Antiplatelet activity of Phellinus baummii methanol extract is mediated by cyclic AMP elevation and inhibition of collagen-activated integrin- α iibβ 3 and MAP kinase

Phytotherapy Research

Volumn 25, Issue 11, 2011, Pages 1596-1603

  Kamruzzaman, S M ^a   Endale, Mehari ^a   Oh, Won Jun ^a   Park, Seung Chun ^a   Kim, Tae Hwan ^a   Lee, In Kyoung ^b   Cho, Jae Youl ^c   Park, Hwa Jin ^d   Kim, Sang Keun ^e   Yun, Bong Sik ^b   Rhee, Man Hee ^a  

^a Kyungpook National University   (South Korea)

^b Chonbuk National University   (South Korea)

^c Kangwon National University   (South Korea)

^d Inje University   (South Korea)

^e Chungnam National University   (South Korea)

Author keywords

Cyclic AMP; Integrin IIb 3; MAP kinase; P. baumii; Platelets

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ADENOSINE TRIPHOSPHATE; ALPHA2BBETA3 INTEGRIN; ANTITHROMBOCYTIC AGENT; CALCIUM ION; COLLAGEN; CYCLIC AMP; FIBRINOGEN; INTEGRIN; JANUS KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PHELLINUS BAUMMII EXTRACT; PLANT EXTRACT; SP 60025; STRESS ACTIVATED PROTEIN KINASE 1; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPLATELET ACTIVITY; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; ENZYME PHOSPHORYLATION; ENZYME RELEASE; IC 50; MALE; MUSHROOM; NONHUMAN; PHELLINUS BAUMMII; PROTEIN BINDING; RAT; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

AGARICALES; ANIMALS; BASIDIOMYCOTA; BIOLOGICAL AGENTS; BLOOD PLATELETS; COLLAGEN; CYCLIC AMP; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RATS; RATS, SPRAGUE-DAWLEY; THROMBIN;

BASIDIOMYCOTA; INONOTUS BAUMII; PHELLINUS; RATTUS;

EID: 80054934478     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3450     Document Type: Article

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