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Volumn 440, Issue 1, 2011, Pages 63-71

Induction of an incomplete autophagic response by cancer-preventive geranylgeranoic acid (GGA) in a human hepatoma-derived cell line

Author keywords

Autophagy; Geranylgeranoic acid (GGA); Hepatoma; LC3 cell; p62 sequestosome 1 (SQSTM1); Programmed cell death (PSD)

Indexed keywords

GERANYLGERANOIC ACID; GLUCOSE; GREEN FLUORESCENT PROTEIN; MITOCHONDRIAL ENZYME; PERETINOIN; PROTEIN P62; RED FLUORESCENT PROTEIN; SUPEROXIDE; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN;

EID: 80054923029     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20110610     Document Type: Article
Times cited : (20)

References (46)
  • 1
    • 0019766940 scopus 로고
    • In vitro binding affinity of novel synthetic polyprenoids (polyprenoic acids) to cellular retinoid-binding proteins
    • Muto, Y., Moriwaki, H. and Omori, M. (1981) In vitro binding affinity of novel synthetic polyprenoids (polyprenoic acids) to cellular retinoid-binding proteins. Gann 72, 974-977 (Pubitemid 12172470)
    • (1981) Gann, The Japanese Journal of Cancer Research , vol.72 , Issue.6 , pp. 974-977
    • Muto, Y.1    Moriwaki, H.2    Omori, M.3
  • 4
    • 0025695872 scopus 로고
    • Inhibitory effects of acyclic retinoid (polyprenoic acid) and its hydroxy derivative on cell growth and on secretion of α-fetoprotein in human hepatoma-derived cell line (PLC/PRF/5)
    • Fukutomi, Y., Omori, M., Muto, Y., Ninomiya, M., Okuno, M. and Moriwaki, H. (1990) Inhibitory effects of acyclic retinoid (polyprenoic acid) and its hydroxy derivative on cell growth and on secretion of α-fetoprotein in human hepatoma-derived cell line (PLC/PRF/5). Jpn J. Cancer Res. 81, 1281-1285
    • (1990) Jpn J. Cancer Res. , vol.81 , pp. 1281-1285
    • Fukutomi, Y.1    Omori, M.2    Muto, Y.3    Ninomiya, M.4    Okuno, M.5    Moriwaki, H.6
  • 5
    • 0021680733 scopus 로고
    • Antitumor activity of vitamin A and its derivatives
    • Muto, Y. and Moriwaki, H. (1994) Antitumor activity of vitamin A and its derivatives. J. Natl. Cancer Inst. 73, 1389-1393
    • (1994) J. Natl. Cancer Inst. , vol.73 , pp. 1389-1393
    • Muto, Y.1    Moriwaki, H.2
  • 7
    • 0033118925 scopus 로고    scopus 로고
    • Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma [4]
    • DOI 10.1056/NEJM199904013401315
    • Muto, Y., Moriwaki, H. and Saito, A. (1999) Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma. N. Engl. J. Med. 340, 1046-1047 (Pubitemid 29157643)
    • (1999) New England Journal of Medicine , vol.340 , Issue.13 , pp. 1046-1047
    • Muto, Y.1    Moriwaki, H.2    Saito, A.3
  • 8
    • 0031550232 scopus 로고    scopus 로고
    • Rapid loss in the mitochondrial membrane potential during geranylgeranoic acid-induced apoptosis
    • DOI 10.1006/bbrc.1996.5883
    • Shidoji, Y., Nakamura, N., Moriwaki, H. and Muto, Y. (1997) Rapid loss in the mitochondrial membrane potential during geranylgeranoic acid-induced apoptosis. Biochem. Biophys. Res. Commun. 230, 58-63 (Pubitemid 27210242)
    • (1997) Biochemical and Biophysical Research Communications , vol.230 , Issue.1 , pp. 58-63
    • Shidoji, Y.1    Nakamura, N.2    Moriwaki, H.3    Muto, Y.4
  • 9
    • 0030069102 scopus 로고    scopus 로고
    • Apoptosis in human hepatoma cell line induced by 4,5-didehydro geranylgeranoic acid (acyclic retinoid) via down-regulation of transforming growth factor-α
    • DOI 10.1006/bbrc.1996.0188
