Cytotoxicity assays of new artificial tears containing 2- methacryloyloxyethyl phosphorylcholine polymer for ocular surface cells

Japanese Journal of Ophthalmology

Volumn 55, Issue 5, 2011, Pages 541-546

  Ayaki, Masahiko ^a   Iwasawa, Atsuo ^b   Niwano, Yoshimi ^c  

^a SAITAMA NATIONAL HOSPITAL   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

Biomaterials; Cornea; Cytotoxicity; Dry eye; Phospholipid polymer

Indexed keywords

2 METHACRYLOYLOXYETHYLPHOSPHORYLCHOLINE; ARTIFICIAL TEAR; BENZALKONIUM CHLORIDE; BORIC ACID; CHLORHEXIDINE; EYE DROPS; HYALEIN MINI; HYALURONIC ACID; METHACRYLIC ACID BUTYL ESTER; METHACRYLIC ACID DERIVATIVE; POLY(HEXAMETHYLENEBIGUANIDE); TEAR BALANCE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONJUNCTIVA; CONTROLLED STUDY; CORNEA CELL; DILUTION; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CATTLE; CELL LINE; CELL SURVIVAL; CONJUNCTIVA; CORNEA; EPITHELIAL CELLS; HUMANS; METHACRYLATES; OPHTHALMIC SOLUTIONS; PHOSPHORYLCHOLINE; RABBITS; TOXICITY TESTS;

EID: 80054749695     PISSN: 00215155     EISSN: 16132246     Source Type: Journal    
DOI: 10.1007/s10384-011-0073-8     Document Type: Article

References (44)

