Adjunctive tests for diagnosis of tuberculosis: Serology, ELISPOT for site-specific lymphocytes, urinary lipoarabinomannan, string test, and fine needle aspiration

Journal of Infectious Diseases

Volumn 204, Issue SUPPL. 4, 2011, Pages

  Achkar, Jacqueline M ^a   Lawn, Stephen D ^b,c   Moosa, Mahomed Yunus S ^d   Wright, Colleen A ^e   Kasprowicz, Victoria O ^d,f,g  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^d UNIVERSITY OF KWAZULU NATAL   (South Africa)

^e UNIVERSITY OF STELLENBOSCH   (South Africa)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^g UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; LIPOARABINOMANNAN; MYCOBACTERIUM ANTIGEN;

ANTIBODY DETECTION; ANTIGEN ANTIBODY REACTION; ARTICLE; ASPIRATION BIOPSY; CHILDHOOD DISEASE; DIAGNOSTIC TEST; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTERFERON GAMMA RELEASE ASSAY; LOWER RESPIRATORY TRACT; LUNG TUBERCULOSIS; LYMPH NODE BIOPSY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SEROLOGY; SPUTUM ANALYSIS; STRING SIGN; T LYMPHOCYTE; TUBERCULOSIS; TUBERCULOUS MENINGITIS; URINALYSIS; URINARY LIPOARABINOMANNAN;

BACTERIOLOGICAL TECHNIQUES; BIOPSY, FINE-NEEDLE; ENZYME-LINKED IMMUNOSPOT ASSAY; HIV INFECTIONS; HUMANS; INTERFERON-GAMMA RELEASE TESTS; LIPOPOLYSACCHARIDES; MYCOBACTERIUM TUBERCULOSIS; SEROLOGIC TESTS; SPECIMEN HANDLING; TUBERCULOSIS;

EID: 80054762488     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jir450     Document Type: Article

References (147)

1. World Health Organization. Global tuberculosis control: a short update to the 2009 report. Geneva, Switzerland:WHO, 2009. http://whqlibdoc. who.int/publications/2009/9789241598866-eng.pdf.
2. World Health Organization. TB/HIV facts 2009. Geneva, Switzerland: WHO, 2009.http://www.who.int/tb/challenges/hiv/factsheet-hivtb-2009update.pdf
3. World Health Organization. Improving the diagnosis and treatment of smear-negative pulmonary and tuberculosis among adults and adolescents: Recommendations for HIV-prevalent and resourceconstrained settings. Geneva, Switzerland: Stop TB Department of HIV/AIDS, 2007.
4. Perkins MD, Cunningham J. Facing the crisis: improving the diagnosis of tuberculosis in the HIV era. J Infect Dis 2007; 196(Suppl 1):S15-27. (Pubitemid 47206081)
5. Harries AD, Hargreaves NJ, Graham SM, et al. Childhood tuberculosis in Malawi: nationwide case-finding and treatment outcomes. Int J Tuberc Lung Dis 2002; 6:424-31. (Pubitemid 34492166)
6. Updated guidelines for the use of nucleic acid amplification tests in the diagnosis of tuberculosis. MMWR Morb Mortal Wkly Rep 2009; 58:7-10.
7. Diagnostic Standards and Classification of Tuberculosis in Adults and Children. This official statement of the American Thoracic Society and the Centers for Disease Control and Prevention was adopted by the ATS Board of Directors, July 1999. This statement was endorsed by the Council of the Infectious Disease Society of America, September 1999. Am J Respir Crit Care Med 2000; 161:1376-95.
8. Al Zahrani K, Al Jahdali H, Poirier L, Rene P, Gennaro ML, Menzies D. Accuracy and utility of commercially available amplification and serologic tests for the diagnosis of minimal pulmonary tuberculosis. Am J Respir Crit Care Med 2000; 162:1323-9.
9. Lim TK, Gough A, Chin NK, Kumarasinghe G. Relationship between estimated pretest probability and accuracy of automated Mycobacterium tuberculosis assay in smear-negative pulmonary tuberculosis. Chest 2000; 118:641-7.
10. Boehme CC, Nabeta P, Hillemann D, et al. Rapid molecular detection of tuberculosis and rifampin resistance. N Engl J Med 2010; 363:1005-15.
11. Centers for Disease Control and Prevention. Reported tuberculosis in the United States 2006. Atlanta, GA: U.S. Department of Health and Human Services, 2007.