    • Nakamura, N., Shidoji, Y., Moriwaki, H. and Muto, Y. (1996) Apoptosis in human hepatoma cell line induced by 4,5-didehydro geranylgeranoic acid (acyclic retinoid) via down-regulation of transforming growth factor-α. Biochem. Biophys. Res. Commun. 219, 100-104 (Pubitemid 26071610)
    • (1996) Biochemical and Biophysical Research Communications , vol.219 , Issue.1 , pp. 100-104
    • Nakamura, N.1    Shidoji, Y.2    Moriwaki, H.3    Muto, Y.4
  • 10
    • 2542428247 scopus 로고    scopus 로고
    • Natural occurrence of cancer-preventive geranylgeranoic acid in medicinal herbs
    • DOI 10.1194/jlr.M300502-JLR200
    • Shidoji, Y. and Ogawa, H. (2004) Natural occurrence of cancer-preventive geranylgeranoic acid in medicinal herbs. J. Lipid Res. 45, 1092-1103 (Pubitemid 38679505)
    • (2004) Journal of Lipid Research , vol.45 , Issue.6 , pp. 1092-1103
    • Shidoji, Y.1    Ogawa, H.2
  • 12
    • 66449114033 scopus 로고    scopus 로고
    • P62 at the crossroads of autophagy, apoptosis, and cancer
    • Moscat, J. and Diaz-Meco, M.T. (2009) p62 at the crossroads of autophagy, apoptosis, and cancer. Cell 137, 1001-1004
    • (2009) Cell , vol.137 , pp. 1001-1004
    • Moscat, J.1    Diaz-Meco, M.T.2
  • 13
    • 0037005262 scopus 로고    scopus 로고
    • Autophagosome formation in mammalian cells
    • DOI 10.1247/csf.27.421
    • Mizushima, N., Ohsumi, Y. and Yoshimori, T. (2002) Autophagosome formation in mammalian cells. Cell Struct. Funct. 27, 421-429 (Pubitemid 36267711)
    • (2002) Cell Structure and Function , vol.27 , Issue.6 , pp. 421-429
    • Mizushima, N.1    Ohsumi, Y.2    Yoshimori, T.3
  • 14
    • 35448981935 scopus 로고    scopus 로고
    • Autophagy: From phenomenology to molecular understanding in less than a decade
    • Klionsky, D. J. (2007) Autophagy: from phenomenology to molecular understanding in less than a decade. Nat. Rev. Mol. Cell Biol. 8, 931-937
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 931-937
    • Klionsky, D.J.1
  • 15
    • 0347986620 scopus 로고    scopus 로고
    • 12 myotubes
    • DOI 10.1042/BJ20030826
    • Tassa, A., Roux, M. P., Attaix, D. and Bechet, D. M. (2003) Class III phosphoinositide 3-kinase-Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes. Biochem. J. 376, 577-586 (Pubitemid 38058057)
    • (2003) Biochemical Journal , vol.376 , Issue.3 , pp. 577-586
    • Tassa, A.1    Roux, M.P.2    Attaix, D.3    Bechet, D.M.4
  • 16
    • 0037004931 scopus 로고    scopus 로고
    • Diversity of signaling controls of macroautophagy in mammalian cells
    • DOI 10.1247/csf.27.431
    • Petiot, A., Pattingre, S., Arico, S., Meley, D. and Codogno, P. (2002) Diversity of signaling controls of macroautophagy in mammalian cells. Cell Struct. Funct. 27, 431-441 (Pubitemid 36267712)
    • (2002) Cell Structure and Function , vol.27 , Issue.6 , pp. 431-441
    • Petiot, A.1    Pattingre, S.2    Arico, S.3    Meley, D.4    Codogno, P.5
  • 17
    • 28844502647 scopus 로고    scopus 로고
    • Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy
    • DOI 10.1074/jbc.M509158200
    • Sugawara, K., Suzuki, N., Fujioka, Y., Mizushima, N., Ohsumi, Y. and Inagaki, F. (2005) Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy. J. Biol. Chem. 280, 40058-40065 (Pubitemid 41779140)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.48 , pp. 40058-40065
    • Sugawara, K.1    Suzuki, N.N.2    Fujioka, Y.3    Mizushima, N.4    Ohsumi, Y.5    Inagaki, F.6
  • 20
    • 38349158077 scopus 로고    scopus 로고
    • Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy
    • DOI 10.1038/nprot.2007.327, PII NPROT.2007.327
