Degradation improves tissue formation in (Un)loaded chondrocyte-laden hydrogels

Clinical Orthopaedics and Related Research

Volumn 469, Issue 10, 2011, Pages 2725-2734

  Roberts, Justine J ^a   Nicodemus, Garret D ^a   Greenwald, Eric C ^a   Bryant, Stephanie J ^a  

^a University of Colorado at Boulder   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; COLLAGEN TYPE 2; COLLAGEN TYPE 6; COPOLYMER; DECORIN; GLYCOSAMINOGLYCAN; LINK PROTEIN; OLIGO(LACTIC ACID) ETHYLENE GLYCOL OLIGO(LACTIC ACID) COPOLYMER; UNCLASSIFIED DRUG;

ANIMAL CELL; BIOMECHANICS; CARBOHYDRATE ANALYSIS; CARTILAGE; CARTILAGE CELL; CONFERENCE PAPER; DEGRADATION; HYDROGEL; MECHANICAL STRESS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; TISSUE DISTRIBUTION; TISSUE ENGINEERING;

EID: 80054753213     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1007/s11999-011-1823-0     Document Type: Conference Paper

References (39)

1. KS Anseth AT Metters SJ Bryant PJ Martens JH Elisseeff CN Bowman 2002 In situ forming degradable networks and their application in tissue engineering and drug delivery J Control Release. 78 199 209 11772461 10.1016/S0168-3659(01) 00500-4 1:CAS:528:DC%2BD3MXptlaitrk%3D (Pubitemid 34081865)
2. OM Babalola LJ Bonassar 2009 Parametric finite element analysis of physical stimuli resulting from mechanical stimulation of tissue engineered cartilage J Biomech Eng. 131 061014 19449968 10.1115/1.3128672
3. AM Bhosale JB Richardson 2008 Articular cartilage: structure, injuries and review of management Br Med Bull. 87 77 95 18676397 10.1093/bmb/ldn025
4. Bryant SJ. Photocrosslinkable Hydrogels as Cell-scaffolds for Tissue Engineering Cartilage: A Study Examining Gel Properties, Degradation, Mechanical Loading, and Clinical Relevance. Boulder, CO: Chemical Engineering, University of Colorado-Boulder; 2002.
5. SJ Bryant KS Anseth 2002 Hydrogel properties influence ECM production by chondrocytes photoencapsulated in poly(ethylene glycol) hydrogels J Biomed Mater Res. 59 63 72 11745538 10.1002/jbm.1217 1:CAS:528:DC%2BD3MXptVaqu7g%3D (Pubitemid 33131600)
6. SJ Bryant KS Anseth 2003 Controlling the spatial distribution of ECM components in degradable PEG hydrogels for tissue engineering cartilage J Biomed Mater Res A. 64 70 79 12483698 10.1002/jbm.a.10319 (Pubitemid 37521468)
7. SJ Bryant KS Anseth DA Lee DL Bader 2004 Crosslinking density influences the morphology of chondrocytes photoencapsulated in PEG hydrogels during the application of compressive strain J Orthop Res. 22 1143 1149 15304291 10.1016/j.orthres.2004.02.001 1:CAS:528:DC%2BD2cXmsVKhtro%3D (Pubitemid 39145135)
8. SJ Bryant RJ Bender KL Durand KS Anseth 2004 Encapsulating chondrocytes in degrading PEG hydrogels with high modulus: engineering gel structural changes to facilitate cartilaginous tissue production Biotechnol Bioeng. 86 747 755 15162450 10.1002/bit.20160 1:CAS:528:DC%2BD2cXkslCgt70%3D (Pubitemid 38745692)
9. SJ Bryant KL Durand KS Anseth 2003 Manipulations in hydrogel chemistry control photoencapsulated chondrocyte behavior and their extracellular matrix production J Biomed Mater Res A. 67 1430 1436 14624532 10.1002/jbm.a.20003 (Pubitemid 37522759)
10. RW Farndale DJ Buttle AJ Barrett 1986 Improved quantitation and discrimination of sulfated glycosaminoglycans by use of dimethylmethylene blue Biochim Biophys Acta. 883 173 177 3091074 1:CAS:528:DyaL28Xls1yhsrs%3D (Pubitemid 16027978)
