Expression and prognostic value of VEGF-C and lymphangeogenesis in lung adenocarcinoma and squamous cell carcinoma

Chinese Journal of Lung Cancer

Volumn 14, Issue 10, 2011, Pages 774-779

  Dai, Xueli ^a   Wang, Wenli ^a   Shen Tu, Yang ^a   Zhang, Jie ^a  

^a SHANGHAI CHEST HOSPITAL   (China)

Author keywords

Lung neoplasms; Lymphangiogenesis; Prognosis; Vascular endothelial growth factor c

Indexed keywords

VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 3;

ARTICLE; CANCER STAGING; ENDOTHELIUM CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; LUNG ADENOCARCINOMA; LUNG ALVEOLUS CELL; LUNG CARCINOMA; LUNG SQUAMOUS CELL CARCINOMA; LYMPH NODE METASTASIS; LYMPH VESSEL; LYMPHANGIOGENESIS; MAJOR CLINICAL STUDY; PROGNOSIS; SURVIVAL RATE;

ADENOCARCINOMA; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; LYMPHANGIOGENESIS; LYMPHATIC VESSELS; MALE; MICROVESSELS; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PROGNOSIS; VASCULAR ENDOTHELIAL GROWTH FACTOR C;

EID: 80054753182     PISSN: 10093419     EISSN: 19996187     Source Type: Journal    
DOI: 10.3779/j.issn.1009-3419.2011.10.02     Document Type: Article

References (15)

1. Nakashima T, Huang CL, Liu D, et al. Expression of vascular endothelial growth factor-A and vascular endothelial growth factor-C as prognostic factors for non-small cell lung cancer. Med Sci Monit, 2004, 10(6): BR157-65.
2. Saintigny P, Kambouchner M, Ly M, et al. Vascular endothelial growth factor-C and its receptor VEGFR-3 in non-small-cell lung cancer: concurrent expression in cancer cells from primary tumour and metastatic lymph node. Lung Cancer, 2007, 58(2): 205-213.
3. Takizawa H, Kondo K, Fujino H, et al. The balance of VEGF-C and VEGFR- 3 mRNA is a predictor of lymph node metastasis in non-small cell lung cancer. Br J Cancer, 2006, 95(1): 75-79.
4. Pepper MS. Lymphangiogenesis and tumor metastasis more questions than answers. Lymphology, 2000, 33(4): 144-147.
5. Pisters KMW, Le Chevalier T. Adjuvant chemotherapy incompletely resected non-small cell lung cancer. J Clin Oncol, 2005, 23(14): 3270-3278.
6. Broughton HB. A method for including protein flexibility in protein-ligand docking: improving tools for database mining and virtual screening. J Mol Graph Model, 2000, 18(3): 247-257, 302-304.
7. Kriehuber E, Breiteneder-Geleff S, Groeger M, et al. Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages. J Exp Med, 2001, 194(6): 797-808.
8. Eichmann A, Corbel C, Jaffredo T, et al. Avian VEGF-C: cloning, embryonic expression-pattern and stimulation of the diferentiation of VEGFB2-expressing endothelial cell precursors. Development, 1998, 125(4): 743-752.
9. Ohta Y, Nozawa H, Tanaka Y, et al. Increased vascular endothelial growth factor-c and decreased nm23 expression associated with microdissemination in the lymph nodes in stage I non-small cell lung cancer. J Thorac Cardiovasc Surg, 2000, 119(4 Pt 1): 804-813.
10. Dong X, Qiu XS, Wang EH, et al. Expression of vascular endothelial growth factor-C and VEGF receptor-3 in non-smal cell lung cancer. Chin J Pathol, 2003, 32(2): 128-132.
11. Faoro L, Hutto JY, Salgia R, et al. Lymphatic vessel density is not associated with lymph node metastasis in non-small cell lung carcinoma. Arch Pathol Lab Med, 2008, 132(12): 1882-1888.
12. Kajita T, Ohta Y, Kimura K, et al. The expression of vascular endothelial growth factor C and its receptors in non-small cell lung cancer. Br J Cancer, 2001, 85(2): 255-260.
13. Li Q, Dong X, Gu W, et al. Clinical significance of co-expression of VEGF-C and VEGFR-3 in non-small cell lung cancer. Chin Med J (Engl), 2003, 116(5): 727-730.
14. Arinaga M, Noguchi T, Takeno S, et al. Clinical significance of vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 in patients with nonsmall cell lung carcinoma. Cancer, 2003, 97(2): 457-464.
15. Ogawa E, Takenaka K, Yanagihara K, et al. Clinical significance of VEGF-C status in tumour cells and stromal macrophages in non-small cell lung cancer patients. Br J Cancer, 2004, 91(3): 498-503.