    • Mukhopadhyay, P., Rajesh, M., Hasko, G., Hawkins, B. J., Madesh, M. and Pacher, P. (2007) Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy. Nat. Protoc. 2, 2295-2301 (Pubitemid 351565867)
    • (2007) Nature Protocols , vol.2 , Issue.9 , pp. 2295-2301
    • Mukhopadhyay, P.1    Rajesh, M.2    Hasko, G.3    Hawkins, B.J.4    Madesh, M.5    Pacher, P.6
  • 21
    • 26844531363 scopus 로고    scopus 로고
    • Maturation of autophagic vacuoles in mammalian cells
    • Eskelinen, E.-L. (2005) Maturation of autophagic vacuoles in mammalian cells. Autophagy 1, 1-10
    • (2005) Autophagy , vol.1 , pp. 1-10
    • Eskelinen, E.-L.1
  • 22
    • 30044443008 scopus 로고    scopus 로고
    • Prevention of geranylgeranoic acid-induced apoptosis by phospholipid hydroperoxide glutathione peroxidase gene
    • DOI 10.1002/jcb.20627
    • Shidoji, Y., Okamoto, K., Muto, Y., Komura, S., Ohishi, N. and Yagi, K. (2006) Prevention of geranylgeranoic acid-induced apoptosis by phospholipid hydroperoxide glutathione peroxidase gene. J. Cell. Biochem. 97, 178-187 (Pubitemid 43050189)
    • (2006) Journal of Cellular Biochemistry , vol.97 , Issue.1 , pp. 178-187
    • Shidoji, Y.1    Okamoto, K.2    Muto, Y.3    Komura, S.4    Ohishi, N.5    Yagi, K.6
  • 23
    • 34249798692 scopus 로고    scopus 로고
    • Autophagic and apoptotic response to stress signals in mammalian cells
    • DOI 10.1016/j.abb.2007.02.006, PII S0003986107000793, Highlight Issue: Pro- and antiapoptotic Signalling
    • Ferraro, E. and Cecconi, F. (2007) Autophagic and apoptotic response to stress signals in mammalian cells. Arch. Biochem. Biophys. 462, 210-219 (Pubitemid 46856320)
    • (2007) Archives of Biochemistry and Biophysics , vol.462 , Issue.2 , pp. 210-219
    • Ferraro, E.1    Cecconi, F.2
  • 24
    • 33746108329 scopus 로고    scopus 로고
    • Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy
    • Tanida, I., Minematsu-Ikeguchi, N., Ueno, T. and Kominami, E. (2005) Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Autophagy 1, 84-91
    • (2005) Autophagy , vol.1 , pp. 84-91
    • Tanida, I.1    Minematsu-Ikeguchi, N.2    Ueno, T.3    Kominami, E.4
  • 25
    • 34548077575 scopus 로고    scopus 로고
    • Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
    • Kimura, S., Noda, T. and Yoshimori, T. (2007) Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 3, 452-460 (Pubitemid 47293726)
    • (2007) Autophagy , vol.3 , Issue.5 , pp. 452-460
    • Kimura, S.1    Noda, T.2    Yoshimori, T.3
  • 26
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • Mizushima, N. (2007) Autophagy: process and function. Genes Dev. 21, 2861-2873
    • (2007) Genes Dev. , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 27
    • 0030031099 scopus 로고    scopus 로고
    • Nineteenth century research on naturally occurring cell death and related phenomena
    • Clarke, P. G. and Clarke, S. (1996) Nineteenth century research on naturally occurring cell death and related phenomena. Anat. Embryol. 193, 81-99
    • (1996) Anat. Embryol. , vol.193 , pp. 81-99
    • Clarke, P.G.1    Clarke, S.2
  • 30
    • 79959346132 scopus 로고    scopus 로고
    • Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest
    • Ganley, I. G., Wong, P.-M., Gammoh, N. and Jiang, X. (2011) Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest. Mol. Cell 42, 731-743
    • (2011) Mol. Cell , vol.42 , pp. 731-743
    • Ganley, I.G.1    Wong, P.-M.2    Gammoh, N.3    Jiang, X.4
  • 31
    • 37349067228 scopus 로고    scopus 로고
    • Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells
    • DOI 10.1038/sj.cdd.4402233, PII 4402233, Special issue on Tumor stress, cell death and the ensuing immune response
