메뉴 건너뛰기




Volumn 29, Issue 11, 2011, Pages 1738-1751

Systemic delivery of bone marrow-derived mesenchymal stromal cells diminishes neuropathology in a mouse model of Krabbe's disease

Author keywords

Axonal regeneration; Krabbe's disease; Leukodystrophy; Mesenchymal stromal cell; Twitcher mice

Indexed keywords

ANTIBODY; BRAIN DERIVED NEUROTROPHIC FACTOR; K 252A; PSYCHOSINE;

EID: 80054957115     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.724     Document Type: Article
Times cited : (24)

References (60)
  • 1
    • 0023684504 scopus 로고
    • Infantile and fetal globoid cell leukodystrophy: Analysis of galactosylceramide and galactosylsphingosine
    • Kobayashi T, Goto I, Yamanaka T et al. Infantile and fetal globoid cell leukodystrophy: Analysis of galactosylceramide and galactosylsphingosine. Ann Neurol 1988;24:517-522.
    • (1988) Ann Neurol , vol.24 , pp. 517-522
    • Kobayashi, T.1    Goto, I.2    Yamanaka, T.3
  • 2
    • 77950551326 scopus 로고    scopus 로고
    • Mesenchymal stromal cells: Current understanding and clinical status
    • Salem HK, Thiemermann C. Mesenchymal stromal cells: Current understanding and clinical status. Stem Cells 2010;28:585-596.
    • (2010) Stem Cells , vol.28 , pp. 585-596
    • Salem, H.K.1    Thiemermann, C.2
  • 4
    • 36248932643 scopus 로고    scopus 로고
    • Concise review: Mesenchymal stem cells: Their phenotype, differentiation capacity, immunological features, and potential for homing
    • DOI 10.1634/stemcells.2007-0197
    • Chamberlain G, Fox J, Ashton B et al. Concise review: Mesenchymal stem cells: Their phenotype, differentiation capacity, immunological features, and potential for homing. Stem Cells 2007;25:2739-2749. (Pubitemid 350127858)
    • (2007) Stem Cells , vol.25 , Issue.11 , pp. 2739-2749
    • Chamberlain, G.1    Fox, J.2    Ashton, B.3    Middleton, J.4
  • 5
    • 56549111768 scopus 로고    scopus 로고
    • Study of oncogenic transformation in ex vivo expanded mesenchymal cells, from paediatric bone marrow
    • Choumerianou DM, Dimitriou H, Perdikogianni C et al. Study of oncogenic transformation in ex vivo expanded mesenchymal cells, from paediatric bone marrow. Cell Prolif 2008;41:909-922.
    • (2008) Cell Prolif , vol.41 , pp. 909-922
    • Choumerianou, D.M.1    Dimitriou, H.2    Perdikogianni, C.3
  • 6
    • 60849136593 scopus 로고    scopus 로고
    • Mesenchymal stem cell homing: The devil is in the details
    • Karp JM, Leng Teo GS. Mesenchymal stem cell homing: The devil is in the details. Cell Stem Cell 2009;4:206-216.
    • (2009) Cell Stem Cell , vol.4 , pp. 206-216
    • Karp, J.M.1    Leng Teo, G.S.2
  • 7
    • 33746424373 scopus 로고    scopus 로고
    • Mesenchymal stem cells as trophic mediators
    • DOI 10.1002/jcb.20886
    • Caplan AI, Dennis JE. Mesenchymal stem cells as trophic mediators. J Cell Biochem 2006;98:1076-1084. (Pubitemid 44128350)
    • (2006) Journal of Cellular Biochemistry , vol.98 , Issue.5 , pp. 1076-1084
    • Caplan, A.I.1    Dennis, J.E.2
  • 9
    • 15544376664 scopus 로고    scopus 로고
    • Plasticity of cultured mesenchymal stem cells: Switch from nestin-positive to excitable neuron-like phenotype
    • DOI 10.1634/stemcells.2004-0149
    • Wislet-Gendebien S, Hans G, Leprince P et al. Plasticity of cultured mesenchymal stem cells: switch from nestin-positive to excitable neuron- like phenotype. Stem Cells 2005;23:392-402. (Pubitemid 40404458)
    • (2005) Stem Cells , vol.23 , Issue.3 , pp. 392-402
    • Wislet-Gendebien, S.1    Hans, G.2    Leprince, P.3    Rigo, J.-M.4    Moonen, G.5    Rogister, B.6
  • 10
    • 33845547990 scopus 로고    scopus 로고
    • Transdifferentiated mesenchymal stem cells as alternative therapy in supporting nerve regeneration and myelination
    • DOI 10.1007/s10571-006-9029-9, Proceedings of the 5th International Symposium on Experimental and Clinical Neurobiology, High Tatras, Slovakia, September 2005
    • Keilhoff G, Stang F, Goihl A et al. Transdifferentiated mesenchymal stem cells as alternative therapy in supporting nerve regeneration and myelination. Cell Mol Neurobiol 2006;26:1235-1252. (Pubitemid 44924044)
    • (2006) Cellular and Molecular Neurobiology , vol.26 , Issue.7-8 , pp. 1235-1252
    • Keilhoff, G.1    Stang, F.2    Goihl, A.3    Wolf, G.4    Fansa, H.5
  • 11
    • 57949102222 scopus 로고    scopus 로고
    • How do mesenchymal stromal cells exert their therapeutic benefit?
