Cathepsin S is activated during colitis and causes visceral hyperalgesia by a PAR2-dependent mechanism in mice

Gastroenterology

Volumn 141, Issue 5, 2011, Pages 1864-1874.e3

  Cattaruzza, Fiore ^a   Lyo, Victoria ^a   Jones, Ella ^a   Pham, David ^a   Hawkins, James ^a   Kirkwood, Kimberley ^a   Valdez Morales, Eduardo ^b   Ibeakanma, Charles ^b   Vanner, Stephen J ^b   Bogyo, Matthew ^c   Bunnett, Nigel W ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b QUEEN S UNIVERSITY   (Canada)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MONASH UNIVERSITY   (Australia)

Author keywords

Activity Based Probes; Inflammation; Pain; Protease Activated Receptors; Proteases

Indexed keywords

CATHEPSIN B; CATHEPSIN L; CATHEPSIN S; CATHEPSIN S INHIBITOR; MORPHOLINUREA LEUCINE HOMOPHENYLALANINE VINYLPHENYLSULFONE; PIROXICAM; PROTEINASE ACTIVATED RECEPTOR 2; TRINITROBENZENESULFONIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; CONTROLLED STUDY; ELECTROPHORESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; GASTROINTESTINAL PAIN; GEL ELECTROPHORESIS; GENE DELETION; HYPERALGESIA; MICROGLIA; MOUSE; NOCICEPTIVE RECEPTOR; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; RADIOIMMUNOPRECIPITATION; SPINAL CORD NERVE CELL;

EID: 80054846758     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.07.035     Document Type: Article

References (7)

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