The loss of endoglin promotes the invasion of extravillous trophoblasts

Endocrinology

Volumn 152, Issue 11, 2011, Pages 4386-4394

  Mano, Yukio ^a   Kotani, Tomomi ^a   Shibata, Kiyozumi ^a   Matsumura, Hiroko ^a   Tsuda, Hiroyuki ^a   Sumigama, Seiji ^b   Yamamoto, Eiko ^a   Iwase, Akira ^b   Senga, Takeshi ^c   Kikkawa, Fumitaka ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY HOSPITAL   (Japan)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ENDOGLIN; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA3; UROKINASE; UROKINASE RECEPTOR;

ARTICLE; CELL INVASION; CELL MOTILITY; CELL PROLIFERATION; CYTOTROPHOBLAST; EXTRAVILLOUS TROPHOBLAST; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TROPHOBLAST;

ANTIGENS, CD; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; HUMANS; MATRIX METALLOPROTEINASES; PLACENTA; PREGNANCY; RECEPTORS, CELL SURFACE; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA3; TROPHOBLASTS; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 80054940727     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1088     Document Type: Article

References (29)

1. Wang A, Rana S, Karumanchi SA 2009 Preeclampsia: the role of angiogenic factors in its pathogenesis. Physiology (Bethesda) 24: 147-158
2. Pijnenborg R, Anthony J, Davey DA, Rees A, Tiltman A, Vercruysse L, van Assche A 1991 Placental bed spiral arteries in the hypertensive disorders of pregnancy. Br J Obstet Gynaecol 98:648-655
3. Jones RL, Stoikos C, Findlay JK, Salamonsen LA 2006 TGF-β superfamily expression and actions in the endometrium and placenta. Reproduction 132:217-232 (Pubitemid 44269704)
4. Laresgoiti-Servitje E, Gómez-López N, Olson DM 2010 An immunological insight into the origins of pre-eclampsia. Hum Reprod Update 16:510-524
5. Hawinkels LJ, Kuiper P, Wiercinska E, Verspaget HW, Liu Z, Pardali E, Sier CF, ten Dijke P 2010 Matrix metalloproteinase-14 (MT1-MMP)-mediated endoglin shedding inhibits tumor angiogenesis. Cancer Res 70:4141-4150
6. Jeyabalan A, McGonigal S, Gilmour C, Hubel CA, Rajakumar A 2008 Circulating and placental endoglin concentrations in pregnancies complicated by intrauterine growth restriction and preeclampsia. Placenta 29:555-563
7. Farina A, Sekizawa A, De Sanctis P, Purwosunu Y, Okai T, Cha DH, Kang JH, Vicenzi C, Tempesta A, Wibowo N, Valvassori L, Rizzo N 2008 Gene expression in chorionic villous samples at 11 weeks'gestation from women destined to develop preeclampsia. Prenat Diagn 28:956-961
8. Founds SA, Conley YP, Lyons-Weiler JF, Jeyabalan A, Hogge WA, Conrad KP 2009 Altered global gene expression in first trimester placentas of women destined to develop preeclampsia. Placenta 30: 15-24
9. Yinon Y, Nevo O, Xu J, Many A, Rolfo A, Todros T, Post M, Caniggia I 2008 Severe intrauterine growth restriction pregnancies have increased placental endoglin levels: hypoxic regulation via transforming growth factor-β3. Am J Pathol 172:77-85 (Pubitemid 351186370)
10. Henry LA, Johnson DA, Sarrió D, Lee S, Quinlan PR, Crook T, Thompson AM, Reis-Filho JS, Isacke CM 2011 Endoglin expression in breast tumor cells suppresses invasion and metastasis and correlates with improved clinical outcome. Oncogene 30:1046-1058
11. Lala PK, Chakraborty C 2003 Factors regulating trophoblast migration and invasiveness: possible derangements contributing to pre-eclampsia and fetal injury. Placenta 24:575-587 (Pubitemid 37203312)
12. Lash GE, Hornbuckle J, Brunt A, Kirkley M, Searle RF, Robson SC, Bulmer JN 2007 Effect of low oxygen concentrations on trophoblast- like cell line invasion. Placenta 28:390-398 (Pubitemid 46593763)
13. Graham CH, Hawley TS, Hawley RG, MacDougall JR, Kerbel RS, Khoo N, Lala PK 1993 Establishment and characterization of first trimester human trophoblast cells with extended lifespan. Exp Cell Res 206:204-211 (Pubitemid 23212937)