12. Elliott AM, Namaambo K, Allen BW, et al. Negative sputum smear results in HIV-positive patients with pulmonary tuberculosis in Lusaka, Zambia. Tuber Lung Dis 1993; 74:191-4. (Pubitemid 23188682)
13. Lawson L, Yassin MA, Ramsay A, Emenyonu NE, Squire SB, Cuevas LE. Comparison of scanty AFB smears against culture in an area with high HIV prevalence. Int J Tuberc Lung Dis 2005; 9:933-5. (Pubitemid 41139655)
14. Colebunders RL, Ryder RW, Nzilambi N, et al. HIV infection in patients with tuberculosis in Kinshasa, Zaire. Am Rev Respir Dis 1989; 139:1082-5. (Pubitemid 19139824)
15. Karstaedt AS, Jones N, Khoosal M, Crewe-Brown HH. The bacteriology of pulmonary tuberculosis in a population with high human immunodeficiency virus seroprevalence. Int J Tuberc Lung Dis 1998; 2:312-6. (Pubitemid 28168308)
16. Nunn P, Mungai M, Nyamwaya J, et al. The effect of human immunodeficiency virus type-1 on the infectiousness of tuberculosis. Tuber Lung Dis 1994; 75:25-32. (Pubitemid 24128756)
17. Gold JA, Rom WN, Harkin TJ. Significance of abnormal chest radiograph findings in patients with HIV-1 infection without respiratory symptoms. Chest 2002; 121:1472-7. (Pubitemid 34499658)
18. Raviglione MC, Narain JP, Kochi A. HIV-associated tuberculosis in developing countries: clinical features, diagnosis, and treatment. Bull World Health Organ 1992; 70:515-26.
19. Hesseling AC, Schaaf HS, Gie RP, Starke JR, Beyers N. A critical review of diagnostic approaches used in the diagnosis of childhood tuberculosis. Int J Tuberc Lung Dis 2002; 6:1038-45. (Pubitemid 36054956)
20. World Health Organization. Guidance for national tuberculosis programmes on the management of tuberculosis in children. Geneva, Switzerland: World Health Organization, 2006.
21. Abebe F, Holm-Hansen C, Wiker HG, Bjune G. Progress in serodiagnosis of Mycobacterium tuberculosis infection. Scand J Immunol 2007; 66:176-91. (Pubitemid 47063204)
22. Laal SaS, Y. Immune-based methods. In: Tuberculosis. Cole ST, Gicquel B, McMurray DN, Eisenach KD, Jacobs WR, eds. 2nd ed. Washington, DC: ASM Press, 2004.
23. Steingart KR, Dendukuri N, Henry M, et al. Performance of purified antigens for serodiagnosis of pulmonary tuberculosis: a meta-analysis. Clin Vaccine Immunol 2009; 16:260-76.
24. Verma RK, Jain A. Antibodies to mycobacterial antigens for diagnosis of tuberculosis. Fems Immunol Med Microbiol 2007; 51:453-61. (Pubitemid 350076155)
25. Steingart KR, Henry M, Laal S, et al. A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. Postgrad Med J 2007; 83:705-12. (Pubitemid 350207516)
26. Steingart KR, Henry M, Laal S, et al. Commercial serological antibody detection tests for the diagnosis of pulmonary tuberculosis: a systematic review. PLoS Med 2007; 4:e202.
27. Talbot EA, Hay Burgess DC, Hone NM, et al. Tuberculosis serodiagnosis in a predominantly HIV-infected population of hospitalized patients with cough, Botswana, 2002. Clin Infect Dis 2004; 39:e1-7.
28. Kassa-Kelembho E, Kassa E, Zandanga G, Service YB, Ignaleamoko A, Talarmin A. Poor performance of a novel serological test for diagnosis of pulmonary tuberculosis in Bangui, Central African Republic. Clin Vaccine Immunol 2006; 13:702-3. (Pubitemid 44032517)
29. World Health Organization. Laboratory-based evaluation of 19 commercially available rapid diagnostic tests for tuberculosis. Geneva, Switzerland: Special Programme for Research & Training in Tropical Diseases (TDR), 2008.
30. Achkar JM, Jenny-Avital E, Yu X, et al. Antibodies against immunodominant antigens of Mycobacterium tuberculosis in subjects with suspected tuberculosis in the United States compared by HIV status. Clin Vaccine Immunol 2010; 17:384-92.
31. Sartain MJ, Slayden RA, Singh KK, Laal S, Belisle JT. Disease state differentiation and identification of tuberculosis biomarkers via native antigen array profiling. Mol Cell Proteomics 2006; 5:2102-3.
