue 5, 2011, Pages 794-803

  Schäfer, Anja ^b   Wellner, Anja ^b   Gust, Ronald ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Autoxidation; Cytotoxicity; Drug design; Hormones; Nitrogen heterocycles

Indexed keywords

1,2,4 TRIS(4 HYDROXY PHENYL) 3 PROPYL 1H PYRROLE; ALKYL GROUP; ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; LIGAND; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL ACTIVITY; CELL STRAIN MCF 7; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR STABILITY; OXIDATION; PRIORITY JOURNAL; RECEPTOR BINDING; SYNTHESIS;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG DESIGN; ESTROGEN RECEPTOR ALPHA; HUMANS; LIGANDS; OXIDATION-REDUCTION; PROTEIN BINDING; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79955036033     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201000537     Document Type: Article

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