Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human Bcells: Differential effects of BMP-6 and BMP-7

European Journal of Immunology

Volumn 41, Issue 11, 2011, Pages 3135-3145

  Huse, Kanutte ^a,b   Bakkebø, Maren ^a,b   Oksvold, Morten P ^a,b   Forfang, Lise ^a,b   Hilden, Vera I ^a,b   Stokke, Trond ^a   Smeland, Erlend B ^a,b   Myklebust, June H ^a,b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

B cells; Bone morphogenetic proteins; Maturation; Plasmablasts

Indexed keywords

ACTIVIN RECEPTOR LIKE KINASE 2; ACTIVIN RECEPTOR TYPE 2B; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CD27 ANTIGEN; CD38 ANTIGEN; CD40 LIGAND; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 21; OSTEOGENIC PROTEIN 1; PROTEIN SERINE THREONINE KINASE; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

APOPTOSIS; ARTICLE; B LYMPHOCYTE; BLAST CELL; CELL CYCLE ARREST; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; MEMORY CELL; NORMAL HUMAN; PLASMABLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION;

ANTIBODY FORMATION; B-LYMPHOCYTES; BONE MORPHOGENETIC PROTEIN 6; BONE MORPHOGENETIC PROTEIN 7; CD40 LIGAND; CELL DIFFERENTIATION; CELL SEPARATION; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULINS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGIC MEMORY; INTERLEUKINS; LYMPHOCYTE ACTIVATION; PLASMA CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 80054889742     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201141558     Document Type: Article

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