32. Samanich K, Belisle JT, Laal S. Homogeneity of antibody responses in tuberculosis patients. Infect Immun 2001; 69:4600-9. (Pubitemid 32574461)
33. Kunnath-Velayudhan S, Salamon H, Wang HY, et al. Dynamic antibody responses to the Mycobacterium tuberculosis proteome. Proc Natl Acad Sci U S A 2010; 107:14703-8.
34. Lyashchenko K, Colangeli R, Houde M, Al Jahdali H, Menzies D, Gennaro ML. Heterogeneous antibody responses in tuberculosis. Infect Immun 1998; 66:3936-40. (Pubitemid 28347858)
35. Lijmer JG, Mol BW, Heisterkamp S, et al. Empirical evidence of design-related bias in studies of diagnostic tests. JAMA 1999; 282:1061-6. (Pubitemid 29436454)
36. Rutjes AW, Reitsma JB, Di Nisio M, Smidt N, van Rijn JC, Bossuyt PM. Evidence of bias and variation in diagnostic accuracy studies. CMAJ 2006; 174:469-76.
37. Hendrickson RC, Douglass JF, Reynolds LD, et al. Mass spectrometric identification of mtb81, a novel serological marker for tuberculosis. J Clin Microbiol 2000; 38:2354-61. (Pubitemid 30414364)
38. Rosenkrands I, Aagaard C,Weldingh K, et al. Identification of Rv0222 from RD4 as a novel serodiagnostic target for tuberculosis. Tuberculosis (Edinb) 2008; 88:335-43.
39. Hoff ST, Abebe M, Ravn P, et al. Evaluation of Mycobacterium tuberculosisdspecific antibody responses in populations with different levels of exposure from Tanzania, Ethiopia, Brazil, and Denmark. Clin Infect Dis 2007; 45:575-82. (Pubitemid 47328637)
40. O'Brien RJ, Talbot EA. The utility of an antibiotic trial for diagnosis of AFB-negative tuberculosis. Int J Tuberc Lung Dis 2003; 7:198. (Pubitemid 36172684)
41. Gennaro ML, Affouf M, Kanaujia GV, Brusasca PN, Mangura B, Reichman L. Antibody markers of incident tuberculosis among HIVinfected adults in the USA: a historical prospective study. Int J Tuberc Lung Dis 2007; 11:624-31. (Pubitemid 46868622)
42. Singh KK, Dong Y, Belisle JT, Harder J, Arora VK, Laal S. Antigens of Mycobacterium tuberculosis recognized by antibodies during incipient, subclinical tuberculosis. Clin Diagn Lab Immunol 2005; 12:354-8. (Pubitemid 41094463)
43. Singh KK, Dong Y, Patibandla SA, McMurray DN, Arora VK, Laal S. Immunogenicity of the Mycobacterium tuberculosis PPE55 (Rv3347c) protein during incipient and clinical tuberculosis. Infect Immun 2005; 73:5004-14. (Pubitemid 41105658)
44. Achkar JM, Dong Y, Holzman RS, et al. Mycobacterium tuberculosis malate synthase- and MPT51-based serodiagnostic assay as an adjunct to rapid identification of pulmonary tuberculosis. Clin Vaccine Immunol 2006; 13:1291-3. (Pubitemid 46768877)
45. Wanchu A, Dong Y, Sethi S, et al. Biomarkers for clinical and incipient tuberculosis: performance in a TB-endemic country. PLoS One 2008; 3:e2071.
46. Corbett EL, Charalambous S, Moloi VM, et al. Human immunodeficiency virus and the prevalence of undiagnosed tuberculosis in African gold miners. Am J Respir Crit Care Med 2004; 170:673-9. (Pubitemid 39202210)
47. Mtei L, Matee M, Herfort O, et al. High rates of clinical and subclinical tuberculosis among HIV-infected ambulatory subjects in Tanzania. Clin Infect Dis 2005; 40:1500-7. (Pubitemid 40628639)
48. Haramati LB, Jenny-Avital ER, Alterman DD. Effect of HIV status on chest radiographic and CT findings in patients with tuberculosis. Clin Radiol 1997; 52:31-5.