11. SD Gillogly M Voight T Blackburn 1998 Treatment of articular cartilage defects of the knee with autologous chondrocyte implantation J Orthop Sports Phys Ther. 28 241 251 9785259 1:STN:280:DyaK1M%2FgtFCgug%3D%3D (Pubitemid 28470980)
12. AJ Grodzinsky ME Levenston M Jin EH Frank 2000 Cartilage tissue remodeling in response to mechanical forces Annu Rev Biomed Eng. 2 691 713 11701528 10.1146/annurev.bioeng.2.1.691 1:CAS:528:DC%2BD3cXnsVakurg%3D
13. AP Hollander TF Heathfield C Webber Y Iwata R Bourne C Rorabeck AR Poole 1994 Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay J Clin Invest. 93 1722 1732 7512992 10.1172/JCI117156 1:CAS:528:DyaK2cXivFGqsrc%3D (Pubitemid 24116414)
14. CT Hung RL Mauck CCB Wang EG Lima GA Ateshian 2004 A paradigm for functional tissue engineering of articular cartilage via applied physiologic deformational loading Ann Biomed Eng. 32 35 49 14964720 10.1023/B:ABME. 0000007789.99565.42
15. CJ Hunter JK Mouw ME Levenston 2004 Dynamic compression of chondrocyte-seeded fibrin gels: effects on matrix accumulation and mechanical stiffness Osteoarthritis Cartilage. 12 117 130 14723871 10.1016/j.joca.2003.08. 009 (Pubitemid 38181119)
16. JD Kisiday MS Jin MA DiMicco B Kurz AJ Grodzinsky 2004 Effects of dynamic compressive loading on chondrocyte biosynthesis in self-assembling peptide scaffolds J Biomech. 37 595 604 15046988 10.1016/j.jbiomech.2003.10.005 (Pubitemid 38445021)
17. JD Kisiday JH Lee PN Siparsky DD Frisbie CR Flannery JD Sandy AJ Grodzinsky 2009 Catabolic responses of chondrocyte-seeded peptide hydrogel to dynamic compression Ann Biomed Eng. 37 1368 1375 19415495 10.1007/s10439-009- 9699-9
18. MM Knight DA Lee DL Bader 1998 The influence of elaborated pericellular matrix on the deformation of isolated articular chondrocytes cultured in agarose Biochim Biophys Acta. 1405 67 77 9784610 10.1016/S0167-4889(98)00102-5 1:CAS:528:DyaK1cXmslOgsLs%3D (Pubitemid 28495628)
19. CR Lee AJ Grodzinsky M Spector 2003 Biosynthetic response of passaged chondrocytes in a type II collagen scaffold to mechanical compression J Biomed Mater Res A. 64 560 569 12579571 10.1002/jbm.a.10443 1:STN:280: DC%2BD3s%2FmvVyjsw%3D%3D (Pubitemid 37522497)
20. DA Lee DL Bader 1997 Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose J Orthop Res. 15 181 188 9167619 10.1002/jor.1100150205 (Pubitemid 27220534)
21. S Lin-Gibson S Bencherif JA Cooper SJ Wetzel JM Antonucci BM Vogel F Horkay NR Washburn 2004 Synthesis and characterization of PEG dimethacrylates and their hydrogels Biomacromolecules. 5 1280 1287 15244441 10.1021/bm0498777 1:CAS:528:DC%2BD2cXjt1aisLw%3D (Pubitemid 39089727)
22. Mark KVD. Structure, biosynthesis, and gene regulation of collagens in cartilage and bones. In: Seibel MJ, Robins SP, Bilezikian JP, eds. Dynamics of Bone and Cartilage Metabolism. Vol 1. 2nd ed. Burlington, VT: Elsevier; 2006:3-40.
23. JA Martin JA Buckwalter 2001 Roles of articular cartilage aging and chondrocyte senescence in the pathogenesis of osteoarthritis Iowa Orthop J. 21 1 7 11813939 1:STN:280:DC%2BD38%2Fos12qtA%3D%3D
24. AC McLaren CP Blokker PJ Fowler JN Roth MG Rock 1991 Arthroscopic débridement of the knee for osteoarthrosis Can J Surg. 34 595 598 1747839 1:STN:280:DyaK38%2FotlCmtg%3D%3D
25. AT Metters KS Anseth CN Bowman 2000 Fundamental studies of a novel, biodegradable PEG-b-PLA hydrogel Polymer. 41 3993 4004 10.1016/S0032-3861(99) 00629-1 1:CAS:528:DC%2BD3cXhslKgsro%3D (Pubitemid 30116901)
