Anti-FcεR1 antibody injections activate basophils and mast cells and delay Type 1 diabetes onset in NOD mice

Clinical Immunology

Volumn 141, Issue 2, 2011, Pages 205-217

  Hübner, Marc P ^a,b   Larson, David ^a   Torrero, Marina N ^a   Mueller, Ellen ^a   Shi, Yinghui ^a   Killoran, Kristin E ^a   Mitre, Edward ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Fc R1; ; Histamine; ; IgE; IL 4; ; Nonobese diabetic (NOD); ; Type 1 diabetes;

Indexed keywords

CIMETIDINE; FC EPSILON R1 ANTIBODY; FEXOFENADINE; HISTAMINE; INTERLEUKIN 4; RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASOPHIL; CELL ACTIVATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HISTAMINE RELEASE; IN VITRO STUDY; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE;

ANIMALS; ANTIBODIES; AUTOANTIBODIES; BASOPHILS; CELL DEGRANULATION; CRICETINAE; CRICETULUS; DIABETES MELLITUS, TYPE 1; HELMINTHIASIS; HISTAMINE ANTAGONISTS; HISTAMINE RELEASE; HUMANS; IMMUNOGLOBULIN E; INSULIN; INTERLEUKIN-4; MAST CELLS; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MODELS, IMMUNOLOGICAL; RECEPTORS, IGE; TH1 CELLS;

EID: 80054834739     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2011.08.004     Document Type: Article

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