14. Graham CH 1997 Effect of transforming growth factor-β on the plasminogen activator system in cultured first trimester human cytotrophoblasts. Placenta 18:137-143 (Pubitemid 27122748)
15. Zhu M, Gokhale VM, Szabo L, Munoz RM, Baek H, Bashyam S, Hurley LH, Von Hoff DD, Han H 2007 Identification of a novel inhibitor of urokinase-type plasminogen activator. Mol Cancer Ther 6:1348-1356 (Pubitemid 46711998)
16. Kotani T, Iwase A, Ino K, Sumigama S, Yamamoto E, Hayakawa H, Nagasaka T, Itakura A, Nomura S, Kikkawa F 2009 Activator protein- 2 impairs the invasion of a human extravillous trophoblast cell line. Endocrinology 150:4376-4385
17. Sato Y, Higuchi T, Yoshioka S, Tatsumi K, Fujiwara H, Fujii S 2003 Trophoblasts acquire a chemokine receptor, CCR1, as they differentiate towards invasive phenotype. Development 130:5519-5532 (Pubitemid 37484018)
18. Shido F, Ito T, Nomura S, Yamamoto E, Sumigama S, Ino K, Itakura A, Hattori A, Tsujimoto M, Mizutani S, Kikkawa F 2006 Endoplasmic reticulum aminopeptidase-1 mediates leukemia inhibitory factor-induced cell surface human leukocyte antigen-G expression in JEG-3 choriocarcinoma cells. Endocrinology 147:1780-1788
19. Uehara C, Ino K, Suzuki T, Kajiyama H, Kikkawa F, Nagasaka T, Mizutani S 2001 Up-regulation of neutral endopeptidase expression and enzymatic activity during the differentiation of human chorio-carcinoma cells. Placenta 22:540-549 (Pubitemid 32700838)
20. Lim JH, Kim SY, Park SY, Yang JH, Kim MY, Ryu HM 2008 Effective prediction of preeclampsia by a combined ratio of angio-genesis-related factors. Obstet Gynecol 111:1403-1409
21. St-Jacques S, Forte M, Lye SJ, Letarte M 1994 Localization of endoglin, a transforming growth factor-β binding protein, and of CD44 and integrins in placenta during the first trimester of pregnancy. Biol Reprod 51:405-413 (Pubitemid 24297612)
22. Caniggia I, Grisaru-Gravnosky S, Kuliszewsky M, Post M, Lye SJ 1999 Inhibition of TGF-β(3) restores the invasive capability of extravillous trophoblasts in preeclamptic pregnancies. J Clin Invest 103:1641-1650 (Pubitemid 29534358)
23. Ando N, Hirahara F, Fukushima J, Kawamoto S, Okuda K, Funabashi T, Gorai I, Minaguchi H 1998 Differential gene expression of TGF-β isoforms and TGF-β receptors during the first trimester of pregnancy at the human maternal-fetal interface. Am J Reprod Immunol 40:48-56 (Pubitemid 28306866)
24. Lee SB, Wong AP, Kanasaki K, Xu Y, Shenoy VK, McElrath TF, Whitesides GM, Kalluri R 2010 Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions. Am J Pathol 176:710-720
25. Bilban M, Tauber S, Haslinger P, Pollheimer J, Saleh L, Pehamberger H, Wagner O, Knöfler M 2010 Trophoblast invasion: assessment of cellular models using gene expression signatures. Placenta 31:989-996
26. Caniggia I, Taylor CV, Ritchie JW, Lye SJ, Letarte M 1997 Endoglin regulates trophoblast differentiation along the invasive pathway in human placental villous explants. Endocrinology 138:4977-4988 (Pubitemid 27460938)
27. Pérez-Gómez E, Del Castillo G, Juan Francisco S, López-Novoa JM, Bernabéu C, Quintanilla M 2010 The role of the TGF-β coreceptor endoglin in cancer. Scientific World Journal 10:2367-2384
28. LaMarca HL, Ott CM, Höner Zu Bentrup K, Leblanc CL, Pierson DL, Nelson AB, Scandurro AB, Whitley GS, Nickerson CA, Morris CA 2005 Three-dimensional growth of extravillous cytotrophoblasts promotes differentiation and invasion. Placenta 26:709-720 (Pubitemid 41535476)
29. Foidart JM, Munaut C, Chantraine F, Akolekar R, Nicolaides KH 2010 Maternal plasma soluble endoglin at 11-13 weeks' gestation in pre-eclampsia. Ultrasound Obstet Gynecol 35:680-687