Phenylacetamides as selective α-1A adrenergic receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 15, 2000, Pages 1621-1624

  Patane, Michael A ^a   DiPardo, Robert M ^a   Newton, Randall C ^a   Price, RoseAnn P ^a   Broten, Theodore P ^a   Chang, Raymond S L ^a   Ransom, Richard W ^a   Di Salvo, Jerry ^a   Nagarathnam, Dhanapalan ^b   Forray, Carlos ^b   Gluchowski, Charles ^b   Bock, Mark G ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b H LUNDBECK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACETANILIDE; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; DIHYDROPYRIDINE;

ANIMAL EXPERIMENT; ARTICLE; DOG; DRUG BINDING; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DESIGN; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

ACETAMIDES; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; RECEPTORS, ADRENERGIC, ALPHA-1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034618232     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00307-3     Document Type: Article

References (13)

1. Alpha-1a Adrenergic Receptor Antagonists, US5661163, 26 Aug 97