26. AT Metters CN Bowman KS Anseth 2000 A statistical kinetic model for the bulk degradation of PLA-b-PEG-b-PLA hydrogel networks J Phys Chem B. 104 7043 7049 10.1021/jp000523t 1:CAS:528:DC%2BD3cXkslWnur0%3D
27. AT Metters CN Bowman KS Anseth 2001 Verification of scaling laws for degrading PLA-b-PEG-b-PLA hydrogels AIChE J. 47 1432 1437 10.1002/aic.690470619 1:CAS:528:DC%2BD3MXksVGgt7k%3D (Pubitemid 36858870)
28. GD Nicodemus SJ Bryant 2008 Cell encapsulation in biodegradable hydrogels for tissue engineering applications Tissue Eng Part B Rev. 14 149 165 18498217 10.1089/ten.teb.2007.0332 1:CAS:528:DC%2BD1cXntFWnu7k%3D (Pubitemid 351839212)
29. GD Nicodemus SJ Bryant 2010 Mechanical loading regimes affect the anabolic and catabolic activities by chondrocytes encapsulated in PEG hydrogels Osteoarthritis Cartilage. 18 126 137 19748607 10.1016/j.joca.2009.08.005 1:STN:280:DC%2BC3c%2FpvFOkug%3D%3D
30. GD Nicodemus KA Shiplet SR Kaltz SJ Bryant 2009 Dynamic compressive loading influences degradation behavior of PEG-PLA hydrogels Biotechnol Bioeng. 102 948 959 18831003 10.1002/bit.22105 1:CAS:528:DC%2BD1MXht1Wmsrk%3D
31. GD Nicodemus I Villanueva SJ Bryant 2007 Mechanical stimulation of TMJ condylar chondrocytes encapsulated in PEG hydrogels J Biomed Mater Res A. 83 323 331 17437304 (Pubitemid 47557381)
32. AG Robling DB Burr CH Turner 2000 Partitioning a daily mechanical stimulus into discrete loading bouts improves the osteogenic response to loading J Bone Miner Res. 15 1596 1602 10934659 10.1359/jbmr.2000.15.8.1596 1:STN:280:DC%2BD3M%2FlsVGksg%3D%3D (Pubitemid 30484530)
33. RL Sah YJ Kim JYH Doong AJ Grodzinsky AH Plaas JD Sandy 1989 Biosynthetic response of cartilage explants to dynamic compression J Orthop Res. 7 619 636 2760736 10.1002/jor.1100070502 1:STN:280:DyaL1MzktF2ruw%3D%3D (Pubitemid 19208087)
34. AS Sawhney CP Pathak JA Hubbell 1993 Bioerodible hydrogels based on photopolymerized poly(ethylene glycol)-co-poly(alpha-hydroxy acid) diacrylate macromers Macromolecules. 26 581 587 10.1021/ma00056a005 1:CAS:528: DyaK3sXhsFChtb4%3D
35. SL Sledge 2001 Microfracture techniques in the treatment of osteochondral injuries Clin Sports Med. 20 365 377 11398363 10.1016/S0278-5919(05)70311-2 1:STN:280:DC%2BD3MzjtVyntA%3D%3D (Pubitemid 32488725)
36. JR Steadman WG Rodkey KK Briggs JJ Rodrigo 1999 The microfracture technic in the management of complete cartilage defects in the knee joint [in German] Orthopade. 28 26 32 10081041 1:STN:280:DyaK1M7otVyrsA%3D%3D (Pubitemid 29142911)
37. I Villanueva DS Hauschulz D Mejic SJ Bryant 2008 Static and dynamic compressive strains influence nitric oxide production and chondrocyte bioactivity when encapsulated in PEG hydrogels of different crosslinking densities Osteoarthritis Cartilage. 16 909 918 18203631 10.1016/j.joca.2007.12. 003 1:STN:280:DC%2BD1cvksV2qtQ%3D%3D
38. SD Waldman DC Couto MD Grynpas RM Pilliar RA Kandel 2006 A single application of cyclic loading can accelerate matrix deposition and enhance the properties of tissue-engineered cartilage Osteoarthritis Cartilage. 14 323 330 16324852 10.1016/j.joca.2005.10.007 1:STN:280:DC%2BD28zkslyhug%3D%3D
39. JF Woessner 1961 Determination of hydroxyproline in tissue and protein samples containing small proportions of this amino acid Arch Biochem Biophys. 93 440 447 13786180 10.1016/0003-9861(61)90291-0 1:CAS:528:DyaF3MXht1Ghu7c%3D