-
1
-
-
0027183870
-
Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer
-
Grandis JR, Tweardy DJ. Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer. Cancer Res 1993;53:3579.
-
(1993)
Cancer Res
, vol.53
, pp. 3579
-
-
Grandis, J.R.1
Tweardy, D.J.2
-
2
-
-
21444436806
-
Expression of EGFR, HER2, HER3, and HER4 in metastatic squamous cell carcinomas of the oral cavity and base of tongue
-
Ekberg T, Nestor M, Engstrom M, et al. Expression of EGFR, HER2, HER3, and HER4 in metastatic squamous cell carcinomas of the oral cavity and base of tongue. Int J Oncol 2005;26:1177.
-
(2005)
Int J Oncol
, vol.26
, pp. 1177
-
-
Ekberg, T.1
Nestor, M.2
Engstrom, M.3
-
3
-
-
20244389231
-
Somatic mutations of EGFR gene in squamous cell carcinoma of the head and neck
-
Lee JW, Soung YH, Kim SY, et al. Somatic mutations of EGFR gene in squamous cell carcinoma of the head and neck. Clin Cancer Res 2005;11:2879.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2879
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, S.Y.3
-
4
-
-
29144520704
-
Low incidence of mutations in EGFR kinase domain in Caucasian patients with head and neck squamous cell carcinoma
-
Loeffler-Ragg J, Witsch-Baumgartner M, Tzankov A, et al. Low incidence of mutations in EGFR kinase domain in Caucasian patients with head and neck squamous cell carcinoma. Eur J Cancer 2006;42:109.
-
(2006)
Eur J Cancer
, vol.42
, pp. 109
-
-
Loeffler-Ragg, J.1
Witsch-Baumgartner, M.2
Tzankov, A.3
-
5
-
-
2342492313
-
Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression
-
DOI 10.1016/S1535-6108(04)00112-6, PII S1535610804001126
-
Chung CH, Parker JS, Karaca G, et al. Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression. Cancer Cell 2004;5:489-500. (Pubitemid 38610250)
-
(2004)
Cancer Cell
, vol.5
, Issue.5
, pp. 489-500
-
-
Chung, C.H.1
Parker, J.S.2
Karaca, G.3
Wu, J.4
Funkhouser, W.K.5
Moore, D.6
Butterfoss, D.7
Xiang, D.8
Zanation, A.9
Yin, X.10
Shockley, W.W.11
Weissler, M.C.12
Dressler, L.G.13
Shores, C.G.14
Yarbrough, W.G.15
Perou, C.M.16
-
6
-
-
0032478998
-
Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival
-
Rubin Grandis J, Melhem MF, Gooding WE, et al. Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst 1998; 90:824.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 824
-
-
Rubin Grandis, J.1
Melhem, M.F.2
Gooding, W.E.3
-
7
-
-
0027432231
-
EGFR and PCNA experession in oral squamous cell carcinomas-a valuable tool in estimating the patient's prognosis
-
Störkel S, Reichert T, Reiffen KA, et al. EGFR and PCNA experession in oral squamous cell carcinomas-a valuable tool in estimating the patient's prognosis. Eur J Cancer Part B: Oral Oncol 1993;29:273.
-
(1993)
Eur J Cancer Part B: Oral Oncol
, vol.29
, pp. 273
-
-
Störkel, S.1
Reichert, T.2
Reiffen, K.A.3
-
8
-
-
34548417668
-
Response to therapy and outcomes in oropharyngeal cancer are associated with bio-markers including human papillomavirus, epidermal growth factor receptor, gender, and smoking
-
Kumar B, Cordell KG, Lee JS, et al. Response to therapy and outcomes in oropharyngeal cancer are associated with bio-markers including human papillomavirus, epidermal growth factor receptor, gender, and smoking. Int J Radiat Oncol Biol Phys 2007;69(2 suppl):S109.
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.69
, Issue.2 SUPPL.
-
-
Kumar, B.1
Cordell, K.G.2
Lee, J.S.3
-
9
-
-
0037115674
-
Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma
-
Ang KK, Berkey BA, Tu X, et al. Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma. Cancer Res 2002;62:7350.