49. Pitchenik AE, Rubinson HA. The radiographic appearance of tuberculosis in patients with the acquired immune deficiency syndrome (AIDS) and pre-AIDS. Am Rev Respir Dis 1985; 131:393-6. (Pubitemid 15133600)
50. Di Perri G, Cazzadori A, Vento S, et al. Comparative histopathological study of pulmonary tuberculosis in human immunodeficiency virusinfected and non-infected patients. Tuber Lung Dis 1996; 77:244-9. (Pubitemid 26261312)
51. Schijman AG, Losso MH, Montoto M, Saez CB, Smayevsky J, Benetucci JA. Prospective evaluation of in-house polymerase chain reaction for diagnosis of mycobacterial diseases in patients with HIV infection and lung infiltrates. Int J Tuberc Lung Dis 2004; 8:106-13. (Pubitemid 38120713)
52. Rebollo MJ, San Juan Garrido R, Folgueira D, et al. Blood and urine samples as useful sources for the direct detection of tuberculosis by polymerase chain reaction. Diagn Microbiol Infect Dis 2006; 56:141-6. (Pubitemid 44486627)
53. Condos R, McClune A, Rom WN, Schluger NW. Peripheral-bloodbased PCR assay to identify patients with active pulmonary tuberculosis. Lancet 1996; 347:1082-5. (Pubitemid 26118897)
54. Lane HC, Masur H, Edgar LC, Whalen G, Rook AH, Fauci AS. Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome. N Engl J Med 1983; 309:453-8. (Pubitemid 13041485)
55. Yarchoan R, Redfield RR, Broder S. Mechanisms of B cell activation in patients with acquired immunodeficiency syndrome and related disorders. Contribution of antibody-producing B cells, of Epstein-Barr virus-infected B cells, and of immunoglobulin production induced by human T cell lymphotropic virus, type III/lymphadenopathy-associated virus. J Clin Invest 1986; 78:439-47. (Pubitemid 16074081)
56. Lalvani A. Diagnosing tuberculosis infection in the 21st century: new tools to tackle an old enemy. Chest 2007; 131:1898-06. (Pubitemid 46981652)
57. Dosanjh DP, Hinks TS, Innes JA, et al. Improved diagnostic evaluation of suspected tuberculosis. Ann Intern Med 2008; 148:325-36. (Pubitemid 351665463)
58. Wilkinson KA, Wilkinson RJ, Pathan A, et al. Ex vivo characterization of early secretory antigenic target 6-specific T cells at sites of active disease in pleural tuberculosis. Clin Infect Dis 2005; 40:184-7. (Pubitemid 40053478)
59. Jafari C, Ernst M, Kalsdorf B, et al. Rapid diagnosis of smear-negative tuberculosis by bronchoalveolar lavage enzyme-linked immunospot. Am J Respir Crit Care Med 2006; 174:1048-54. (Pubitemid 44684455)
60. Jafari C, Ernst M, Strassburg A, et al. Local immunodiagnosis of pulmonary tuberculosis by enzyme-linked immunospot. Eur Respir J 2008; 31:261-5.
61. Mazurek GH,Weis SE,Moonan PK, et al. Prospective comparison of the tuberculin skin test and 2 whole-blood interferon-gamma release assays in persons with suspected tuberculosis. Clin Infect Dis 2007; 45:837-45. (Pubitemid 47580374)
62. Nemeth J, Winkler HM, Zwick RH, et al. Recruitment of Mycobacterium tuberculosis specific CD41 T cells to the site of infection for diagnosis of active tuberculosis. J Intern Med 2009; 265:163-8.
63. Losi M, Bossink A, Codecasa L, et al. Use of a T-cell interferon-gamma release assay for the diagnosis of tuberculous pleurisy. Eur Respir J 2007; 30:1173-9. (Pubitemid 351194766)
64. Kosters K, Nau R, Bossink A, et al. Rapid diagnosis of CNS tuberculosis by a T-cell interferon-gamma release assay on cerebrospinal fluid mononuclear cells. Infection 2008; 36:597-600.
65. Dheda K, van Zyl-Smit RN, Meldau R, et al. Quantitative lung T cell responses aid the rapid diagnosis of pulmonary tuberculosis. Thorax 2009; 64:847-53.
66. Dheda K, van Zyl-Smit RN, Sechi LA, et al. Utility of quantitative T-cell responses versus unstimulated interferon-{gamma} for the diagnosis of pleural tuberculosis. Eur Respir J 2009; 34:1118-26.
67. Lange C, Hellmich B, Ernst M, Ehlers S. Rapid immunodiagnosis of tuberculosis in a woman receiving anti-TNF therapy. Nat Clin Pract Rheumatol 2007; 3:528-34. (Pubitemid 47351398)
68. Jafari C, Thijsen S, Sotgiu G, et al. Bronchoalveolar lavage enzymelinked immunospot for a rapid diagnosis of tuberculosis: a Tuberculosis Network European Trials group study. Am J Respir Crit Care Med 2009; 180:666-73.
