An immune function assay predicts post-transplant recurrence in patients with hepatocellular carcinoma

Journal of Cancer Research and Clinical Oncology

Volumn 137, Issue 10, 2011, Pages 1445-1453

  Cheng, Jian Wen ^a,b   Shi, Ying Hong ^a   Fan, Jia ^a,b   Huang, Xiao Wu ^a,b   Qiu, Shuang Jian ^a   Xiao, Yong Sheng ^a,b   Wang, Zheng ^a,b   Dai, Zhi ^b   Tang, Zhao You ^a,b   Zhou, Jian ^a,b  

^a FUDAN UNIVERSITY   (China)

^b Shanghai Key Laboratory of Organ Transplantation   (China)

Author keywords

Hepatocellular carcinoma; Immune function assay; Liver transplantation; Recurrence

Indexed keywords

ADENOSINE TRIPHOSPHATE; CORTICOSTEROID; TACROLIMUS;

ACUTE GRAFT REJECTION; ADULT; BLOOD SAMPLING; CANCER SURVIVAL; CD4+ T LYMPHOCYTE; CLINICAL EFFECTIVENESS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE FREE SURVIVAL; FEMALE; GRAFT RECIPIENT; HUMAN; IMMUNOASSAY; IMMUNOLOGICAL MONITORING; IMMUNOREACTIVITY; INFECTION RISK; LIVER CELL CARCINOMA; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE COMPLICATION; PREDICTION; PRIORITY JOURNAL; RECURRENT CANCER; REVIEW; RISK ASSESSMENT;

ADENOSINE TRIPHOSPHATE; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, HEPATOCELLULAR; FEMALE; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LIVER NEOPLASMS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; PROPORTIONAL HAZARDS MODELS;

EID: 80054762018     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-011-1014-0     Document Type: Review

References (26)