-
(2002)
Cancer Res
, vol.62
, pp. 7350
-
-
Ang, K.K.1
Berkey, B.A.2
Tu, X.3
-
10
-
-
14744285428
-
The influence of epidermal growth factor receptor and tumor differentiation on the response to accelerated radiotherapy of squamous cell carcinomas of the head and neck in the randomized DA-HANCA 6 and 7 study
-
Eriksen JG, Steiniche T, Overgaard J. The influence of epidermal growth factor receptor and tumor differentiation on the response to accelerated radiotherapy of squamous cell carcinomas of the head and neck in the randomized DA-HANCA 6 and 7 study. Radiother Oncol 2005;74:93.
-
(2005)
Radiother Oncol
, vol.74
, pp. 93
-
-
Eriksen, J.G.1
Steiniche, T.2
Overgaard, J.3
-
11
-
-
24944479590
-
Epidermal growth factor receptor expression in pretreatment biopsies from head and neck squamous cell carcinoma as a predictive factor for a benefit from accelerated radiation therapy in a randomized controlled trial
-
Bentzen SM, Atasoy BM, Daley FM, et al. Epidermal growth factor receptor expression in pretreatment biopsies from head and neck squamous cell carcinoma as a predictive factor for a benefit from accelerated radiation therapy in a randomized controlled trial. J Clin Oncol 2005;23:5560.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5560
-
-
Bentzen, S.M.1
Atasoy, B.M.2
Daley, F.M.3
-
12
-
-
77953927395
-
Molecular imaging of HER2-expressing malignant tumors in breast cancer patients using synthetic 111In-or 68Ga-labeled affibody molecules
-
Baum RP, Prasad V, Muller D, et al. Molecular imaging of HER2-expressing malignant tumors in breast cancer patients using synthetic 111In-or 68Ga-labeled affibody molecules. J Nucl Med 2010;51:892.
-
(2010)
J Nucl Med
, vol.51
, pp. 892
-
-
Baum, R.P.1
Prasad, V.2
Muller, D.3
-
13
-
-
0034102191
-
A comparison of EGF and MAb 528 labeled with 111In for imaging human breast cancer
-
Reilly RM, Kiarash R, Sandhu J, et al. A comparison of EGF and MAb 528 labeled with 111In for imaging human breast cancer. J Nucl Med 2000;41:903.
-
(2000)
J Nucl Med
, vol.41
, pp. 903
-
-
Reilly, R.M.1
Kiarash, R.2
Sandhu, J.3
-
14
-
-
0030049664
-
Radiolocalization of squamous lung carcinoma with 131I-labeled epidermal growth factor
-
Cuartero-Plaza A, Martinez-Miralles E, Rosell R, et al. Radiolocalization of squamous lung carcinoma with 131I-labeled epidermal growth factor. Clin Cancer Res 1996;2:13.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 13
-
-
Cuartero-Plaza, A.1
Martinez-Miralles, E.2
Rosell, R.3
-
15
-
-
33644818017
-
Preparation and evaluation of (68)Ga-DOTA-hEGF for visualization of EGFR expression in malignant tumors
-
Velikyan I, Sundberg AL, Lindhe O, et al. Preparation and evaluation of (68)Ga-DOTA-hEGF for visualization of EGFR expression in malignant tumors. J Nucl Med 2005;46:1881.
-
(2005)
J Nucl Med
, vol.46
, pp. 1881
-
-
Velikyan, I.1
Sundberg, A.L.2
Lindhe, O.3
-
16
-
-
77949273331
-
Imaging of EGFR expression in murine xenografts using site-specifically labelled anti-EGFR 111In-DOTA-Z EGFR:2377 Affibody molecule: Aspect of the injected tracer amount
-
Tolmachev V, Rosik D, Wallberg H, et al. Imaging of EGFR expression in murine xenografts using site-specifically labelled anti-EGFR 111In-DOTA-Z EGFR:2377 Affibody molecule: aspect of the injected tracer amount. Eur J Nucl Med Mol Imaging 2010;37:613.
-
(2010)
Eur J Nucl Med Mol Imaging
, vol.37
, pp. 613
-
-
Tolmachev, V.1
Rosik, D.2
Wallberg, H.3
-
17
-
-
0026426157
-
Phase i and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma
-
Divgi CR, Welt S, Kris M, et al. Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma. J Natl Cancer Inst 1991;83:97.
