Preoperative staging of cervical cancer: Is 18-FDG-PET/CT really effective in patients with early stage disease?

Gynecologic Oncology

Volumn 123, Issue 2, 2011, Pages 236-240

  Signorelli, Mauro ^a   Guerra, Luca ^a   Montanelli, Luca ^a   Crivellaro, Cinzia ^a   Buda, Alessandro ^a   Dell'Anna, Tiziana ^a   Picchio, Maria ^b   Milani, Rodolfo ^a   Fruscio, Robert ^a   Messa, Cristina ^a  

^a SAN GERARDO HOSPITAL   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

18F fluorodeoxyglucose Positron Emission Tomography Computed Tomography; Cervical cancer; Early stage

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ARTICLE; CANCER PATIENT; CANCER STAGING; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CYSTOSCOPY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DRUG UPTAKE; EARLY CANCER; FEMALE; HISTOPATHOLOGY; HUMAN; IMAGE ANALYSIS; LYMPH NODE METASTASIS; LYMPHADENECTOMY; MAJOR CLINICAL STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; PELVIS LYMPH NODE; POSITRON EMISSION TOMOGRAPHY; PREDICTIVE VALUE; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RADICAL HYSTERECTOMY; SENSITIVITY AND SPECIFICITY; THORAX RADIOGRAPHY; TREATMENT PLANNING; TUMOR VOLUME; UROGRAPHY; UTERINE CERVIX CARCINOMA;

ADULT; AGED; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; MIDDLE AGED; NEOPLASM STAGING; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; PROSPECTIVE STUDIES; RADIOPHARMACEUTICALS; UTERINE CERVICAL NEOPLASMS;

EID: 80054743247     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2011.07.096     Document Type: Article

References (50)