69. Ariga H, Kawabe Y, Nagai H, et al. Diagnosis of active tuberculous serositis by antigen-specific interferon-gamma response of cavity fluid cells. Clin Infect Dis 2007; 45:1559-67. (Pubitemid 351411839)
70. Baba K, Sornes S, Hoosen AA, et al. Evaluation of immune responses in HIV infected patients with pleural tuberculosis by the QuantiFERON TB-Gold interferon-gamma assay. BMC Infect Dis 2008; 8:35.
71. Chegou NN, Walzl G, Bolliger CT, Diacon AH, van den Heuvel MM. Evaluation of adapted whole-blood interferon-gamma release assays for the diagnosis of pleural tuberculosis. Respiration 2008; 76:131-8.
72. Kim SH, Cho OH, Park SJ, et al. Diagnosis of abdominal tuberculosis by T-cell-based assays on peripheral blood and peritoneal fluid mononuclear cells. J Infect 2009; 59:409-15.
73. Patel VB, Singh R, Connolly C, et al. Cerebrospinal T-cell responses aid in the diagnosis of tuberculous meningitis in a human immunodeficiency virus- and tuberculosis-endemic population. Am J Respir Crit Care Med 2010; 182:569-77.
74. Kim SH, Chu K, Choi SJ, et al. Diagnosis of central nervous system tuberculosis by T-cell-based assays on peripheral blood and cerebrospinal fluid mononuclear cells. Clin Vaccine Immunol 2008; 15:1356-62.
75. Murakami S, Takeno M, Oka H, et al. Diagnosis of tuberculous meningitis due to detection of ESAT-6-specific gamma interferon production in cerebrospinal fluid enzyme-linked immunospot assay. Clin Vaccine Immunol 2008; 15:897-9. (Pubitemid 351967036)
76. Thomas MM, Hinks TS, Raghuraman S, et al. Rapid diagnosis of Mycobacterium tuberculosis meningitis by enumeration of cerebrospinal fluid antigen-specific T-cells. Int J Tuberc Lung Dis 2008; 12:651-7. (Pubitemid 351846763)
77. Phypers M, Harris T, Power C. CNS tuberculosis: a longitudinal analysis of epidemiological and clinical features. Int J Tuberc Lung Dis 2006; 10:99-103. (Pubitemid 43266285)
78. Peto HM, Pratt RH, Harrington TA, LoBue PA, Armstrong LR. Epidemiology of extrapulmonary tuberculosis in the United States, 1993-2006. Clin Infect Dis 2009; 49:1350-7.
79. Elder NC. Extrapulmonary tuberculosis. A review. Arch Fam Med 1992; 1:91-8.
80. Ozbay B, Uzun K. Extrapulmonary tuberculosis in high prevalence of tuberculosis and low prevalence of HIV. Clin Chest Med 2002; 23:351-4. (Pubitemid 34651330)
81. Karstaedt AS, Valtchanova S, Barriere R, Crewe-Brown HH. Tuberculous meningitis in South African urban adults. QJM 1998; 91:743-7. (Pubitemid 28508620)
82. Berenguer J, Moreno S, Laguna F, et al. Tuberculous meningitis in patients infected with the human immunodeficiency virus. N Engl J Med 1992; 326:668-72.
83. Lucas SB, Hounnou A, Peacock C, et al. The mortality and pathology of HIV infection in a west African city. AIDS 1993; 7:1569-79. (Pubitemid 24008849)
84. Vinnard C, Macgregor RR. Tuberculous meningitis in HIV-infected individuals. Curr HIV/AIDS Rep 2009; 6:139-45.
85. Rock RB, Olin M, Baker CA, Molitor TW, Peterson PK. Central nervous system tuberculosis: pathogenesis and clinical aspects. Clin Microbiol Rev 2008; 21:243-61, table of contents. (Pubitemid 351555506)
86. Pai M, Minion J, Sohn H, Zwerling A, Perkins MD. Novel and improved technologies for tuberculosis diagnosis: progress and challenges. Clin Chest Med 2009; 30:701-16, viii.
87. Peter J, Green C, HoelscherM,Mwaba P, Zumla A, Dheda K. Urine for the diagnosis of tuberculosis: current approaches, clinical applicability, and new developments. Curr Opin Pulm Med 2010; 16:262-70.
