Not enough evidence to include ESR1 amplification

Nature Reviews Cancer

Volumn 11, Issue 11, 2011, Pages 823-

  Thomas, Christoforos ^a   Gustafsson, Jan Åke ^a,b  

^a University of Houston   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR ALPHA; TAMOXIFEN;

BREAST CANCER; COMPARATIVE GENOMIC HYBRIDIZATION; ESR1 GENE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE AMPLIFICATION; GENE FREQUENCY; HUMAN; NOTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; UPREGULATION;

EID: 80054857841     PISSN: 1474175X     EISSN: 14741768     Source Type: Journal    
DOI: 10.1038/nrc3093-c2     Document Type: Note

References (14)

1. Thomas, C. & Gustafsson, J.-Å. The different roles of ER subtypes in cancer biology and therapy. Nature Rev. Cancer 11, 597-608 (2011).
2. Yu. et al. ESR1 gene amplification: another mechanism regulating the cellular levels of ERα. Nature Rev. Cancer (doi:10.1038/nrc3093-c1).
3. Pan, X. et al. Elevated expression of CUEDC2 protein confers endocrine resistance in breast cancer. Nature Med. 17, 708-714 (2011).
4. Giamas, G. et al. Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer. Nature Med. 17, 715-719 (2011).
5. Al-Nakhle, H. et al. Estrogen receptor β1 expression is regulated by miR-92 in breast cancer. Cancer Res. 70, 4778-4784 (2010).
6. Zhu, X. et al. Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis. Am. J. Pathol. 164, 2003-2012 (2004).
7. Holst, F. et al. Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Nature Genet. 39, 655-660 (2007).
8. Brown, L. A. et al. ESR1 gene amplification in breast cancer: a common phenomenon? Nature Genet. 40, 806-812 (2008).
9. Horlings, H. M. et al. ESR1 gene amplification in breast cancer: a common phenomenon? Nature Genet. 40, 807-812 (2008).
10. Reis-Filho, J. S. et al. ESR1 gene amplification in breast cancer: a common phenomenon? Nature Genet. 40, 809-812 (2008).
11. Vincent-Salomon, A., Raynal, V., Lucchesi, C., Gruel, N. & Delattre, O. ESR1 gene amplification in breast cancer: a common phenomenon? Nature Genet. 40, 809-812 (2008).
12. Tan, D. S., Lambros, M. B., Marchio, C. & Reis-Filho, J. S. ESR1 amplification in endometrial carcinomas: hope or hyperbole? J. Path. 216, 271-274 (2008).
13. Moelans, C. B. et al. ESR1 amplification is rare in breast cancer and is associated with high grade and high proliferation: a multiplex ligation-dependent probe amplification study. Cell Oncol. (Dordr) (doi:10.1007/s13402-011-0045-5).
14. Nielsen, K. V. et al. Amplification of ESR1 may predict resistance to adjuvant tamoxifen in postmenopausal patients with hormone receptor positive breast cancer. Breast Cancer Res.Treat 127, 345-355 (2011).