Effect of the leukotriene A4 hydrolase aminopeptidase augmentor 4-methoxydiphenylmethane in a pre-clinical model of pulmonary emphysema

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 22, 2011, Pages 6746-6750

  De Oliveira, Eliseu O ^a   Wang, Kan ^a   Kong, Hye Sik ^a   Kim, Suhyon ^b   Miessau, Matthew ^a   Snelgrove, Robert J ^c   Shim, Y Michael ^b   Paige, Mikell ^a  

^a GEORGETOWN UNIVERSITY   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Aminopeptidase; COPD; Emphysema; Leukotriene A4 hydrolase; LTB4; Murine model

Indexed keywords

4 METHOXYDIPHENYLMETHANE; AMINOPEPTIDASE; ELASTASE; LEUKOTRIENE A4 HYDROLASE; TOLUENE; UNCLASSIFIED DRUG; 4-METHOXYDIPHENYLMETHANE; BENZHYDRYL DERIVATIVE; EPOXIDE HYDROLASE; PANCREATIC ELASTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DOSE ESCALATION; ENZYME ACTIVITY; LUNG EMPHYSEMA; MOUSE; NONHUMAN; ANIMAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG EFFECT; LUNG; METABOLISM; PATHOLOGY;

MURINAE;

ANIMALS; BENZHYDRYL COMPOUNDS; EPOXIDE HYDROLASES; LUNG; MICE; PANCREATIC ELASTASE; PULMONARY EMPHYSEMA;

EID: 80054760140     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.09.048     Document Type: Article

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