Synthesis and evaluation of 7-substituted-3,4-dihydrobenzo[f][1,4]oxazepin- 5(2H)-ones as anticonvulsant and hypnotic agents

Medicinal Chemistry Research

Volumn 20, Issue 7, 2011, Pages 996-1004

  Deng, Xian Qing ^a   Song, Ming Xia ^a   Wei, Cheng Xi ^b   Sun, Zhi Gang ^b   Quan, Zhe Shan ^a  

^a YANBIAN UNIVERSITY   (China)

^b INNER MONGOLIA UNIVERSITY FOR NATIONALITIES   (China)

Author keywords

1,4 Benzoxazepin 5(2H) one; Anticonvulsant; Hypnosis; Maximal electroshock; Synthesis

Indexed keywords

6 METHOXY 2,3 DIHYDROCHROMEN 4 ONE OXIME DERIVATIVE; 7 (HEPTYLOXY) 3,4 DIHYDROBENZO[F][1,4]OXAZEPIN 5(2H) ONE DERIVATIVE; 7 (HEPTYLOXY)3,4 DIHYDROBENZO[F] [1,4]OXAZEPIN 5(2H) ONE DERIVATIVE; 7 (HEXYLOXY) 3,4 DIHYDROBENZO[F][1,4]OXAZEPIN 5(2H) ONE DERIVATIVE; 7 (PENTYLOXY) 3,4 DIHYDROBENZO[F][1,4]OXAZEPIN 5(2H) ONE DERIVATIVE; 7 3,4 DIHYDROBENZO[F] [1,4]OXAZEPIN 5(2H) ONE DERIVATIVE; 7 ALKYLOXYL 3,4 DIHYDROBENZO[F][1,4]OXAZEPIN 5(2H) ONE DERIVATIVE; 7 ETHOXY 3,4 DIHYDROBENZO[F][1,4]OXAZEPIN 5(2H) ONE DERIVATIVE; 7 HYDROXY 3,4 DIHYDROBENZO[F][1,4]OXAZEPIN5(2H) ONE DERIVATIVE; 7 METHOXY 3,4 DIHYDROBENZO[F][1,4]OXAZEPIN 5(2H) ONE DERIVATIVE; 7 PROPOXY 3,4 DIHYDROBENZO[F][1,4]OXAZEPIN 5(2H) ONE DERIVATIVE; ANTICONVULSIVE AGENT; HYPNOTIC AGENT; OXAZEPINE DERIVATIVE; PENTOBARBITAL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; DRUG EFFECT; DRUG POTENCY; DRUG SYNTHESIS; ELECTRIC SHOCK; FEMALE; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SLEEP;

EID: 80054766209     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-010-9434-y     Document Type: Article

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