1. Epidemiology Subcommittee of the International Dry Eye WorkShop. The epidemiology of dry eye disease: report of the Epidemiology Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf. 2007;5:93-107.
2. Epidemiology Subcommittee of the International Dry Eye WorkShop. The definition and classification of dry eye disease: report of the Epidemiology Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf. 2007;5:75-92.
3. P Furrer JM Mayer R Gurny 2002 Ocular tolerance of preservatives and alternatives Eur J Pharm Biopharm 53 263 280 11976014 10.1016/S0939-6411(01) 00246-6 1:CAS:528:DC%2BD38XjtVeisbY%3D (Pubitemid 34303289)
4. C Baudoiun A Labbé H Liang A Pauly F Brignole-Baudouin 2010 Preservatives in eyedrops: the good, the bad and the ugly Prog Retin Eye Res 29 312 334 10.1016/j.preteyeres.2010.03.001
5. K Tsubota 1998 Tear dynamics and dry eye Prog Retin Eye Res 17 565 596 9777650 10.1016/S1350-9462(98)00004-4 1:STN:280:DyaK1cvltVyhtw%3D%3D (Pubitemid 28432981)
6. NL Burnstein 1985 The effect of topical drugs and preservatives on the tears and corneal epithelium in dry eye Trans Ophthalmol Soc UK 104 402 409
7. S Khanal A Tomlinson A McFadyen C Diaper K Ramaesh 2008 Dry eye diagnosis Inv Ophthalmol Vis Sci 49 1407 1414 10.1167/iovs.07-0635
8. K Ishihara R Aragaki T Ueda A Watenabe N Nakabayashi 1990 Reduced thrombogenicity of polymers having phospholipid polar groups J Biomed Mater Res 24 1069 1077 2394763 10.1002/jbm.820240809 1:CAS:528:DyaK3MXovVGrsQ%3D%3D (Pubitemid 20279660)
9. Ishihara K, Takai M. Bioinspired interface for nanobiodevices based on phospholipid polymer chemistry. J R Soc Interface. 2009;6 Suppl 3:S279-91.
10. K Ishihara 2000 Bioinspired phospholipid polymer biomaterials for making high performance artificial organs Sci Technol Adv Mater 1 131 138 10.1016/S1468-6996(00)00012-7 1:CAS:528:DC%2BD3MXmslyqtrw%3D
11. Ishihara K. New polymeric biomaterials-phospholipid polymers with a biocompatible surface. Front Med Biol Eng. 2000;10:83-95.
12. Y Iwasaki S Sawada N Nakabayashi G Khang HB Lee 1999 Ishihara K. The effect of the chemical structure of the phospholipid polymer on fibronectin adsorption and fibroblast adhesion on the gradient phospholipid surface Biomaterials 20 2185 2191 10555087 10.1016/S0142-9612(99)00123-4 1:CAS:528:DyaK1MXntFClsb8%3D (Pubitemid 29488668)
13. K Ishihara E Ishikawa Y Iwasaki N Nakabayashi 1999 Inhibition of fibroblast cell adhesion on substrate by coating 2-methacryloyloxyethyl phosphorylcholine polymers J Biomater Sci Polymer Ed 10 1047 1061 10.1163/156856299X00676 1:CAS:528:DyaK1MXnvVCrs78%3D
14. SH Ye J Watanabe Y Iwasaki K Ishihara 2003 Antifouling blood purification membrane composed of cellulose acetate and phospholipid polymer Biomaterials 24 4143 4152 12853244 10.1016/S0142-9612(03)00296-5 1:CAS:528:DC%2BD3sXltFClt74%3D (Pubitemid 36809016)
15. S Sawada S Sakaki Y Iwasaki N Nakabayashi 2003 Ishihara K. Suppression of the inflammatory response from adherent cells on phospholipid polymers J Biomed Mater Res A 64 411 416 12579554 10.1002/jbm.a.10433 (Pubitemid 37522480)
16. Y Iwasaki S Sawada K Ishihara G Khang HB Lee 2002 Reduction of surface-induced inflammatory reaction on PLGA/MPC polymer blend Biomaterials 23 3897 3903 12164195 10.1016/S0142-9612(02)00135-7 1:CAS:528:DC%2BD38Xls1Whur0%3D (Pubitemid 34828163)
17. T Goda R Matsuno T Konno M Takai K Ishihara 2009 Protein adsorption resistance and oxygen permeability of chemically crosslinked phospholipid polymer hydrogel for ophthalmologic biomaterials J Biomed Mater Res B Appl Biomater 89 184 190 18777582
18. T Goda K Ishihara 2006 Soft contact lens biomaterials from bioinspired phospholipid polymers Expert Rev Med Devices 3 167 174 16515383 10.1586/17434440.3.2.167 1:CAS:528:DC%2BD28Xjt12nt7g%3D
19. Y Okajima S Saika M Sawa 2006 Effect of surface coating an acrylic intraocular lens with poly(2-methacryloyloxyethyl phosphorylcholine) polymer on lens epithelial cell line behavior J Cataract Refract Surg 32 666 671 16698492 10.1016/j.jcrs.2006.01.039 (Pubitemid 43673848)
20. W Liu C Deng CR McLaughlin P Fagerholm NS Lagali B Heyne, et al. 2009 Collagen-phosphorylcholine interpenetrating network hydrogels as corneal substitutes Biomaterials 30 1551 1559 19097643 10.1016/j.biomaterials.2008.11. 022 1:CAS:528:DC%2BD1MXpsFyjsw%3D%3D
21. FM Polack MT McNiece 1982 The treatment of dry eye with Na hyaluronate (Healon) Cornea 1 133 136
22. N Yokoi A Komuro K Nishida S Kinoshita 1997 Effectiveness of hyaluronan on corneal epithelial barrier function in dry eye Br J Ophthalmol 81 533 536 9290362 10.1136/bjo.81.7.533 1:STN:280:DyaK2svjsFKqtw%3D%3D (Pubitemid 27354923)
