Evaluation of deleted in malignant brain tumors 1 (DMBT1) gene expression in bladder carcinoma cases: Preliminary study

Biomarkers

Volumn 16, Issue 7, 2011, Pages 610-615

  Dodurga, Yavuz ^a   Avci, Cigir Biray ^b   Yilmaz, Sunde ^b   Dogan, Z Ozlem ^b   Kesen, Zehra ^c   Tataroglu, Canten ^d   Satiroglu Tufan, N Lale ^a   Bushra, Tahmina ^a   Gunduz, Cumhur ^b  

^a PAMUKKALE UNIVERSITY   (Turkey)

^b EGE UNIVERSITY   (Turkey)

^c DENIZLI STATE HOSPITAL   (Turkey)

^d ADNAN MENDERES UNIVERSITY   (Turkey)

Author keywords

Bladder cancer; DMBT1 gene; gene expression; real time online RT PCR

Indexed keywords

MESSENGER RNA;

ADULT; AGED; ARTICLE; BLADDER CARCINOMA; CANCER GRADING; CANCER PATIENT; DBMT1 GENE; DOWN REGULATION; EVALUATION; FEMALE; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; ONCOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSITIONAL CELL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, TRANSITIONAL CELL; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MIDDLE AGED; NEOPLASM GRADING; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; URINARY BLADDER NEOPLASMS;

EID: 80054954113     PISSN: 1354750X     EISSN: 13665804     Source Type: Journal    
DOI: 10.3109/1354750X.2011.620627     Document Type: Article

References (23)