    • Horwitz EM, Dominici M. How do mesenchymal stromal cells exert their therapeutic benefit? Cytotherapy 2008;10:771-774.
    • (2008) Cytotherapy , vol.10 , pp. 771-774
    • Horwitz, E.M.1    Dominici, M.2
  • 12
    • 0030964590 scopus 로고    scopus 로고
    • Molecular genetics of krabbe disease (Globoid cell Leukodystrophy): Diagnostic and clinical implications
    • DOI 10.1002/(SICI)1098-1004(1997)10:4<268::AID-HUMU2>3.0.CO;2-D
    • Wenger DA, Rafi MA, Luzi P. Molecular genetics of Krabbe disease (globoid cell leukodystrophy): Diagnostic and clinical implications. Hum Mutat 1997;10:268-279. (Pubitemid 27430501)
    • (1997) Human Mutation , vol.10 , Issue.4 , pp. 268-279
    • Wenger, D.A.1    Rafi, M.A.2    Luzi, P.3
  • 13
    • 0021339782 scopus 로고
    • Progressive accumulation of toxic metabolite in a genetic leukodystrophy
    • Igisu H, Suzuki K. Progressive accumulation of toxic metabolite in a genetic leukodystrophy. Science 1984;224:753-755. (Pubitemid 14140043)
    • (1984) Science , vol.224 , Issue.4650 , pp. 753-755
    • Igisu, H.1    Suzuki, K.2
  • 14
    • 1642404670 scopus 로고    scopus 로고
    • Psychosine-induced apoptosis in a mouse oligodendrocyte progenitor cell line is mediated by caspase activation
    • DOI 10.1016/j.neulet.2003.12.126, PII S0304394004000515
    • Zaka M, Wenger DA. Psychosine-induced apoptosis in a mouse oligodendrocyte progenitor cell line is mediated by caspase activation. Neurosci Lett 2004;358:205-209. (Pubitemid 38368205)
    • (2004) Neuroscience Letters , vol.358 , Issue.3 , pp. 205-209
    • Zaka, M.1    Wenger, D.A.2
  • 17
    • 33747059890 scopus 로고    scopus 로고
    • Peripheral neuropathy in Krabbe disease: Effect of hematopoietic stem cell transplantation
    • DOI 10.1212/01.wnl.0000230156.01228.33, PII 0000611420060725000020
    • Siddiqi ZA, Sanders DB, Massey JM. Peripheral neuropathy in Krabbe disease: Effect of hematopoietic stem cell transplantation. Neurology 2006;67:268-272. (Pubitemid 44305411)
    • (2006) Neurology , vol.67 , Issue.2 , pp. 268-272
    • Siddiqi, Z.A.1    Sanders, D.B.2    Massey, J.M.3
  • 18
    • 0028785109 scopus 로고
    • Murine model of genetic demyelinating disease: The twitcher mouse
    • Suzuki K, Taniike M. Murine model of genetic demyelinating disease: The twitcher mouse. Microsc Res Technol 1995;32:204-214.
    • (1995) Microsc Res Technol , vol.32 , pp. 204-214
    • Suzuki, K.1    Taniike, M.2
  • 19
    • 0023735493 scopus 로고
    • Pathology of the peripheral nerve in the twitcher mouse following bone marrow transplantation
    • Kondo A, Hoogerbrugge PM, Suzuki K et al. Pathology of the peripheral nerve in the twitcher mouse following bone marrow transplantation. Brain Res 1988;460:178-183.