1. D.M. Parkin, F. Bray, J. Ferlay, and P. Pisani Global cancer statistics, 2002 CA Cancer J Clin 55 2005 74 108
2. F. Landoni, A. Maneo, A. Colombo, F. Placa, R. Milani, and P. Perego Randomised study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer Lancet 350 9077 Aug 23 1997 535 540
3. S. Pecorelli, L. Zigliani, and F. Odicino Revised FIGO staging for carcinoma of the cervix Int J Gynaecol Obstet 105 2 May 2009 107 108
4. A. Sedlis, B.N. Bundy, M.Z. Rotman, S.S. Lentz, L.I. Muderspach, and R.J. Zaino A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage IB carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy: a gynecologic oncology group study Gynecol Oncol 73 2 May 1999 177 183
5. C.H. Lai, J.H. Hong, S. Hsueh, K.K. Ng, T.C. Chang, and C.J. Tseng Preoperative prognostic variables and the impact of postoperative adjuvant therapy on the outcomes of stage IB or II cervical carcinoma patients with or without pelvic lymph node metastases: an analysis of 891 cases Cancer 85 1999 1537 1546
6. F. Girardi, and J. Haas The importance of the histologic processing of pelvic lymph nodes in the treatment of cervical cancer Int J Gynecol Cancer 3 1993 12 17
7. Y. Tanaka, S. Sawada, and T. Murata Relationship between lymph node metastases and prognosis in patients irradiated postoperatively for carcinoma of the uterine cervix Acta Radiol Oncol 23 1984 455 459
8. S.E. Waggoner Cervical cancer Lancet 361 2003 2217 2225
9. P.W. Grigsby Role of PET in gynecologic malignancy Curr Opin Oncol 5 Sep 21 2009 420 424 Review
10. P.W. Grigsby, B.A. Siegel, and F. Dehdashti Lymph node staging by positron emission tomography in patients with carcinoma of the cervix J Clin Oncol 19 2001 3745 3749
11. S. Sironi, A. Buda, M. Picchio, P. Perego, R. Moreni, and A. Pellegrino Lymph node metastasis in patients with clinical early-stage cervical cancer: detection with integrated FDG PET/CT Radiology 238 1 Jan 2006 272 279
12. M. Signorelli, L. Guerra, A. Buda, M. Picchio, G. Mangili, and T. Dell'Anna Role of the integrated FDG PET/CT in the surgical management of patients with high risk clinical early stage endometrial cancer: detection of pelvic nodal metastases Gynecol Oncol 115 2 Nov 2009 231 235
13. H.H. Chung, H. Jo, W.J. Kang, J.W. Kim, N.H. Park, and Y.S. Song Clinical impact of integrated PET/CT on the management of suspected cervical cancer recurrence Gynecol Oncol 104 3 Mar 2007 529 534
14. M.J. Reinhardt, C. Ehritt-Braun, D. Vogelgesang, C. Ihling, S. Högerle, and M. Mix Metastatic lymph nodes in patients with cervical cancer: detection with MR imaging and FDG PET Radiology 218 3 Mar 2001 776 782
15. Y. Yildirim, S. Sehirali, M.E. Avci, C. Yilmaz, K. Ertopcu, and S. Tinar Integrated PET/CT for the evaluation of para-aortic nodal metastasis in locally advanced cervical cancer patients with negative conventional CT findings Gynecol Oncol 108 1 Jan 2008 154 159
16. E. Leblanc, H. Gauthier, D. Querleu, G. Ferron, S. Zerdoud, and P. Morice Accuracy of 18-Fluoro-2-deoxy-D: -glucose Positron Emission Tomography in the Pretherapeutic Detection of Occult Para-aortic Node Involvement in Patients with a Locally Advanced Cervical Carcinoma Ann Surg Oncol. 18 8 Aug 2011 2302 2309 Epub 2011 Feb 23
17. W.C. Lin, Y.C. Hung, L.S. Yeh, C.H. Kao, R.F. Yen, and Y.Y. Shen Usefulness of (18)F-fluorodeoxyglucose positron emission tomography to detect para-aortic lymph nodal metastasis in advanced cervical cancer with negative computed tomography findings Gynecol Oncol 89 1 Apr 2003 73 76
18. F. Landoni, A. Maneo, G. Cormio, P. Perego, R. Milani, and O. Caruso Class II versus class III radical hysterectomy in stage IB-IIA cervical cancer: a prospective randomized study Gynecol Oncol 80 1 Jan 2001 3 12
19. Chemoradiotherapy for Cervical Cancer Meta-Analysis Collaboration Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer: a systematic review and meta-analysis of individual patient data from 18 randomized trials J Clin Oncol 26 2008 5802 5812
20. Neoadjuvant Chemotherapy for Locally Advanced Cervical Cancer Meta-analysis Collaboration Neoadjuvant chemotherapy for locally advanced cervical cancer: a systematic review and meta-analysis of individual patient data from 21 randomised trials Eur J Cancer 39 17 Nov 2003 2470 2486 Review
21. E. Burghardt, H. Pickel, J. Haas, and M. Lahousen Prognostic factors and operative treatment of stages IB to IIB cervical cancer Am J Obstet Gynecol 156 4 Apr 1987 988 996
22. D.G. Mitchell, B. Snyder, F. Coakley, C. Reinhold, G. Thomas, and M. Amendola Early invasive cervical cancer: tumor delineation by magnetic resonance imaging, computed tomography, and clinical examination, verified by pathologic results, in the ACRIN 6651/GOG 183 Intergroup Study J Clin Oncol 24 36 2006 5687 5694
23. J.R. Van Nagell Jr. , J.W. Roddick Jr. , and D.M. Lowin The staging of cervical cancer: inevitable discrepancies between clinical staging and pathologic findings Am J Obstet Gynecol 110 1971 973 978
24. H. Noguchi, I. Shiozawa, Y. Sakai, T. Yamazaki, and T. Fukuta Pelvic lymph node metastasis of uterine cervical cancer Gynecol Oncol 27 1987 150 158
25. N. Sakuragi, C. Satoh, N. Takeda, H. Hareyama, M. Takeda, and R. Yamamoto Incidence and distribution pattern of pelvic and paraaortic lymph node metastasis in patients with stages IB, IIA, and IIB cervical carcinoma treated with radical hysterectomy Cancer 85 1999 1547 1554