1. Bikker FJ, van der Wal JE, Ligtenberg AJ, Mollenhauer J, de Blieck-Hogervorst JM, van der Waal I, Poustka A, Nieuw Amerongen AV. (2004). Salivary agglutinin/DMBT1SAG expression is up-regulated in the presence of salivary gland tumors. J Dent Res 83:567-571. (Pubitemid 41766086)
2. Braidotti P, Nuciforo PG, Mollenhauer J, Poustka A, Pellegrini C, Moro A, Bulfamante G, Coggi G, Bosari S, Pietra GG. (2004). DMBT1 expression is down-regulated in breast cancer. BMC Cancer 4:46.doi:10.1186/1471-2407-4-46
3. Conde AR, Martins AP, Brito M, Manuel A, Ramos S, Malta-Vacas J, Renner M, Poustka A, Mollenhauer J, Monteiro C. (2007). DMBT1 is frequently downregulated in well-differentiated gastric carcinoma but more frequently upregulated across various gastric cancer types. Int J Oncol 30:1441-1446.
4. Dinney CP, McConkey DJ, Millikan RE, Wu X, Bar-Eli M, Adam L, Kamat AM, Siefker-Radtke AO, Tuziak T, Sabichi AL, Grossman HB, Benedict WF, Czerniak B. (2004). Focus on bladder cancer. Cancer Cell 6:111-116. (Pubitemid 39485683)
5. Du J, Guan M, Fan J, Jiang H. (2011). Loss of DMBT1 expression in human prostate cancer and its correlation with clinical progressive features. Urology 77:509.e9-509.13.Epub 2010 Dec 16.
6. El-Sebaie M, Zaghloul MS, Howard G, Mokhtar A. (2005). Squamous cell carcinoma of the bilharzial and non-bilharzial urinary bladder: a review of etiological features, natural history, and management. Int J Clin Oncol 10:20-25. (Pubitemid 40379490)
7. Huang YT, Lai PC, Wu CC, Hsu SH, Cheng CC, Lan YF, Chiu TH. (2010). BDNF mediated TrkB activation is a survival signal for transitional cell carcinoma cells. Int J Oncol 36:1469-1476.
8. Hustinx SR, Cao D, Maitra A, Sato N, Martin ST, Sudhir D, Iacobuzio- Donahue C, Cameron JL, Yeo CJ, Kern SE, Goggins M, Mollenhauer J, Pandey A, Hruban RH. (2004). Differentially expressed genes in pancreatic ductal adenocarcinomas identified through serial analysis of gene expression. Cancer Biol Ther 3:1254-1261. (Pubitemid 41350962)
9. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. (2009). Cancer statistics, 2009. CA Cancer J Clin 59:225-249.
10. Ligtenberg AJ, Veerman EC, Nieuw Amerongen AV, Mollenhauer J. (2007). Salivary agglutinin/glycoprotein-340/DMBT1: a single molecule with variable composition and with different functions in infection, inflammation and cancer. Biol Chem 388:1275-1289. (Pubitemid 350135572)
11. Mitra AP, Bartsch CC, Cote RJ. (2009). Strategies for molecular expression profiling in bladder cancer. Cancer Metastasis Rev 28:317-326.
12. Mollenhauer J, Helmke B, Müller H, Kollender G, Lyer S, Diedrichs L, Holmskov U, Ligtenberg T, Herbertz S, Krebs I, Wiemann S, Madsen J, Bikker F, Schmitt L, Otto HF, Poustka A. (2002). Sequential changes of the DMBT1 expression and location in normal lung tissue and lung carcinomas. Genes Chromosomes Cancer 35:164-169. (Pubitemid 34919973)
13. Mollenhauer J, Holmskov U, Wiemann S, Krebs I, Herbertz S, Madsen J, Kioschis P, Coy JF, Poustka A. (1999). The genomic structure of the DMBT1 gene: evidence for a region with susceptibility to genomic instability. Oncogene 18:6233-6240.
14. Mollenhauer J, Wiemann S, Scheurlen W, Korn B, Hayashi Y, Wilgenbus KK, von Deimling A, Poustka A. (1997). DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours. Nat Genet 17:32-39. (Pubitemid 27377529)
15. Mori M, Shiraishi T, Tanaka S, Yamagata M, Mafune K, Tanaka Y, Ueo H, Barnard GF, Sugimachi K. (1999). Lack of DMBT1 expression in oesophageal, gastric and colon cancers. Br J Cancer 79:211-213. (Pubitemid 29002287)
16. Muñoz J, Lázcoz P, Inda MM, Nistal M, Pestaña A, Encío IJ, Castresana JS. (2004). Homozygous deletion and expression of PTEN and DMBT1 in human primary neuroblastoma and cell lines. Int J Cancer 109:673-679. (Pubitemid 38405613)
17. Rosenstiel P, Sina C, End C, Renner M, Lyer S, Till A, Hellmig S, Nikolaus S, Fölsch UR, Helmke B, Autschbach F, Schirmacher P, Kioschis P, Hafner M, Poustka A, Mollenhauer J, Schreiber S. (2007). Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion. J Immunol 178:8203-8211. (Pubitemid 46898093)
18. Somerville RP, Shoshan Y, Eng C, Barnett G, Miller D, Cowell JK. (1998). Molecular analysis of two putative tumour suppressor genes, PTEN and DMBT, which have been implicated in glioblastoma multiforme disease progression. Oncogene 17:1755-1757. (Pubitemid 28482654)
19. Takeshita H, Sato M, Shiwaku HO, Semba S, Sakurada A, Hoshi M, Hayashi Y, Tagawa Y, Ayabe H, Horii A. (1999). Expression of the DMBT1 gene is frequently suppressed in human lung cancer. Jpn J Cancer Res 90:903-908. (Pubitemid 29500426)
20. Tchatchou S, Riedel A, Lyer S, Schmutzhard J, Strobel-Freidekind O, Gronert-Sum S, Mietag C, D'Amato M, Schlehe B, Hemminki K, Sutter C, Ditsch N, Blackburn A, Hill LZ, Jerry DJ, Bugert P, Weber BH, Niederacher D, Arnold N, Varon-Mateeva R, Wappenschmidt B, Schmutzler RK, Engel C, Meindl A, Bartram CR, Mollenhauer J, Burwinkel B. (2010). Identification of a DMBT1 polymorphism associated with increased breast cancer risk and decreased promoter activity. Hum Mutat 31:60-66.
21. Terada K, Tamiya T, Daido S, Kambara H, Tanaka H, Ono Y, Matsumoto K, Ito S, Ouchida M, Ohmoto T, Shimizu K. (2002). Prognostic value of loss of heterozygosity around three candidate tumor suppressor genes on chromosome 10q in astrocytomas. J Neurooncol 58:107-114. (Pubitemid 34784840)
22. Theodorescu D. (2006) Molecular biology of invasive and metastatic urothelial cancer. Textbook of Bladder Cancer. pp. 147-156
23. Wu W, Kemp BL, Proctor ML, Gazdar AF, Minna JD, Hong WK, Mao L. (1999). Expression of DMBT1, a candidate tumor suppressor gene, is frequently lost in lung cancer. Cancer Res 59:1846-1851. (Pubitemid 29186155)