    • (1988) Brain Res , vol.460 , pp. 178-183
    • Kondo, A.1    Hoogerbrugge, P.M.2    Suzuki, K.3
  • 20
    • 34250680959 scopus 로고    scopus 로고
    • Peripheral nerve regeneration by the in vitro differentiated-human bone marrow stromal cells with Schwann cell property
    • DOI 10.1016/j.bbrc.2007.05.212, PII S0006291X07011813
    • Shimizu S, Kitada M, Ishikawa H et al. Peripheral nerve regeneration by the in vitro differentiated-human bone marrow stromal cells with Schwann cell property. Biochem Biophys Res Commun 2007;359:915-920. (Pubitemid 46946904)
    • (2007) Biochemical and Biophysical Research Communications , vol.359 , Issue.4 , pp. 915-920
    • Shimizu, S.1    Kitada, M.2    Ishikawa, H.3    Itokazu, Y.4    Wakao, S.5    Dezawa, M.6
  • 21
    • 0036676009 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell infusion for treatment of metachromatic leukodystrophy (MLD) and Hurler syndrome (MPS-IH)
    • DOI 10.1038/sj.bmt.1703650
    • Koc ON, Day J, Nieder M et al. Allogeneic mesenchymal stem cell infusion for treatment of metachromatic leukodystrophy (MLD) and Hurler syndrome (MPS-IH). Bone Marrow Transplant 2002;30:215-222. (Pubitemid 35023593)
    • (2002) Bone Marrow Transplantation , vol.30 , Issue.4 , pp. 215-222
    • Koc, O.N.1    Day, J.2    Nieder, M.3    Gerson, S.L.4    Lazarus, H.M.5    Krivit, W.6
  • 22
    • 68949135345 scopus 로고    scopus 로고
    • Interfacing Sca-1(pos) mesenchymal stem cells with biocompatible scaffolds with different chemical composition and geometry
    • Forte G, Franzese O, Pagliari S et al. Interfacing Sca-1(pos) mesenchymal stem cells with biocompatible scaffolds with different chemical composition and geometry. J Biomed Biotechnol 2009;2009:910610.
    • (2009) J Biomed Biotechnol , vol.2009 , pp. 910610
    • Forte, G.1    Franzese, O.2    Pagliari, S.3
  • 23
    • 0034040751 scopus 로고    scopus 로고
    • Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
    • DOI 10.1038/76095
    • Follenzi A, Ailles LE, Bakovic S et al. Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences. Nat Genet 2000;25:217-222. (Pubitemid 30394997)
    • (2000) Nature Genetics , vol.25 , Issue.2 , pp. 217-222
    • Follenzi, A.1    Ailles, L.E.2    Bakovic, S.3    Geuna, M.4    Naldini, L.5
  • 24
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for general users and for biologist programmers
    • Rozen S, Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 2000;132:365-386.
    • (2000) Methods Mol Biol , vol.132 , pp. 365-386
    • Rozen, S.1    Skaletsky, H.2
  • 25
    • 0035710746 scopus 로고    scopus 로고
    • -DeltaDeltaCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25:402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 26
    • 0036605564 scopus 로고    scopus 로고
    • Establishment and characterization of spontaneously immortalized Schwann cells from murine model of globoid cell leukodystrophy (twitcher)
    • DOI 10.1002/jnr.10247
    • Shen JS, Watabe K, Meng XL et al. Establishment and characterization of spontaneously immortalized Schwann cells from murine model of globoid cell leukodystrophy (twitcher). J Neurosci Res 2002;68:588-594. (Pubitemid 34575624)
    • (2002) Journal of Neuroscience Research , vol.68 , Issue.5 , pp. 588-594
    • Shen, J.-S.1    Watabe, K.2    Meng, X.-L.3    Ida, H.4    Ohashi, T.5    Eto, Y.6
  • 27
    • 39649122103 scopus 로고    scopus 로고
    • Myelination in mouse dorsal root ganglion/Schwann cell cocultures
    • Paivalainen S, Nissinen M, Honkanen H et al. Myelination in mouse dorsal root ganglion/Schwann cell cocultures. Mol Cell Neurosci 2008;37:568-578.
    • (2008) Mol Cell Neurosci , vol.37 , pp. 568-578
    • Paivalainen, S.1    Nissinen, M.2    Honkanen, H.3
  • 30
    • 63849199799 scopus 로고    scopus 로고
    • Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity
    • Fleming CE, Mar FM, Franquinho F et al. Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity. J Neurosci 2009;29:3220-3232.