23. M Nakamura N Sato TI Chikama Y Hasegawa T Nishida 1997 Hyaluronan facilitates corneal epithelial wound healing in diabetic rats Exp Eye Res 64 1043 1050 9301486 10.1006/exer.1997.0302 1:CAS:528:DyaK2sXks1aqu7g%3D (Pubitemid 27314780)
24. ME Johnson PJ Murphy M Boulton 2006 Effectiveness of sodium hyaluronate eyedrops in the treatment of dry eye Graefes Arch Clin Exp Ophthalmol 244 109 112 15983814 10.1007/s00417-005-0028-1 1:CAS:528:DC%2BD2MXht1KnsLnE (Pubitemid 43013190)
25. P Troiano G Monaco 2008 Effect of hypotonic 0.4% SH drops in dry eye patients: a cross-over study Cornea 27 1126 1130 19034126 10.1097/ICO. 0b013e318180e55c
26. C Debbasch SB De La Salle F Brignole P Rat JM Warnet C Baudouin 2002 Cytoprotective effects of SH and Carbomer 934P in ocular surface epithelial cells Invest Ophthalmol Vis Sci 43 3409 3415 12407150 (Pubitemid 35334347)
27. NL Burstein SD Klyce 1977 Electrophysiologic and morphologic effects of ophthalmic preparations on rabbit cornea epithelium Invest Ophthalmol Vis Sci 16 899 911 908644 1:CAS:528:DyaE1cXhsFyitQ%3D%3D (Pubitemid 8201831)
28. M De Saint Jean F Brignole AF Bringuier A Bauchet G Feldmann C Baudouin 1999 Effects of benzalkonium chloride on growth and viability of Chang conjunctival cells Invest Ophthalmol Vis Sci 40 619 630 10067965 (Pubitemid 29109440)
29. RR Pfister NL Burstein 1976 The effects of ophthalmic drugs, vehicles, and preservatives on corneal epithelium: a scanning electron microscope study Invest Ophthalmol Vis Sci 15 246 259 1:STN:280:DyaE287ms12qtA%3D%3D
30. AR Gasset Y Ishii 1975 Cytotoxicity of chlorhexidine Can J Ophthalmol 10 98 100 1168090 1:STN:280:DyaE2M7ivFSjtA%3D%3D
31. G Müller A Kramer 2008 Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity J Antimicrob Chemother 61 1281 1287 18364400 10.1093/jac/dkn125 (Pubitemid 351753595)
32. Larkin DF, Kilvington S, Dart JK. Treatment of Acanthamoeba keratitis with polyhexamethylene biguanide. Ophthalmology. 1992;99:185-91.
33. G Young N Keir C Hunt CA Woods 2009 Clinical evaluation of long-term users of two contact lens care preservative systems Eye 35 50 58
34. SA Hubbard 1998 Comparative toxicology of borates Biol Trace Elem Res 66 343 357 10050929 10.1007/BF02783147 1:CAS:528:DyaK1MXht1Citbs%3D (Pubitemid 29093992)
35. G van Rij WH Beekhuis CA Eggink AJ Geerards L Remeijer EL Pels 1995 Toxic keratopathy due to the accidental use of chlorhexidine, cetrimide and cialit Doc Ophthalmol 90 7 14 8549246 10.1007/BF01203289
36. N Anders J Wollensak 1997 Inadvertent use of chlorhexidine instead of balanced salt solution for intraocular irrigation J Cataract Refract Surg 23 959 962 9292687 1:STN:280:DyaK2svjs1Oitg%3D%3D (Pubitemid 27375317)
37. H Liu I Routley KD Teichmann 2001 Toxic endothelial cell destruction from intraocular benzalkonium chloride J Cataract Refract Surg 27 1746 1750 11709246 10.1016/S0886-3350(01)01067-7 1:STN:280:DC%2BD3MnmtlOksA%3D%3D (Pubitemid 33055543)
38. T Mosmann 1983 Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J Immunol Methods 65 55 63 6606682 10.1016/0022-1759(83)90303-4 1:STN:280:DyaL2c%2FovFSmtw%3D%3D (Pubitemid 14203433)
39. F Denizot R Lang 1986 Rapid colorimetric assay for cell growth and viability: modifications to the tetrazolium dye procedure giving improved sensitivity and reliability J Immunol Methods 89 271 277 3486233 10.1016/0022-1759(86)90368-6 1:STN:280:DyaL287psl2jsA%3D%3D (Pubitemid 16080782)
40. E Borenfreund JA Puerner 1985 Toxicity determined in vitro by morphological alterations and neutral red absorption Toxicol Lett 24 119 124 3983963 10.1016/0378-4274(85)90046-3 1:CAS:528:DyaL2MXhvVShu7s%3D (Pubitemid 15103513)
41. M Ayaki A Iwasawa S Yaguchi R Koide 2010 Preserved and unpreserved 12 anti-allergic ophthalmic solutions and ocular surface toxicity: in vitro assessment in four cultured corneal and conjunctival epithelial cell lines Biocontrol Sci 15 143 148 21212507 10.4265/bio.15.143 1:CAS:528: DC%2BC3MXpsVyqtA%3D%3D
42. M Ayaki A Iwasawa Y Inoue 2010 Toxicity of antiglaucoma drugs with and without benzalkonium chloride to cultured human corneal endothelial cells Clin Ophthalmology 4 1217 1222 10.2147/OPTH.S13708 1:CAS:528:DC%2BC3MXit1CnsL8%3D
43. K Kawazu K Yamada M Nakamura A Ota 1999 Characterization of cyclosporin A transport in cultured rabbit corneal epithelial cells: P-glycoprotein transport activity and binding to cyclophilin Invest Ophthalmol Vis Sci 40 1738 1744 10393043 1:STN:280:DyaK1MzitVaitg%3D%3D (Pubitemid 29297149)
44. CD Xiang M Batugo DC Gale T Zhang J Ye C Li, et al. 2009 Characterization of human corneal epithelial cell model as a surrogate for corneal permeability assessment: metabolism and transport Drug Metab Dispos 37 992 998 19220984 10.1124/dmd.108.026286 1:CAS:528:DC%2BD1MXlsVWitLc%3D