88. Kashino SS, Pollock N, Napolitano DR, Rodrigues V Jr and Campos- Neto A. Identification and characterization of Mycobacteriumtuberculosis antigens in urine of patients with active pulmonary tuberculosis: an innovative and alternative approach of antigen discovery of useful microbial molecules. Clin Exp Immunol 2008; 153:56-62. (Pubitemid 351809340)
89. Napolitano DR, Pollock N, Kashino SS, Rodrigues V Jr and Campos- Neto A. Identification of Mycobacterium tuberculosis ornithine carboamyltransferase in urine as a possible molecular marker of active pulmonary tuberculosis. Clin Vaccine Immunol 2008; 15: 638-43. (Pubitemid 351967039)
90. Choudhry V, Saxena RK. Detection of Mycobacterium tuberculosis antigens in urinary proteins of tuberculosis patients. Eur J Clin Microbiol Infect Dis 2002; 21:1-5. (Pubitemid 34158499)
91. Briken V, Porcelli SA, Besra GS, Kremer L. Mycobacterial lipoarabinomannan and related lipoglycans: frombiogenesis tomodulation of the immune response.Mol Microbiol 2004; 53:391-403. (Pubitemid 38998163)
92. Hamasur B, Bruchfeld J, Haile M, et al. Rapid diagnosis of tuberculosis by detection of mycobacterial lipoarabinomannan in urine. J Microbiol Methods 2001; 45:41-52. (Pubitemid 32268707)
93. Boehme C, Molokova E, Minja F, et al. Detection of mycobacterial lipoarabinomannan with an antigen-capture ELISA in unprocessed urine of Tanzanian patients with suspected tuberculosis. Trans R Soc Trop Med Hyg 2005; 99:893-900. (Pubitemid 41511449)
94. Tessema TA, Hamasur B, Bjun G, Svenson S, Bjorvatn B. Diagnostic evaluation of urinary lipoarabinomannan at an Ethiopian tuberculosis centre. Scand J Infect Dis 2001; 33:279-84. (Pubitemid 32366653)
95. Lawn SD, Edwards DJ, Kranzer K, Vogt M, Bekker LG, Wood R. Urine lipoarabinomannan assay for tuberculosis screening before antiretroviral therapy diagnostic yield and association with immune reconstitution disease. AIDS 2009; 23:1875-80.
96. Mutetwa R, Boehme C, Dimairo M, et al. Diagnostic accuracy of commercial urinary lipoarabinomannan detection in African tuberculosis suspects and patients. Int J Tuberc Lung Dis 2009; 13: 1253-9.
97. Reither K, Saathoff E, Jung J, et al. Low sensitivity of a urine LAMELISA in the diagnosis of pulmonary tuberculosis. BMC Infect Dis 2009; 9:141.
98. Daley P, Michael JS, Hmar P, et al. Blinded evaluation of commercial urinary lipoarabinomannan for active tuberculosis: a pilot study. Int J Tuberc Lung Dis 2009; 13:989-95.
99. Shah M, Variava E, Holmes CB, et al. Diagnostic accuracy of a urine lipoarabinomannan test for tuberculosis in hospitalized patients in a High HIV prevalence setting. J Acquir Immune Defic Syndr 2009; 52:145-51.
100. Dheda K, Davids V, Lenders L, et al. Clinical utility of a commercial LAM-ELISA assay for TB diagnosis in HIV-infected patients using urine and sputum samples. PLoS One 2010; 5:e9848.
101. Reid MJ, Shah NS. Approaches to tuberculosis screening and diagnosis in people with HIV in resource-limited settings. Lancet Infect Dis 2009; 9:173-84.
102. Elliott AM, Halwiindi B, Hayes RJ, et al. The impact of human immunodeficiency virus on presentation and diagnosis of tuberculosis in a cohort study in Zambia. J Trop Med Hyg 1993; 96:1-11.
103. Lawn SD, Butera ST, Shinnick TM. Tuberculosis unleashed: the impact of human immunodeficiency virus infection on the host granulomatous response to Mycobacterium tuberculosis. Microbes Infect 2002; 4:635-46. (Pubitemid 34614552)
104. Lawn SD, Harries AD, Anglaret X, Myer L, Wood R. Early mortality among adults accessing antiretroviral treatment programmes in sub- Saharan Africa. AIDS 2008; 22:1897-908.
105. Chow F, Espiritu N, Gilman RH, et al. La cuerda dulceda tolerability and acceptability study of a novel approach to specimen collection for diagnosis of paediatric pulmonary tuberculosis. BMC Infect Dis 2006; 6:67.