    • (2009) J Neurosci , vol.29 , pp. 3220-3232
    • Fleming, C.E.1    Mar, F.M.2    Franquinho, F.3
  • 31
    • 0014431112 scopus 로고
    • A reliable staining method for semi-thin sections in experimental neurfanatomy
    • Hollander H, Vaaland JL. A reliable staining method for semi-thin sections in experimental neurfanatomy. Brain Res 1968;10:120-126.
    • (1968) Brain Res , vol.10 , pp. 120-126
    • Hollander, H.1    Vaaland, J.L.2
  • 32
    • 10444270290 scopus 로고    scopus 로고
    • Expression of telomerase extends the lifespan and enhances osteogenic differentiation of adipose tissue-derived stromal cells
    • DOI 10.1634/stemcells.2004-0023
    • Kang SK, Putnam L, Dufour J et al. Expression of telomerase extends the lifespan and enhances osteogenic differentiation of adipose tissuederived stromal cells. Stem Cells 2004;22:1356-1372. (Pubitemid 39636411)
    • (2004) Stem Cells , vol.22 , Issue.7 , pp. 1356-1372
    • Soo, K.K.1    Putnam, L.2    Dufour, J.3    Ylostalo, J.4    Jin, S.J.5    Bunnell, B.A.6
  • 33
    • 0035022053 scopus 로고    scopus 로고
    • Impairment of the blood-nerve and blood-brain barriers in apolipoprotein E knockout mice
    • DOI 10.1006/exnr.2001.7631
    • Fullerton SM, Shirman GA, Strittmatter WJ et al. Impairment of the blood-nerve and blood-brain barriers in apolipoprotein e knockout mice. Exp Neurol 2001;169:13-22. (Pubitemid 32427699)
    • (2001) Experimental Neurology , vol.169 , Issue.1 , pp. 13-22
    • Fullerton, S.M.1    Shirman, G.A.2    Strittmatter, W.J.3    Matthew, W.D.4
  • 34
    • 0026605762 scopus 로고
    • Characterization of 6-hexadecanoylamino- 4-methylumbelliferyl-beta-D- galactopyranoside as fluorogenic substrate of galactocerebrosidase for the diagnosis of Krabbe disease
    • Wiederschain G, Raghavan S, Kolodny E. Characterization of 6-hexadecanoylamino- 4-methylumbelliferyl-beta-D-galactopyranoside as fluorogenic substrate of galactocerebrosidase for the diagnosis of Krabbe disease. Clin Chim Acta 1992;205:87-96.
    • (1992) Clin Chim Acta , vol.205 , pp. 87-96
    • Wiederschain, G.1    Raghavan, S.2    Kolodny, E.3
  • 35
    • 33644796337 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Isolation, in vitro expansion and characterization
    • Beyer Nardi N, da Silva Meirelles L. Mesenchymal stem cells: Isolation, in vitro expansion and characterization. Handb Exp Pharmacol 2006;249-282.
    • (2006) Handb Exp Pharmacol , pp. 249-282
    • Beyer Nardi, N.1    Da Silva Meirelles, L.2
  • 37
    • 32644434557 scopus 로고    scopus 로고
    • Human mesenchymal stem cell subpopulations express a variety of neuro-regulatory molecules and promote neuronal cell survival and neuritogenesis
    • DOI 10.1016/j.expneurol.2005.10.029, PII S0014488605004048
    • Crigler L, Robey RC, Asawachaicharn A et al. Human mesenchymal stem cell subpopulations express a variety of neuro-regulatory molecules and promote neuronal cell survival and neuritogenesis. Exp Neurol 2006;198:54-64. (Pubitemid 43243744)
    • (2006) Experimental Neurology , vol.198 , Issue.1 , pp. 54-64
    • Crigler, L.1    Robey, R.C.2    Asawachaicharn, A.3    Gaupp, D.4    Phinney, D.G.5
  • 40
    • 4143122292 scopus 로고    scopus 로고
    • Dynamic of distribution of human bone marrow-derived mesenchymal stem cells after transplantation into adult unconditioned mice
    • DOI 10.1097/01.TP.0000128334.93343.B3
    • Allers C, Sierralta WD, Neubauer S et al. Dynamic of distribution of human bone marrow-derived mesenchymal stem cells after transplantation into adult unconditioned mice. Transplantation 2004;78:503-508. (Pubitemid 39097094)
    • (2004) Transplantation , vol.78 , Issue.4 , pp. 503-508
    • Allers, C.1    Sierralta, W.D.2    Neubauer, S.3    Rivera, F.4    Minguell, J.J.5    Conget, P.A.6
  • 42
    • 0029084244 scopus 로고
    • The twitcher mouse: A model for Krabbe disease and for experimental therapies
    • Suzuki K. The twitcher mouse: A model for Krabbe disease and for experimental therapies. Brain Pathol 1995;5:249-258.