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 97
-
-
Divgi, C.R.1
Welt, S.2
Kris, M.3
-
18
-
-
35848944434
-
Effect of the EGFR density of breast cancer cells on nuclear importation, in vitro cyto-toxicity, and tumor and normal-tissue uptake of [111In]-DTPA-hEGF
-
Hu M, Scollard D, Chan C, et al. Effect of the EGFR density of breast cancer cells on nuclear importation, in vitro cyto-toxicity, and tumor and normal-tissue uptake of [111In]-DTPA-hEGF. Nucl Med Biol 2007;34:887.
-
(2007)
Nucl Med Biol
, vol.34
, pp. 887
-
-
Hu, M.1
Scollard, D.2
Chan, C.3
-
19
-
-
77951252397
-
Blocking EGFR in the liver improves the tumor-to-liver uptake ratio of radio-labeled EGF
-
Kareem H, Sandstrom K, Elia R, et al. Blocking EGFR in the liver improves the tumor-to-liver uptake ratio of radio-labeled EGF. Tumour Biol 2010;31:79.
-
(2010)
Tumour Biol
, vol.31
, pp. 79
-
-
Kareem, H.1
Sandstrom, K.2
Elia, R.3
-
20
-
-
4644325597
-
Comparative biodis-tribution of potential anti-glioblastoma conjugates [111In]-DTPA-hEGF and [111In]Bz-DTPA-hEGF in normal mice
-
Tolmachev V, Orlova A, Wei Q, et al. Comparative biodis-tribution of potential anti-glioblastoma conjugates [111In]-DTPA-hEGF and [111In]Bz-DTPA-hEGF in normal mice. Cancer Biother Radiopharm 2004;19:491.
-
(2004)
Cancer Biother Radiopharm
, vol.19
, pp. 491
-
-
Tolmachev, V.1
Orlova, A.2
Wei, Q.3
-
21
-
-
0028982245
-
A combinatorial library of an alpha-helical bacterial receptor domain
-
Nord K, Nilsson J, Nilsson B, et al. A combinatorial library of an alpha-helical bacterial receptor domain. Protein Eng 1995;8:601.
-
(1995)
Protein Eng
, vol.8
, pp. 601
-
-
Nord, K.1
Nilsson, J.2
Nilsson, B.3
-
22
-
-
77953130101
-
Affibody molecules: Engineered proteins for therapeutic, diagnostic and biotechnological applications
-
Lofblom J, Feldwisch J, Tolmachev V, et al. Affibody molecules: engineered proteins for therapeutic, diagnostic and biotechnological applications. FEBS Lett 2010;584:2670.
-
(2010)
FEBS Lett
, vol.584
, pp. 2670
-
-
Lofblom, J.1
Feldwisch, J.2
Tolmachev, V.3
-
23
-
-
43849098417
-
2, in EGFR expressing tumour cells
-
Nordberg E, Orlova A, Friedman M, et al. In vivo and in vitro uptake of 111In, delivered with the affibody molecule (ZEGFR:955)2, in EGFR expressing tumour cells. Oncol Rep 2008;19:853-857. (Pubitemid 351802651)
-
(2008)
Oncology Reports
, vol.19
, Issue.4
, pp. 853-857
-
-
Nordberg, E.1
Orlova, A.2
Friedman, M.3
Tolmachev, V.4
Stahl, S.5
Nilsson, F.Y.6
Glimelius, B.7
Carlsson, J.8
-
24
-
-
59249088447
-
Affibody molecules for epidermal growth factor receptor targeting in vivo: Aspects of dimerization and labeling chemistry
-
Tolmachev V, Friedman M, Sandstrom M, et al. Affibody molecules for epidermal growth factor receptor targeting in vivo: aspects of dimerization and labeling chemistry. J Nucl Med 2009;50:274.
-
(2009)
J Nucl Med
, vol.50
, pp. 274
-
-
Tolmachev, V.1
Friedman, M.2
Sandstrom, M.3
-
25
-
-
65249120736
-
SPECT and PET imaging of EGF receptors with site-specifically labeled EGF and dimeric EGF
-
Levashova Z, Backer MV, Horng G, et al. SPECT and PET imaging of EGF receptors with site-specifically labeled EGF and dimeric EGF. Bioconjug Chem 2009;20:742.
