Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer

Nature Medicine

Volumn 17, Issue 6, 2011, Pages 715-719

  Giamas, Georgios ^a   Filipović, Aleksandra ^a   Jacob, Jimmy ^a   Messier, Walter ^b   Zhang, Hua ^a   Yang, Dongyun ^c   Zhang, Wu ^c   Shifa, Belul Assefa ^a   Photiou, Andrew ^a   Tralau Stewart, Cathy ^a   Castellano, Leandro ^a   Green, Andrew R ^d   Coombes, R Charles ^a   Ellis, Ian O ^d   Ali, Simak ^a   Lenz, Heinz Josef ^c   Stebbing, Justin ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b Evolutionary Genomics Inc   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR ALPHA; LEMUR TYROSINE KINASE 3; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE FER; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST CANCER; DISEASE FREE SURVIVAL; ENZYMATIC DEGRADATION; ENZYME ACTIVITY; ENZYME POLYMORPHISM; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION;

ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; BREAST NEOPLASMS; DRUG RESISTANCE, NEOPLASM; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOTYPE; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; POLYMORPHISM, GENETIC; RNA, SMALL INTERFERING; TAMOXIFEN;

LEMUR;

EID: 79958093406     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2351     Document Type: Article

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