1. SM Bhorade K Janata WT Vigneswaran CG Alex ER Garrity 2008 Cylex ImmuKnow assay levels are lower in lung transplant recipients with infection J Heart Lung Transplant 27 9 990 994 10.1016/j.healun.2008.06.005 18765191 10.1016/j.healun.2008.06.005
2. AP de Souza C Bonorino 2009 Tumor immunosuppressive environment: effects on tumor-specific and nontumor antigen immune responses Expert Rev Anticancer Ther 9 9 1317 1332 10.1586/era.09.88 19761435 10.1586/era.09.88
3. NL Dirks B Huth CR Yates B Meibohm 2004 Pharmacokinetics of immunosuppressants: a perspective on ethnic differences Int J Clin Pharmacol Ther 42 12 701 718 15624287 1:CAS:528:DC%2BD2MXhtVCjsw%3D%3D (Pubitemid 39625130)
4. JW Gray 2003 Evidence emerges for early metastasis and parallel evolution of primary and metastatic tumors Cancer Cell 4 1 4 6 12892707 10.1016/S1535-6108(03)00167-3 1:CAS:528:DC%2BD3sXmt1SltL8%3D (Pubitemid 36908832)
5. S Gupta JD Mitchell DW Markham PP Mammen PC Patel PA Kaiser P Stastny WS Ring JM Dimaio MH Drazner 2008 Utility of the Cylex assay in cardiac transplant recipients J Heart Lung Transplant 27 8 817 822 10.1016/j.healun.2008.05.014 18656792 10.1016/j.healun.2008.05.014
6. Hashimoto K, Miller C, Hirose K, Diago T, Aucejo F, Quintini C, Eghtesad B, Corey R, Yerian L, Lopez R, Zein N, Fung J (2009) Measurement of CD4+ T-cell function in predicting allograft rejection and recurrent hepatitis C after liver transplantation. Clin Transplant. doi: 10.1111/j.1399-0012.2009.01169.x
7. S Husain K Raza JM Pilewski D Zaldonis M Crespo Y Toyoda K Shutt K Spichty C Bentlejewski DL Pakstis ME Carey KR McCurry A Zeevi 2009 Experience with immune monitoring in lung transplant recipients: correlation of low immune function with infection Transplantation 87 12 1852 1857 10.1097/TP. 0b013e3181a75ad2 19543064 10.1097/TP.0b013e3181a75ad2 1:CAS:528: DC%2BD1MXnsFyht7s%3D
8. R Kowalski D Post MC Schneider J Britz J Thomas M Deierhoi A Lobashevsky R Redfield E Schweitzer A Heredia E Reardon C Davis C Bentlejewski J Fung R Shapiro A Zeevi 2003 Immune cell function testing: an adjunct to therapeutic drug monitoring in transplant patient management Clin Transplant 17 2 77 88 12709071 10.1034/j.1399-0012.2003.00013.x (Pubitemid 36833776)
9. RJ Kowalski DR Post RB Mannon A Sebastian HI Wright G Sigle J Burdick KA Elmagd A Zeevi M Lopez-Cepero JA Daller HA Gritsch EF Reed J Jonsson D Hawkins JA Britz 2006 Assessing relative risks of infection and rejection: a meta-analysis using an immune function assay Transplantation 82 5 663 668 10.1097/01.tp.0000234837.02126.70 16969290 10.1097/01.tp.0000234837.02126.70 (Pubitemid 44395237)
10. JM Llovet J Fuster J Bruix 2004 The Barcelona approach: diagnosis, staging, and treatment of hepatocellular carcinoma Liver Transpl 10 2 Suppl 1 S115 S120 10.1002/lt.20034 14762851 10.1002/lt.20034
11. V Mazzaferro E Regalia R Doci S Andreola A Pulvirenti F Bozzetti F Montalto M Ammatuna A Morabito L Gennari 1996 Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis N Engl J Med 334 11 693 699 8594428 10.1056/NEJM199603143341104 1:STN:280: DyaK287nsFWltw%3D%3D (Pubitemid 26079803)
12. XM Mueller 2004 Drug immunosuppression therapy for adult heart transplantation. Part 1: immune response to allograft and mechanism of action of immunosuppressants Ann Thorac Surg 77 1 354 362 14726104 10.1016/j.athoracsur. 2003.07.006 (Pubitemid 38130055)
13. GW Neff N Kemmer T Kaiser V Zacharias N Majoras K Safdar 2007 Outcomes in adult and pediatric liver transplantation among various ethnic groups Transplant Proc 39 10 3204 3206 10.1016/j.transproceed.2007.09.031 18089354 10.1016/j.transproceed.2007.09.031 1:STN:280:DC%2BD2sjltF2rtA%3D%3D (Pubitemid 350251498)
14. S Ostrand-Rosenberg 2008 Immune surveillance: a balance between protumor and antitumor immunity Curr Opin Genet Dev 18 1 11 18 10.1016/j.gde.2007.12.007 18308558 10.1016/j.gde.2007.12.007 1:CAS:528:DC%2BD1cXmsVartLc%3D (Pubitemid 351694442)
15. DM Parkin F Bray J Ferlay P Pisani 2005 Global cancer statistics, 2002 CA Cancer J Clin 55 2 74 108 15761078 10.3322/canjclin.55.2.74 (Pubitemid 40372904)
16. I Perry J Neuberger 2005 Immunosuppression: towards a logical approach in liver transplantation Clin Exp Immunol 139 1 2 10 10.1111/j.1365-2249.2005. 02662.x 15606606 10.1111/j.1365-2249.2005.02662.x 1:CAS:528:DC%2BD2MXhtFWmsLs%3D (Pubitemid 40066121)
17. JW Rossano SW Denfield JJ Kim JF Price JL Jefferies JA Decker EO Smith SK Clunie JA Towbin WJ Dreyer 2009 Assessment of the Cylex ImmuKnow cell function assay in pediatric heart transplant patients J Heart Lung Transplant 28 1 26 31 10.1016/j.healun.2008.10.001 19134527 10.1016/j.healun.2008.10.001
18. P Rovira L Mascarell P Truffa-Bachi 2000 The impact of immunosuppressive drugs on the analysis of T cell activation Curr Med Chem 7 7 673 692 10702633 1:CAS:528:DC%2BD3cXjvFCmtLg%3D (Pubitemid 30366636)
19. G Serban V Whittaker J Fan Z Liu K Manga M Khan K Kontogianni A Padmanabhan D Cohen N Suciu-Foca L Ratner AI Colovai 2009 Significance of immune cell function monitoring in renal transplantation after Thymoglobulin induction therapy Hum Immunol 70 11 882 890 10.1016/j.humimm.2009.07.027 19664673 10.1016/j.humimm.2009.07.027 1:CAS:528:DC%2BD1MXht1Ons73J
20. JE Talmadge 2007 Clonal selection of metastasis within the life history of a tumor Cancer Res 67 24 11471 11475 10.1158/0008-5472.CAN-07-2496 18089772 10.1158/0008-5472.CAN-07-2496 1:CAS:528:DC%2BD2sXhsVCjs7zK
21. R Venkataramanan LM Shaw L Sarkozi R Mullins J Pirsch G MacFarlane D Scheller D Ersfeld M Frick WE Fitzsimmons M Virji A Jain KL Brayman A Shaked 2001 Clinical utility of monitoring tacrolimus blood concentrations in liver transplant patients J Clin Pharmacol 41 5 542 551 11361051 10.1177/ 00912700122010429 1:CAS:528:DC%2BD3MXjvVaksbc%3D (Pubitemid 32381872)
22. M Vivarelli A Cucchetti F Piscaglia G La Barba L Bolondi A Cavallari AD Pinna 2005 Analysis of risk factors for tumor recurrence after liver transplantation for hepatocellular carcinoma: key role of immunosuppression Liver Transpl 11 5 497 503 10.1002/lt.20391 15838913 10.1002/lt.20391 (Pubitemid 40704060)
23. M Vivarelli A Cucchetti G La Barba M Ravaioli M Del Gaudio A Lauro GL Grazi AD Pinna 2008 Liver transplantation for hepatocellular carcinoma under calcineurin inhibitors: reassessment of risk factors for tumor recurrence Ann Surg 248 5 857 862 10.1097/SLA.0b013e3181896278 18948815 10.1097/SLA. 0b013e3181896278
24. F Xue J Zhang L Han Q Li N Xu T Zhou Z Xi Y Wu Q Xia 2010 Immune cell functional assay in monitoring of adult liver transplantation recipients with infection Transplantation 89 5 620 626 10.1097/TP.0b013e3181c690fa 20010326 10.1097/TP.0b013e3181c690fa
25. QH Ye LX Qin M Forgues P He JW Kim AC Peng R Simon Y Li AI Robles Y Chen ZC Ma ZQ Wu SL Ye YK Liu ZY Tang XW Wang 2003 Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning Nat Med 9 4 416 423 10.1038/nm843 12640447 10.1038/nm843 1:CAS:528:DC%2BD3sXisVOmu7o%3D (Pubitemid 36460075)
26. MA Zimmerman RM Ghobrial MJ Tong JR Hiatt AM Cameron J Hong RW Busuttil 2008 Recurrence of hepatocellular carcinoma following liver transplantation: a review of preoperative and postoperative prognostic indicators Arch Surg 143 2 182 188 10.1001/archsurg.2007.39 18283144 10.1001/archsurg.2007.39 discussion 188 (Pubitemid 351281631)