Chronic morphine alters the presynaptic protein profile: Identification of novel molecular targets using proteomics and network analysis

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Abul Husn, Noura S ^a   Annangudi, Suresh P ^b,c   Ma'ayan, Avi ^a   Ramos Ortolaza, Dinah L ^a   Stockton, Steven D ^a   Gomes, Ivone ^a   Sweedler, Jonathan V ^b   Devi, Lakshmi A ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c DOW AGROSCIENCES LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA TUBULIN; CHAPERONE; CITRATE SYNTHASE; CONTACTIN 1; CYSTEINE STRING PROTEIN; DIHYDROLIPOAMIDE DEHYDROGENASE; G SEPTIN GAMMA; GELDANAMYCIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HEXOKINASE; HEXOKINASE 2; MORPHINE; N ETHYLMALEIMIDE SENSITIVE FACTOR; NALOXONE; NERVE CELL ADHESION MOLECULE; PROTEIN 14 3 3; PROTEIN 14 3 3 DELTA; PROTEIN 14 3 3 ZETA; SEPTIN; SEPTIN 7; SYNTAXIN; SYNTAXIN BINDING PROTEIN 1; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR AP 2 COMPLEX SUBUNIT ALPHA 2; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL 2; VOLTAGE DEPENDENT ANION CHANNEL 3; HEAT SHOCK PROTEIN 40; MEMBRANE PROTEIN; PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CLUSTER ANALYSIS; CONTROLLED STUDY; CORPUS STRIATUM; DOWN REGULATION; DRUG TARGETING; ISOTOPE LABELING; MALE; MORPHINE ADDICTION; NEUROTRANSMISSION; NONHUMAN; PRESYNAPTIC NERVE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PROTEOMICS; RAT; THEORETICAL STUDY; UPREGULATION; ANIMAL; CHEMISTRY; CHRONIC DISEASE; DRUG EFFECT; METABOLISM; METHODOLOGY; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; SYNAPTOSOME;

RATTUS;

ANIMALS; CHRONIC DISEASE; CLUSTER ANALYSIS; HSP40 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; MEMBRANE PROTEINS; MOLECULAR CHAPERONES; MORPHINE; MORPHINE DEPENDENCE; PRESYNAPTIC TERMINALS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEINS; PROTEOMICS; RATS; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

EID: 80054769817     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025535     Document Type: Article

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