Absence of phagocyte NADPH oxidase 2 leads to severe inflammatory response in lungs of mice infected with Coccidioides

Microbial Pathogenesis

Volumn 51, Issue 6, 2011, Pages 432-441

  Gonzalez, Angel ^a,b,c,d   Hung, Chiung Yu ^a   Cole, Garry T ^a  

^a UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

^b Unidad de Biología Celular y Molecular   (Colombia)

^c UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^d UNIVERSIDAD PONTIFICIA BOLIVARIANA   (Colombia)

Author keywords

Coccidioides; Coccidioidomycosis; NADPH oxidase 2; NOX2 knock out mice; ROS

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TRANSCRIPTION FACTOR FOXP3;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMOKINESIS; COCCIDIOIDES; COCCIDIOIDOMYCOSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENZYME ACTIVITY; ENZYME MECHANISM; FUNGUS SPORE; IN VITRO STUDY; INNATE IMMUNITY; KNOCKOUT MOUSE; LUNG HOMOGENATE; LUNG INFILTRATE; LYMPHOCYTIC INFILTRATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PATHOGEN LOAD; PHAGOCYTE; PHAGOCYTOSIS; PNEUMONIA; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SPLEEN; SURVIVAL RATE; T LYMPHOCYTE SUBPOPULATION; WILD TYPE;

ANIMALS; COCCIDIOIDES; COCCIDIOIDOMYCOSIS; COLONY COUNT, MICROBIAL; CYTOKINES; DISEASE MODELS, ANIMAL; FUNGAL VACCINES; INFLAMMATION; LUNG; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; NADPH OXIDASE; PHAGOCYTES; REACTIVE OXYGEN SPECIES; SPLEEN; SURVIVAL ANALYSIS; T-LYMPHOCYTES, REGULATORY; TIME FACTORS;

COCCIDIOIDES; MURINAE; MUS;

EID: 80054835271     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2011.08.003     Document Type: Article

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