    • (1995) Brain Pathol , vol.5 , pp. 249-258
    • Suzuki, K.1
  • 43
    • 0026595294 scopus 로고
    • K-252 compounds: Modulators of neurotrophin signal transduction
    • Knusel B, Hefti F. K-252 compounds: Modulators of neurotrophin signal transduction. J Neurochem 1992;59:1987-1996.
    • (1992) J Neurochem , vol.59 , pp. 1987-1996
    • Knusel, B.1    Hefti, F.2
  • 44
    • 0041488911 scopus 로고    scopus 로고
    • Trk receptors: Roles in neuronal signal transduction
    • DOI 10.1146/annurev.biochem.72.121801.161629
    • Huang EJ, Reichardt LF. Trk receptors: Roles in neuronal signal transduction. Annu Rev Biochem 2003;72:609-642. (Pubitemid 36930455)
    • (2003) Annual Review of Biochemistry , vol.72 , pp. 609-642
    • Huang, E.J.1    Reichardt, L.F.2
  • 45
    • 84863012475 scopus 로고    scopus 로고
    • Neural differentiation of brainderived neurotrophic factor-expressing human umbilical cord bloodderived mesenchymal stem cells in culture via TrkB-mediated ERK and beta-catenin phosphorylation and following transplantation into the developing brain
    • Epub ahead of print
    • Lim JY, Park SI, Kim SM et al. Neural differentiation of brainderived neurotrophic factor-expressing human umbilical cord bloodderived mesenchymal stem cells in culture via TrkB-mediated ERK and beta-catenin phosphorylation and following transplantation into the developing brain. Cell Transplant 2011 [Epub ahead of print].
    • (2011) Cell Transplant
    • Lim, J.Y.1    Park, S.I.2    Kim, S.M.3
  • 47
    • 80054123098 scopus 로고    scopus 로고
    • Effects of combining electrical stimulation with BDNF gene transfer on the regeneration of crushed rat sciatic nerve
    • Alrashdan MS, Sung MA, Kim Kwon Y et al. Effects of combining electrical stimulation with BDNF gene transfer on the regeneration of crushed rat sciatic nerve. Acta Neurochir (Wien) 2011;153:2021-2029.
    • (2011) Acta Neurochir (Wien) , vol.153 , pp. 2021-2029
    • Alrashdan, M.S.1    Sung, M.A.2    Kim Kwon, Y.3
  • 48
    • 43049161115 scopus 로고    scopus 로고
    • Self-renewal and differentiation capacity of young and aged stem cells
    • Roobrouck VD, Ulloa-Montoya F, Verfaillie CM. Self-renewal and differentiation capacity of young and aged stem cells. Exp Cell Res 2008;314:1937-1944.
    • (2008) Exp Cell Res , vol.314 , pp. 1937-1944
    • Roobrouck, V.D.1    Ulloa-Montoya, F.2    Verfaillie, C.M.3
  • 49
    • 0032923742 scopus 로고    scopus 로고
    • Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype
    • Jiang XR, Jimenez G, Chang E et al. Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nat Genet 1999;21:111-114.
    • (1999) Nat Genet , vol.21 , pp. 111-114
    • Jiang, X.R.1    Jimenez, G.2    Chang, E.3
  • 50
    • 0942301277 scopus 로고    scopus 로고
    • Intravenous Administration of Marrow Stromal Cells (MSCs) Increases the Expression of Growth Factors in Rat Brain after Traumatic Brain Injury
    • Mahmood A, Lu D, Chopp M. Intravenous administration of marrow stromal cells (MSCs) increases the expression of growth factors in rat brain after traumatic brain injury. J Neurotrauma 2004;21:33-39. (Pubitemid 38141800)
    • (2004) Journal of Neurotrauma , vol.21 , Issue.1 , pp. 33-39
    • Mahmood, A.1    Lu, D.2    Chopp, M.3
  • 51
    • 77953618096 scopus 로고    scopus 로고
    • Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome
    • Osaka M, Honmou O, Murakami T et al. Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome. Brain Res 2010;1343:226-235.