106. Vargas D, Garcia L, Gilman RH, et al. Diagnosis of sputum-scarce HIV-associated pulmonary tuberculosis in Lima, Peru. Lancet 2005; 365:150-2. (Pubitemid 40091805)
107. Al Zahrani K, Al Jahdali H, Poirier L, Rene P, Menzies D. Yield of smear, culture and amplification tests from repeated sputum induction for the diagnosis of pulmonary tuberculosis. Int J Tuberc Lung Dis 2001; 5:855-60. (Pubitemid 32843680)
108. Atiq-ur-Rehman M, Naseem A, Hussain T. Comparison of diagnostic yield of AFB with sputum induction to spontaneous sputum examination in suspected pulmonary tuberculosis. J Coll Physicians Surg Pak 2009; 19:506-9.
109. Conde MB, Loivos AC, Rezende VM, et al. Yield of sputum induction in the diagnosis of pleural tuberculosis. Am J Respir Crit Care Med 2003; 167:723-5. (Pubitemid 36801748)
110. Fletcher D, Bellin E, Lin YC, Shuter J. Predictive value of acid-fast smears of sputum obtained by expectoration versus induction or bronchoalveolar lavage in patients with tuberculosis. Clin Infect Dis 1995; 20:1575-6.
111. Fujita A, Murata K, Takamori M. Novel method for sputum induction using the lung flute in patients with suspected pulmonary tuberculosis. Respirology 2009; 14:899-902.
112. Gatner EM, Gartig D, Kleeberg HH. Sputum induction by saline aerosol. S Afr Med J 1977; 51:279-80. (Pubitemid 8053581)
113. Hartung TK, Maulu A, Nash J, Fredlund VG. Suspected pulmonary tuberculosis in rural South Africa-sputum induction as a simple diagnostic tool? S Afr Med J 2002; 92:455-8. (Pubitemid 34716590)
114. Parry CM, Kamoto O, Harries AD, et al. The use of sputum induction for establishing a diagnosis in patients with suspected pulmonary tuberculosis in Malawi. Tuber Lung Dis 1995; 76:72-6.
115. Brown M, Varia H, Bassett P, Davidson RN, Wall R, Pasvol G. Prospective study of sputum induction, gastric washing, and bronchoalveolar lavage for the diagnosis of pulmonary tuberculosis in patients who are unable to expectorate. Clin Infect Dis 2007; 44:1415-20. (Pubitemid 46801582)
116. Carr DT, Karlson AG, Stilwell GG. A comparison of cultures of induced sputum and gastric washings in the diagnosis of tuberculosis. Mayo Clin Proc 1967; 42:23-5.
117. Dickson SJ, Brent A, Davidson RN, Wall R. Comparison of bronchoscopy and gastric washings in the investigation of smear-negative pulmonary tuberculosis. Clin Infect Dis 2003; 37:1649-53. (Pubitemid 37549952)
118. Laven GT. Diagnosis of tuberculosis in children using fluorescence microscopic examination of gastric washings. Am Rev Respir Dis 1977; 115:743-9. (Pubitemid 8102620)
119. Uskul BT, Turker H, Kant A, Partal M. Comparison of bronchoscopic washing and gastric lavage in the diagnosis of smear-negative pulmonary tuberculosis. South Med J 2009; 102:154-8.
120. Anderson C, Inhaber N, Menzies D. Comparison of sputum induction with fiber-optic bronchoscopy in the diagnosis of tuberculosis. Am J Respir Crit Care Med 1995; 152:1570-4. (Pubitemid 3002096)
121. Conde MB, Soares SL, Mello FC, et al. Comparison of sputum induction with fiberoptic bronchoscopy in the diagnosis of tuberculosis: experience at an acquired immune deficiency syndrome reference center in Rio de Janeiro, Brazil. Am J Respir Crit Care Med 2000; 162:2238-40. (Pubitemid 32051694)
122. Ganguly KC, Hiron MM, Mridha ZU, et al. Comparison of sputum induction with broncho-alveolar lavage in the diagnosis of smearnegative pulmonary tuberculosis. Mymensingh Med J 2008; 17:115-23.
123. Larson JL, Ridzon R, Hannan MM. Sputum induction versus fiberoptic bronchoscopy in the diagnosis of tuberculosis. Am J Respir Crit Care Med 2001; 163:1279-80. (Pubitemid 32378474)
124. Li LM, Bai LQ, Yang HL, et al. Sputum induction to improve the diagnostic yield in patients with suspected pulmonary tuberculosis. Int J Tuberc Lung Dis 1999; 3:1137-9.
125. Menzies D. Sputum induction: simpler, cheaper, and saferdbut is it better? Am J Respir Crit Care Med 2003; 167:676-7.
126. Jensen PA, Lambert LA, Iademarco MF, Ridzon R. Guidelines for preventing the transmission of Mycobacterium tuberculosis in healthcare settings, 2005. MMWR Recomm Rep 2005; 54:1-104.