    • Chen, Y., McMillan-Ward, E., Kong, J., Israels, S. J. and Gibson, S. B. (2008) Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells. Cell Death Differ. 15, 171-182 (Pubitemid 350286185)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.1 , pp. 171-182
    • Chen, Y.1    McMillan-Ward, E.2    Kong, J.3    Israels, S.J.4    Gibson, S.B.5
  • 32
    • 79953647105 scopus 로고    scopus 로고
    • Rapamycin treatment augments motor neuron degeneration in SOD1 (G93A) mouse model of amyotrophic lateral sclerosis
    • Zhang, X., Li, L., Chen, S., Yang, D., Wang, Y., Zhang, X., Wang, Z. and Le, W. (2011) Rapamycin treatment augments motor neuron degeneration in SOD1 (G93A) mouse model of amyotrophic lateral sclerosis. Autophagy 7, 412-425
    • (2011) Autophagy , vol.7 , pp. 412-425
    • Zhang, X.1    Li, L.2    Chen, S.3    Yang, D.4    Wang, Y.5    Zhang, X.6    Wang, Z.7    Le, W.8
  • 33
    • 38949203787 scopus 로고    scopus 로고
    • Is mitochondrial generation of reactive oxygen species a trigger for autophagy?
    • Chen, Y. and Gibson, S. B. (2008) Is mitochondrial generation of reactive oxygen species a trigger for autophagy? Autophagy 4, 246-248 (Pubitemid 351231192)
    • (2008) Autophagy , vol.4 , Issue.2 , pp. 246-248
    • Chen, Y.1    Gibson, S.B.2
  • 35
    • 41449113885 scopus 로고    scopus 로고
    • Altered macroautophagy in the spinal cord of SOD1 mutant mice
    • Li, L., Zhang, X. and Le, W. (2008) Altered macrophagy in the spinal cord of SOD1 mutant mice. Autophagy 4, 290-293 (Pubitemid 351458089)
    • (2008) Autophagy , vol.4 , Issue.3 , pp. 290-293
    • Li, A.1    Zhang, X.2    Le, W.3
  • 36
    • 0345856413 scopus 로고    scopus 로고
    • Insulin-dependent signaling regulates azurophil granule-selective macroautophagy in human myeloblastic cells
    • DOI 10.1189/jlb.0503211
    • Saeki, K., Hong, Z., Nakatsu, M., Yoshimori, T., Kabeya, Y., Yamamoto, A., Kaburagi, Y. and You, A. (2003) Insulin-dependent signaling regulates azurophil granule-selective macroautophagy in human myeloblastic cells. J. Leukocyte Biol. 74, 1108-1116 (Pubitemid 38040333)
    • (2003) Journal of Leukocyte Biology , vol.74 , Issue.6 , pp. 1108-1116
    • Saeki, K.1    Hong, Z.2    Nakatsu, M.3    Yoshimori, T.4    Kabeya, Y.5    Yamamoto, A.6    Kaburagi, Y.7    Yuo, A.8
  • 39
    • 59349105233 scopus 로고    scopus 로고
    • Monitoring autophagy in mammalian cultured cells through the dynamics of LC3
    • Kimura, S., Fijita, N., Noda, T. and Yoshimori, T. (2009) Monitoring autophagy in mammalian cultured cells through the dynamics of LC3. Methods Enzymol. 452, 1-12
    • (2009) Methods Enzymol. , vol.452 , pp. 1-12
    • Kimura, S.1    Fijita, N.2    Noda, T.3    Yoshimori, T.4
  • 40
    • 34247186472 scopus 로고    scopus 로고
    • Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
    • DOI 10.1038/sj.emboj.7601623, PII 7601623
    • Scherz-Shouval, R., Shvets, E., Fass, E., Shorer, H., Gil, L. and Elazar, Z. (2007) Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J. 26, 1749-1760 (Pubitemid 46624042)
    • (2007) EMBO Journal , vol.26 , Issue.7 , pp. 1749-1760
    • Scherz-Shouval, R.1    Shvets, E.2    Fass, E.3    Shorer, H.4    Gil, L.5    Elazar, Z.6
  • 42
    • 0023162026 scopus 로고
    • Ascorbic acid inhibits lysosomal autophagy of ferritin
    • Bridges, K.R. (1987) Ascorbic acid inhibits lysosomal autophagy of ferritin. J. Biol. Chem. 262, 14773-14778
    • (1987) J. Biol. Chem. , vol.262 , pp. 14773-14778
    • Bridges, K.R.1
  • 45


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