    • (2010) Brain Res , vol.1343 , pp. 226-235
    • Osaka, M.1    Honmou, O.2    Murakami, T.3
  • 52
    • 73149097202 scopus 로고    scopus 로고
    • Therapeutic benefits of human mesenchymal stem cells derived from bone marrow after global cerebral ischemia
    • Zheng W, Honmou O, Miyata K et al. Therapeutic benefits of human mesenchymal stem cells derived from bone marrow after global cerebral ischemia. Brain Res 2010;1310:8-16.
    • (2010) Brain Res , vol.1310 , pp. 8-16
    • Zheng, W.1    Honmou, O.2    Miyata, K.3
  • 53
    • 66249096305 scopus 로고    scopus 로고
    • Pulmonary passage is a major obstacle for intravenous stem cell delivery: The pulmonary first-pass effect
    • Fischer UM, Harting MT, Jimenez F et al. Pulmonary passage is a major obstacle for intravenous stem cell delivery: The pulmonary first-pass effect. Stem Cells Dev 2009;18:683-692.
    • (2009) Stem Cells Dev , vol.18 , pp. 683-692
    • Fischer, U.M.1    Harting, M.T.2    Jimenez, F.3
  • 54
    • 0023944811 scopus 로고
    • The twitcher mouse: Accumulation of galactosylsphingosine and pathology of the sciatic nerve
    • Tanaka K, Nagara H, Kobayashi T et al. The twitcher mouse: Accumulation of galactosylsphingosine and pathology of the sciatic nerve. Brain Res 1988;454:340-346.
    • (1988) Brain Res , vol.454 , pp. 340-346
    • Tanaka, K.1    Nagara, H.2    Kobayashi, T.3
  • 55
    • 33745030802 scopus 로고    scopus 로고
    • Intrinsic resistance of neural stem cells to toxic metabolites may make them well suited for cell non-autonomous disorders: Evidence from a mouse model of Krabbe leukodystrophy
    • Taylor RM, Lee JP, Palacino JJ et al. Intrinsic resistance of neural stem cells to toxic metabolites may make them well suited for cell non-autonomous disorders: Evidence from a mouse model of Krabbe leukodystrophy. J Neurochem 2006;97:1585-1599.
    • (2006) J Neurochem , vol.97 , pp. 1585-1599
    • Taylor, R.M.1    Lee, J.P.2    Palacino, J.J.3
  • 56
    • 0034601444 scopus 로고    scopus 로고
    • Collateral sprouting from sensory and motor axons into an end to side attached nerve segment
    • Kanje M, Arai T, Lundborg G. Collateral sprouting from sensory and motor axons into an end to side attached nerve segment. Neuroreport 2000;11:2455-2459. (Pubitemid 30622289)
    • (2000) NeuroReport , vol.11 , Issue.11 , pp. 2455-2459
    • Kanje, M.1    Arai, T.2    Lundborg, G.3
  • 57
    • 66049162131 scopus 로고    scopus 로고
    • Combined hematopoietic and lentiviral gene-transfer therapies in newborn Twitcher mice reveal contemporaneous neurodegeneration and demyelination in Krabbe disease
    • Galbiati F, Givogri MI, Cantuti L et al. Combined hematopoietic and lentiviral gene-transfer therapies in newborn Twitcher mice reveal contemporaneous neurodegeneration and demyelination in Krabbe disease. J Neurosci Res 2009;87:1748-1759.
    • (2009) J Neurosci Res , vol.87 , pp. 1748-1759
    • Galbiati, F.1    Givogri, M.I.2    Cantuti, L.3
  • 58
    • 79951849190 scopus 로고    scopus 로고
    • Mesenchymal-lineage stem cells have pronounced anti-inflammatory effects in the twitcher mouse model of Krabbe's disease
    • Ripoll CB, Flaat M, Klopf-Eiermann J et al. Mesenchymal-lineage stem cells have pronounced anti-inflammatory effects in the twitcher mouse model of Krabbe's disease. Stem Cells 2011;29:67-77.
    • (2011) Stem Cells , vol.29 , pp. 67-77
    • Ripoll, C.B.1    Flaat, M.2    Klopf-Eiermann, J.3
  • 59
    • 33847309067 scopus 로고    scopus 로고
    • Transplantation of bone marrow stromal cells for peripheral nerve repair
    • Chen CJ, Ou YC, Liao SL et al. Transplantation of bone marrow stromal cells for peripheral nerve repair. Exp Neurol 2007;204:443-453.
    • (2007) Exp Neurol , vol.204 , pp. 443-453
    • Chen, C.J.1    Ou, Y.C.2    Liao, S.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.