-
(2009)
Bioconjug Chem
, vol.20
, pp. 742
-
-
Levashova, Z.1
Backer, M.V.2
Horng, G.3
-
26
-
-
77950297123
-
In vivo binding of [68Ga]-DOTATOC to somatostatin receptors in neuroendo-crine tumours-impact of peptide mass
-
Velikyan I, Sundin A, Eriksson B, et al. In vivo binding of [68Ga]-DOTATOC to somatostatin receptors in neuroendo-crine tumours-impact of peptide mass. Nucl Med Biol 2010;37:265.
-
(2010)
Nucl Med Biol
, vol.37
, pp. 265
-
-
Velikyan, I.1
Sundin, A.2
Eriksson, B.3
-
27
-
-
39749104116
-
Convenient preparation of 68Ga-based PET-radiopharmaceuticals at room temperature
-
Velikyan I, Maecke H, Langstrom B. Convenient preparation of 68Ga-based PET-radiopharmaceuticals at room temperature. Bioconjug Chem 2008;19:569.
-
(2008)
Bioconjug Chem
, vol.19
, pp. 569
-
-
Velikyan, I.1
Maecke, H.2
Langstrom, B.3
-
28
-
-
34347380371
-
Phage display selection of Affibody molecules with specific binding to the extracellular domain of the epidermal growth factor receptor
-
Friedman M, Nordberg E, Hoiden-Guthenberg I, et al. Phage display selection of Affibody molecules with specific binding to the extracellular domain of the epidermal growth factor receptor. Protein Eng Des Sel 2007;20:189.
-
(2007)
Protein Eng des Sel
, vol.20
, pp. 189
-
-
Friedman, M.1
Nordberg, E.2
Hoiden-Guthenberg, I.3
-
29
-
-
39149087035
-
Directed evolution to low nanomolar affinity of a tumor-targeting epidermal growth factor receptor-binding affibody molecule
-
Friedman M, Orlova A, Johansson E, et al. Directed evolution to low nanomolar affinity of a tumor-targeting epidermal growth factor receptor-binding affibody molecule. J Mol Biol 2008;376:1388.
-
(2008)
J Mol Biol
, vol.376
, pp. 1388
-
-
Friedman, M.1
Orlova, A.2
Johansson, E.3
-
30
-
-
45449120466
-
The importance of high specific radioactivity in the performance of (68)Ga-labeled peptide
-
Velikyan I, Beyer GJ, Bergstrom-Pettermann E, et al. The importance of high specific radioactivity in the performance of (68)Ga-labeled peptide. Nucl Med Biol 2008; 35:529.
-
(2008)
Nucl Med Biol
, vol.35
, pp. 529
-
-
Velikyan, I.1
Beyer, G.J.2
Bergstrom-Pettermann, E.3
-
31
-
-
34547830391
-
Cellular studies of binding, internalization and retention of a radiolabeled EGFR-binding affibody molecule
-
Nordberg E, Friedman M, Gostring L, et al. Cellular studies of binding, internalization and retention of a radiolabeled EGFR-binding affibody molecule. Nucl Med Biol 2007; 34:609.
-
(2007)
Nucl Med Biol
, vol.34
, pp. 609
-
-
Nordberg, E.1
Friedman, M.2
Gostring, L.3
-
32
-
-
77749299225
-
Effects of an EGFR-binding affibody molecule on intracellular signaling pathways
-
Nordberg E, Ekerljung L, Sahlberg SH, et al. Effects of an EGFR-binding affibody molecule on intracellular signaling pathways. Int J Oncol 2010;36:967.
-
(2010)
Int J Oncol
, vol.36
, pp. 967
-
-
Nordberg, E.1
Ekerljung, L.2
Sahlberg, S.H.3
-
33
-
-
77749333043
-
Quantification of internalization of EGFR-binding Affibody molecules: Methodological aspects
-
Gostring L, Chew MT, Orlova A, et al. Quantification of internalization of EGFR-binding Affibody molecules: Methodological aspects. Int J Oncol 2010;36:757.
-
(2010)
Int J Oncol
, vol.36
, pp. 757
-
-
Gostring, L.1
Chew, M.T.2
Orlova, A.3
|