Rab22 controls NGF signaling and neurite outgrowth in PC12 cells

Molecular Biology of the Cell

Volumn 22, Issue 20, 2011, Pages 3853-3860

  Wang, Liang ^a   Liang, Zhimin ^a   Li, Guangpu ^a,b  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b FUJIAN AGRICULTURE AND FORESTRY UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE GROWTH FACTOR; PROTEIN RAB22; PROTEIN RABEX 5; PROTEIN TYROSINE KINASE A; RAB PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; GENE EXPRESSION; GENE OVEREXPRESSION; INTRACELLULAR SIGNALING; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; REGULATORY MECHANISM;

ANIMALS; CELL COMMUNICATION; CELL DIFFERENTIATION; ENDOCYTOSIS; ENDOSOMES; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MICROSCOPY, FLUORESCENCE; NERVE GROWTH FACTOR; NEURITES; NEUROGENESIS; PC12 CELLS; PHOSPHORYLATION; PROTEIN BINDING; RAB GTP-BINDING PROTEINS; RATS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, TRKA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 80054713625     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E11-03-0277     Document Type: Article

References (31)

1. Bucci C, Parton RG, Mather IH, Stunnenberg H, Simons K, Hoflack B, Zerial M (1992). The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway. Cell 70, 715-728.
2. Delcroix JD, Valletta JS, Wu C, Hunt SJ, Kowal AS, Mobley WC (2003). NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signals. Neuron 39, 69-84. (Pubitemid 36830949)
3. Delprato A, Merithew E, Lambright DG (2004). Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5. Cell 118, 607-617. (Pubitemid 39179713)
4. de Renzis S, Sonnichsen B, Zerial M (2002). Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes. Nat Cell Biol 4, 124-133. (Pubitemid 34141478)
5. Greene LA, Tischler AS (1976). Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA 73, 2424-2428.
6. Horiuchi H et al. (1997). A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function. Cell 90, 1149-1159. (Pubitemid 27408528)
7. Huang EJ, Reichardt LF (2003). Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem 72, 609-642. (Pubitemid 36930455)
8. Kalesnikoff J, Rios EJ, Chen CC, Alejandro Barbieri M, Tsai M, Tam SY, Galli SJ (2007). Roles of RabGEF1/Rabex-5 domains in regulating FcεRI surface expression and FcεRI-dependent responses in mast cells. Blood 109, 5308-5317. (Pubitemid 46890552)
9. Kauppi M, Simonsen A, Bremnes B, Vieira A, Callaghan J, Stenmark H, Olkkonen VM (2002). The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking. J Cell Sci 115, 899-911. (Pubitemid 34257375)
10. Kuruvilla R, Zweifel LS, Glebova NO, Lonze BE, Valdez G, Ye H, Ginty DD (2004). A neurotrophin signaling cascade coordinates sympathetic neuron development through differential control of TrkA trafficking and retrograde signaling. Cell 118, 243-255. (Pubitemid 38962579)
11. Levi A, Eldridge JD, Paterson BM (1985). Molecular cloning of a gene sequence regulated by nerve growth factor. Science 229, 393-395. (Pubitemid 15073084)
12. Li G, Barbieri MA, Colombo MI, Stahl PD (1994). Structural features of the GTP-binding defective Rab5 mutants required for their inhibitory activity on endocytosis. J Biol Chem 269, 14631-14635. (Pubitemid 24194024)
13. Liu J, Lamb D, Chou MM, Liu YJ, Li G (2007). Nerve growth factor-mediated neurite outgrowth via regulation of Rab5. Mol Biol Cell 18, 1375-1384. (Pubitemid 46626632)
14. Magadan JG, Barbieri MA, Mesa R, Stahl PD, Mayorga LS (2006). Rab22a regulates the sorting of transferrin to recycling endosomes. Mol Cell Biol 26, 2595-2614.
15. Miaczynska M, Christoforidis S, Giner A, Shevchenko A, Uttenweiler-Joseph S, Habermann B, Wilm M, Parton RG, Zerial M (2004). APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment. Cell 116, 445-456. (Pubitemid 38366320)
16. Mishra A, Eathiraj S, Corvera S, Lambright DG (2010). Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1). Proc Natl Acad Sci USA 107, 10866-10871.
17. Nordmann M, Cabrera M, Perz A, Brocker C, Ostrowicz C, Engelbrecht-Vandre S, Ungermann C (2010). The Mon1-Ccz1 complex is the GEF of the late endosomal Rab7 homolog Ypt7. Curr Biol 20, 1654-1659.
18. Ohya T, Miaczynska M, Coskun U, Lommer B, Runge A, Drechsel D, Kalaidzidis Y, Zerial M (2009). Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes. Nature 459, 1091-1097.
19. Pellinen T, Arjonen A, Vuoriluoto K, Kallio K, Fransen JA, Ivaska J (2006). Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of â1-integrins. J Cell Biol 173, 767-780. (Pubitemid 46165584)
20. Pereira-Leal JB, Seabra MC (2000). The mammalian Rab family of small GTPases: definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily. J Mol Biol 301, 1077-1087.
21. Pereira-Leal JB, Seabra MC (2001). Evolution of the Rab family of small GTP-binding proteins. J Mol Biol 313, 889-901. (Pubitemid 33063434)
22. Pfaffl MW (2001). A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29, e45.
23. Rink J, Ghigo E, Kalaidzidis Y, Zerial M (2005). Rab conversion as a mechanism of progression from early to late endosomes. Cell 122, 735-749. (Pubitemid 41242638)
24. Rodriguez-Gabin AG, Cammer M, Almazan G, Charron M, Larocca JN (2001). Role of rRAB22b, an oligodendrocyte protein, in regulation of transport of vesicles from trans Golgi to endocytic compartments. J Neurosci Res 66, 1149-1160. (Pubitemid 33135601)
25. Saxena S, Bucci C, Weis J, Kruttgen A (2005). The small GTPase Rab7 controls the endosomal trafficking and neuritogenic signaling of the nerve growth factor receptor TrkA. J Neurosci 25, 10930-10940. (Pubitemid 41692623)
26. Simpson JC, Griffiths G, Wessling-Resnick M, Fransen JA, Bennett H, Jones AT (2004). A role for the small GTPase Rab21 in the early endocytic pathway. J Cell Sci 117, 6297-6311. (Pubitemid 40214558)
27. Stenmark H (2009). Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Biol 10, 513-525.
28. Weigert R, Yeung AC, Li J, Donaldson JG (2004). Rab22a regulates the recycling of membrane proteins internalized independently of clathrin. Mol Biol Cell 15, 3758-3770. (Pubitemid 38989713)
29. Zhang Y, Moheban DB, Conway BR, Bhattacharyya A, Segal RA (2000). Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation. J Neurosci 20, 5671-5678. (Pubitemid 30636894)
30. Zhu G et al. (2007). Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5. EMBO J 26, 3484-3493. (Pubitemid 47123536)
31. Zhu H, Liang Z, Li G (2009). Rabex-5 is a Rab22 effector and mediates a Rab22-Rab5 signaling cascade in endocytosis. Mol Biol Cell 20, 4720-4729.