Evaluation of the lipophilicity and prediction of biological activity of some N-cyclohexyl-N-substituted-2-phenylacetamide derivatives using RP-TLC

Journal of Planar Chromatography - Modern TLC

Volumn 24, Issue 5, 2011, Pages 435-440

  Vaštag, Dendi ^a   Perišić Janjić, Nada ^a   Tomić, Jelena ^b   Petrović, Slobodan ^b,c  

^a UNIVERSITY OF NOVI SAD   (Serbia)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c Hemofarm Group   (Serbia)

Author keywords

Lipophilicity; N cyclohexyl N substituted 2 phenylacetamide; RP C18 TLC

Indexed keywords

BLOOD-BRAIN BARRIER; ELUENTS; EXTRAPOLATION PROCEDURE; HUMAN INTESTINAL ABSORPTIONS; LINEAR RELATIONSHIPS; LIPOPHILICITY; LOG P-VALUE; MOBILE PHASE; N-CYCLOHEXYL-N-SUBSTITUTED-2-PHENYLACETAMIDE; ORGANIC MODIFIER; PHARMACOKINETICS PARAMETERS; PLASMA PROTEIN BINDING; RETENTION BEHAVIOR; REVERSED PHASE; RP-C18 TLC;

ACETONE; ACETONITRILE; BIOACTIVITY; BRAIN; ETHERS; INVESTMENTS; SUBSTITUTION REACTIONS;

THIN LAYER CHROMATOGRAPHY;

ACETANILIDE DERIVATIVE; ACETONE; ACETONITRILE; DIOXANE; WATER;

ARTICLE; BLOOD BRAIN BARRIER; CHEMICAL BOND; DRUG ACTIVITY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; INTESTINE ABSORPTION; LIPOPHILICITY; PHYSICAL CHEMISTRY; PREDICTION; REVERSED PHASE LIQUID CHROMATOGRAPHY; REVERSED PHASE THIN LAYER LIQUID CHROMATOGRAPHY; THIN LAYER CHROMATOGRAPHY;

EID: 80054926399     PISSN: 09334173     EISSN: 17890993     Source Type: Journal    
DOI: 10.1556/JPC.24.2011.5.13     Document Type: Article

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