Thalidomide modulates Mycobacterium leprae-induced NF-κB pathway and lower cytokine response

European Journal of Pharmacology

Volumn 670, Issue 1, 2011, Pages 272-279

  Hernandez, Maristela De Oliveira ^a   Fulco, Tatiana De Oliveira ^a   Pinheiro, Roberta Olmo ^a   Pereira, Renata De Meirelles Santos ^b   Redner, Paulo ^a,b   Sarno, Euzenir Nunes ^a   Lopes, Ulisses Gazos ^b   Sampaio, Elizabeth Pereira ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Leprosy; M. leprae; NF B; Thalidomide; TNF

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEPROSTATIC AGENT; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; THALIDOMIDE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BIOACCUMULATION; CELL ACTIVATION; CELL NUCLEUS; CELL STIMULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; LEPROSY; MALE; MONOCYTE; MYCOBACTERIUM LEPRAE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TRANSCRIPTION INITIATION;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL NUCLEUS; DNA; ENZYME ACTIVATION; FEMALE; HUMANS; LEPROSTATIC AGENTS; LEPROSY; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYCOBACTERIUM LEPRAE; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION; THALIDOMIDE; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80054761681     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.08.046     Document Type: Article

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