Synthesis of novel 7-benzylamino-2H-1,4-benzoxazin-3(4H)-ones as anticonvulsant agents

European Journal of Medicinal Chemistry

Volumn 43, Issue 6, 2008, Pages 1216-1221

  Piao, Zhong Tai ^a   Guan, Li Ping ^a   Zhao, Li Ming ^a   Piao, Hu Ri ^a   Quan, Zhe Shan ^a  

^a YANBIAN UNIVERSITY   (China)

Author keywords

1,4 Benzoxazin 3(4H) one; Anticonvulsant; Isoniazid; MES; sc PTZ; Strychnine

Indexed keywords

7 (2 CHLOROBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (2 FLUOROBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (2,4 DICHLOROBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (3 CHLOROBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (3 FLUOROBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (3,4 METHYLENEDIOOXYBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (4 BROMOBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (4 CHLOROBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (4 ETHOXYBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (4 FLUOROBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (4 HYDROXYBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (4 METHOXYBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (4 METHYLBENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 (BENZYLAMINO) 2H 1,4 BENZOXAZIN 3 (4H)ONE; 7 BENZYLAMINO 2H 1,4 BENZOXAZIN 3 (4H)ONE; ANTICONVULSIVE AGENT; ISONIAZID;

ANTICONVULSANT ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; DRUG SCREENING; DRUG SYNTHESIS; NONHUMAN;

ANIMALS; ANTICONVULSANTS; BENZOXAZINES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; SPECTROPHOTOMETRY, INFRARED;

EID: 44349117304     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.08.006     Document Type: Article

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