Synthesis and the selective antifungal activity of 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine derivatives

European Journal of Medicinal Chemistry

Volumn 45, Issue 5, 2010, Pages 2080-2084

  Özdemir, Ahmet ^a   Turan Zitouni, Gülhan ^a   Asim Kaplancikli, Zafer ^a   Işcan, Gökalp ^a   Khan, Shabana ^b   Demirci, Fatih ^a  

^a ANADOLU UNIVERSITY   (Turkey)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Candida spp.; Cytotoxicity; In vitro antifungal activity; Tetrahydroimidazo 1,2 a pyridine

Indexed keywords

5,6,7,8 TETRAHYDROIMIDAZO[1,2 A]PYRIDINE 2 CARBOXYLIC ACID (4 CYANOBENZYLIDENE)HYDRAZIDE; 5,6,7,8 TETRAHYDROIMIDAZO[1,2 A]PYRIDINE 2 CARBOXYLIC ACID(4 BROMOBENZYLIDENE)HYDRAZIDE; 5,6,7,8 TETRAHYDROIMIDAZO[1,2 A]PYRIDINE 2 CARBOXYLIC ACID(4 CHLOROBENZYLIDENE)HYDRAZIDE; 5,6,7,8 TETRAHYDROIMIDAZO[1,2 A]PYRIDINE 2 CARBOXYLIC ACID(4 DIMETHYLAMINOBENZYLIDENE)HYDRAZIDE; 5,6,7,8 TETRAHYDROIMIDAZO[1,2 A]PYRIDINE 2 CARBOXYLIC ACID(4 ISOPROPILBENZYLIDENE)HYDRAZIDE; 5,6,7,8 TETRAHYDROIMIDAZO[1,2 A]PYRIDINE 2 CARBOXYLIC ACID(4 METHYLBENZYLIDENE)HYDRAZIDE; 5,6,7,8 TETRAHYDROIMIDAZO[1,2 A]PYRIDINE 2 CARBOXYLIC ACID(4 NITROBENZYLIDENE)HYDRAZIDE; 5,6,7,8 TETRAHYDROIMIDAZO[1,2 A]PYRIDINE 2 CARBOXYLIC ACID(BENZO[ 1,3]DIOXOL 5 YLMETHYLENE)HYDRAZIDE; ANTIFUNGAL AGENT; HYDRAZIDE DERIVATIVE; UNCLASSIFIED DRUG;

AGAR DIFFUSION; ANIMAL CELL; ANTIFUNGAL ACTIVITY; ARTICLE; BREAST CARCINOMA; BROTH DILUTION; CANCER CELL CULTURE; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA KRUSEI; CANDIDA PARAPSILOSIS; CANDIDA TROPICALIS; CANDIDA ZEYLANOIDES; CARCINOMA CELL; CHEMICAL REACTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; KIDNEY EPITHELIUM; MAMMAL CELL; MASS SPECTROMETRY; MELANOMA CELL; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OVARY CARCINOMA; PICHIA JADINII; PROTON NUCLEAR MAGNETIC RESONANCE; SKIN CARCINOMA; SOLID TUMOR; STRUCTURE ACTIVITY RELATION;

ANTIFUNGAL AGENTS; CANDIDA; DOSE-RESPONSE RELATIONSHIP, DRUG; IMIDAZOLES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PYRIDINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 77949488933     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.12.023     Document Type: Article

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