Synthesis and anticandidal activity of new triazolothiadiazine derivatives

European Journal of Medicinal Chemistry

Volumn 46, Issue 11, 2011, Pages 5562-5566

  Altntop, Mehlika Dilek ^a   Kaplanckl, Zafer Asm ^a   Turan Zitouni, Gülhan ^a   Özdemir, Ahmet ^a   Işcan, Gökalp ^a   Akaln, Gülşen ^a   Yildirim, Şafak Ulusoylar ^a  

^a ANADOLU UNIVERSITY   (Turkey)

Author keywords

Anticandidal activity; Cytotoxicity; Triazole; Triazolothiadiazine

Indexed keywords

3 (2 CYCLOHEXYLETHYL) 6 (4 CHLOROPHENYL) 7H 1,2,4 TRIAZOLO[3,4-B] 1,3,4 THIADIAZINE; 3 (2 CYCLOHEXYLETHYL) 6 (4 FLUOROPHENYL) 7H 1,2,4 TRIAZOLO[3,4-B] 1,3,4 THIADIAZINE; 3 (2 CYCLOHEXYLETHYL) 6 (4 METHYLPHENYL) 7H 1,2,4 TRIAZOLO[3,4-B] 1,3,4 THIADIAZINE; 3 (2 CYCLOHEXYLETHYL) 6 (4 NITROPHENYL) 7H 1,2,4 TRIAZOLO[3,4-B] 1,3,4 THIADIAZINE; 3 (2 CYCLOHEXYLETHYL) 6 PHENYL 7H 1,2,4 TRIAZOLO[3,4-B] 1,3,4 THIADIAZINE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3 [2 (4 HYDROXYPHENYL)ETHYL] 6 (4 CHLOROPHENYL) 7H 1,2,4 TRIAZOLO[3,4-B] 1,3,4 THIADIAZINE; 3 [2 (4 HYDROXYPHENYL)ETHYL] 6 (4 METHYLPHENYL) 7H 1,2,4 TRIAZOLO[3,4-B] 1,3,4 THIADIAZINE; 3 [2 (4 HYDROXYPHENYL)ETHYL] 6 (4 NITROPHENYL) 7H 1,2,4 TRIAZOLO[3,4-B] 1,3,4 THIADIAZINE; 3 [2 (4 HYDROXYPHENYL)ETHYL] 6 (4-FLUOROPHENYL) 7H 1,2,4 TRIAZOLO[3,4-B] 1,3,4 THIADIAZINE; 3 [2 (4 HYDROXYPHENYL)ETHYL] 6 PHENYL 7H 1,2,4 TRIAZOLO [3,4-B] 1,3,4 THIADIAZINE; ANTIFUNGAL AGENT; KETOCONAZOLE; THIADIAZINE DERIVATIVE; TRIAZOLOTHIADIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIFUNGAL ACTIVITY; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA KRUSEI; CANDIDA PARAPSILOSIS; CANDIDA TROPICALIS; CELL STRAIN 3T3; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; MICROBIAL SENSITIVITY TEST; MOUSE; NONHUMAN; RING CLOSING METATHESIS;

ANIMALS; ANTIFUNGAL AGENTS; CANDIDA; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG DISCOVERY; MICE; MICROBIAL SENSITIVITY TESTS; NIH 3T3 CELLS; THIADIAZINES;

EID: 80054900161     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.09.020     Document Type: Article

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