26. P. Benedetti-Panici, F. Maneschi, G. Scambia, S. Greggi, G. Cutillo, and G. D'Andrea Lymphatic spread of cervical cancer: an anatomical and pathological study based on 225 radical hysterectomies with systematic pelvic and aortic lymphadenectomy Gynecol Oncol 62 1 Jul 1996 19 24
27. National Institutes of Health Consensus Development Conference Statement: cervical cancer, April 1-3, 1996 National Institutes of Health Consensus Development Panel J Natl Cancer Inst Monogr 21 1996 1 38 Review
28. H.J. Choi, J.W. Roh, S.S. Seo, S. Lee, J.Y. Kim, and S.K. Kim Comparison of the accuracy of magnetic resonance imaging and positron emission tomography/computed tomography in the presurgical detection of lymph node metastases in patients with uterine cervical carcinoma: a prospective study Cancer 106 2006 914 922
29. J. Scheidler, H. Hricak, K.K. Yu, L. Subak, and M.R. Segal Radiological evaluation of lymph node metastases in patients with cervical cancer: a meta-analysis JAMA 278 1997 1096 1101
30. J.M. Hawnaur, R.J. Johnson, C.H. Buckley, V. Tindall, and I. Isherwood Staging, volume estimation and assessment of nodal status in carcinoma of the cervix: comparison of magnetic resonance imaging with surgical findings Clin Radiol 49 7 Jul 1994 443 452
31. K. Matsukuma, N. Tsukamoto, T. Matsuyama, M. Ono, and H. Nakano Preoperative CT study of lymph nodes in cervical cancer: its correlation with histological findings Gynecol Oncol 33 1989 168 171
32. S.H. Kim, B.I. Choi, H.P. Lee, S.B. Kang, Y.M. Choi, and M.C. Han Uterine cervical carcinoma: comparison of CT and MR findings Radiology 175 1990 45 51
33. S.H. Kim, S.C. Kim, B.I. Choi, and M.C. Han Uterine cervical carcinoma: evaluation of pelvic lymph node metastasis with MR imaging Radiology 190 1994 807 811
34. H. Hricak, C.B. Powell, K.K. Yu, E. Washington, L.L. Subak, and J.L. Stern Invasive cervical carcinoma: role of MR imaging in pretreatment work-up-cost minimization and diagnostic efficacy analysis Radiology. 198 2 Feb 1996 403 409
35. W.T. Yang, W.M. Lam, M.Y. Yu, T.H. Cheung, and C. Metreweli Comparison of dynamic helical CT and dynamic MR imaging in the evaluation of pelvic lymph nodes in cervical carcinoma AJR Am J Roentgenol 175 2000 759 766
36. I. Ak, M.P. Stokkel, and E.K. Pauwels Positron emission tomography with 2-[18F]fluoro-2-deoxy-D glucose in oncology. Part II. The clinical value in detecting and staging primary tumours J Cancer Res Clin Oncol 126 10 2000 560 574
37. T.F. Cermik, A. Mavi, S. Basu, and A. Alavi Impact of FDG PET on the preoperative staging of newly diagnosed breast cancer Eur J Nucl Med Mol Imaging 35 3 (Mar)2008 475 483
38. E.M. Rohren, T.G. Turkington, and R.E. Coleman Clinical applications of PET in oncology Radiology 231 2004 305 332
39. T.F. Hany, H.C. Steinert, G.W. Goerres, A. Buck, and G.K. von Schulthess PET diagnostic accuracy: improvement with in-line PET/CT system-initial results Radiology 225 2002 575 581
40. H.H. Chou, T.C. Chang, T.C. Yen, K.K. Ng, S. Hsueh, and S.Y. Ma Low value of [18F]-fluoro-2-deoxy-D-glucose positron emission tomography in primary staging of early-stage cervical cancer before radical hysterectomy J Clin Oncol 24 2006 123 128
41. T. Belhocine, A. Thille, V. Fridman, A. Albert, L. Seidel, and P. Nickers Contribution of whole-body 18FDG PET imaging in the management of cervical cancer Gynecol Oncol 87 1 Oct 2002 90 97
42. A.D. Williams, C. Cousins, W.P. Soutter, M. Mubashar, A.M. Peters, and R. Dina Detection of pelvic lymph node metastases in gynecologic malignancy: a comparison of CT, MR imaging, and positron emission tomography AJR Am J Roentgenol 177 2001 343 348
43. H.H. Chung, K.W. Kang, J.Y. Cho, J.W. Kim, N.H. Park, and Y.S. Song Role of magnetic resonance imaging and positron emission tomography/computed tomography in preoperative lymph node detection of uterine cervical cancer Am J Obstet Gynecol 203 2 Aug 2010 156.e1 156.e5
44. P.T. Ramirez, A. Jhingran, H.A. Macapinlac, E.D. Euscher, M.F. Munsell, and R.L. Coleman Laparoscopic extraperitoneal para-aortic lymphadenectomy in locally advanced cervical cancer: a prospective correlation of surgical findings with positron emission tomography/computed tomography findings Cancer 117 9 May 1 2011 1928 1934
45. J.D. Wright, F. Dehdashti, T.J. Herzog, D.G. Mutch, P.C. Huettner, and J.S. Rader Preoperative lymph node staging of early-stage cervical carcinoma by [18F]-fluoro-2-deoxy-D-glucose-positron emission tomography Cancer 104 11 Dec 1 2005 2484 2491
46. W. Park, Y.J. Park, S.J. Huh, B.G. Kim, D.S. Bae, and J. Lee The usefulness of MRI and PET imaging for the detection of parametrial involvement and lymph node metastasis in patients with cervical cancer Jpn J Clin Oncol 35 5 May 2005 260 264
47. L. Yu, C. Jia, X. Wang, P. Lu, M. Tian, and W. Wang Evaluation of 18F-FDG PET/CT in early-stage cervical carcinoma Am J Med Sci 341 2 Feb 2011 96 100
48. A. Amit, D. Beck, L. Lowenstein, O. Lavie, R. Bar Shalom, and Z. Kedar The role of hybrid PET/CT in the evaluation of patients with cervical cancer Gynecol Oncol 100 1 Jan 2006 65 69
49. A. Loft, A.K. Berthelsen, H. Roed, C. Ottosen, L. Lundvall, and J. Knudsen The diagnostic value of PET/CT scanning in patients with cervical cancer: a prospective study Gynecol Oncol 106 1 Jul 2007 29 34
50. B.K. Goyal, H. Singh, K. Kapur, B.S. Duggal, and M.J. Jacob Value of PET-CT in avoiding multimodality therapy in operable cervical cancer Int J Gynecol Cancer 20 6 Aug 2010 1041 1045