127. Leong AB. On risks of fiberoptic bronchoscopy and bronchoalveolar lavage (BAL). Pediatr Pulmonol 1988; 4:128.
128. McWilliams T, Wells AU, Harrison AC, Lindstrom S, Cameron RJ, Foskin E. Induced sputum and bronchoscopy in the diagnosis of pulmonary tuberculosis. Thorax 2002; 57:1010-4. (Pubitemid 35440758)
129. Morse M, Kessler J, Albrecht S, et al. Induced sputum improves the diagnosis of pulmonary tuberculosis in hospitalized patients in Gaborone, Botswana. Int J Tuberc Lung Dis 2008; 12:1279-85.
130. Mwinga A. Challenges and hope for the diagnosis of tuberculosis in infants and young children. Lancet 2005; 365:97-8. (Pubitemid 40091787)
131. Bell D, Leckie V, McKendrick M. Use of the induced sputum procedure in the investigation of smear-negative pulmonary tuberculosis. Clin Infect Dis 2004; 38:1504-5. (Pubitemid 38668601)
132. Jones JE. String test for diagnosing giardiasis. Am Fam Physician 1986; 34:123-6. (Pubitemid 16045447)
133. Beal CB, Viens P, Grant RG, Hughes JM. A new technique for sampling duodenal contents: demonstration of upper small-bowel pathogens. Am J Trop Med Hyg 1970; 19:349-52.
134. Gilman RH, Islam S, Rabbani H, Ghosh H. Identification of gallbladder typhoid carriers by a string device. Lancet 1979; 1:795-6. (Pubitemid 9150533)
135. Bae WH, Salas A, Brady MF, et al. Reducing the string test intragastric downtime for detection of Mycobacterium tuberculosis. Int J Tuberc Lung Dis 2008; 12:1436-40.
136. Das P, Horton R. Tuberculosis-time to accelerate progress. The Lancet 2010; 375:1755-7.
137. Marais BJ, Hesseling AC, Gie RP, Schaaf HS, Beyers N. The burden of childhood tuberculosis and the accuracy of community-based surveillance data. Int J Tuberc Lung Dis 2006; 10:259-63.
138. Cruz AT, Starke JR. Pediatric tuberculosis. Pediatrics Rev 2010; 31:13-26.
139. Wright CA, Hesseling A, Bamford C, Burgess SM, Warren RM,Marais BJ. Fine-needle aspiration biopsy: a first-line diagnostic procedure in paediatric tuberculosis suspects with peripheral lymphadenopathy. Int J Tuberc Lung Dis 2009; 13:1373-9.
140. Marais BJ, Gie RP, Schaaf HS, Hesseling AC, Enarson DA, Beyers N. The spectrum of disease in children treated for tuberculosis in a highly endemic area. Int J Tuberc Lung Dis 2006; 10:732-8. (Pubitemid 44031385)
141. Leiman G. The registered nurse as aspirator: experience in a busy cytopathology unit. Acta Cytol 1995; 39:1010.
142. Wright CA, Warren RM, Marais BJ. Fine needle aspiration biopsy: an undervalued diagnostic modality in paediatric mycobacterial disease [Review article]. Int J Tuberc Lung Dis 2009; 13:1467-75.
143. Wright CA, Bamford C, Prince Y, et al. Mycobacterial transport medium for routine culture of fine needle aspiration biopsies. Arch Dis Child 2010; 95:48-50.
144. Marais BJ, Brittle W, Painczyk K, et al. Use of light-emitting diode fluorescence microscopy to detect acid-fast bacilli in sputum. Clin Infect Dis 2008; 47:203-7. (Pubitemid 351920621)
145. Wright CA, van der BurgM, Geiger D, Noordzij JG, Burgess SM,Marais BJ. Diagnosingmycobacterial lymphadenitis in children using fine needle aspiration biopsy: cytomorphology, ZN staining and autofluorescenced making more of less. Diagn Cytopathol 2008; 36:245-51. (Pubitemid 351458183)
146. Daley P, Thomas S, Pai M. Nucleic acid amplification tests for the diagnosis of tuberculous lymphadenitis: a systematic review. Int J Tuberc Lung Dis 2007; 11:1166-76. (Pubitemid 350146296)
147. Wright CA, Hoek KGP, Marais BJ, van Helden P, Warren RM. Combining fine-needle aspiration biopsy (FNAB) and high-resolution melt analysis to reduce diagnostic delay in mycobacterial lymphadenitis. Diagn Cytopathol 2010; 38:482-8.