The CXCR4-CXCL12 pathway facilitates the progression of pancreatic cancer via induction of angiogenesis and lymphangiogenesis

Journal of Surgical Research

Volumn 171, Issue 1, 2011, Pages 143-150

  Cui, Kai ^a   Zhao, Wenhua ^b   Wang, Changliang ^a   Wang, Ailiang ^c   Zhang, Bo ^a   Zhou, Wuyuan ^a   Yu, Jinming ^a   Sun, Ziqiang ^c   Li, Sheng ^a  

^a SHANDONG CANCER HOSPITAL AND INSTITUTE   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^c Affiliated Hospital of ji'Ning Medical College   (China)

Author keywords

angiogenesis; chemokine receptors; chemokines; lymphangiogenesis; pancreatic neoplasms

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; STROMAL CELL DERIVED FACTOR 1;

ANGIOGENESIS; ARTICLE; CANCER GROWTH; CANCER TISSUE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE; LYMPH NODE METASTASIS; LYMPH VESSEL; LYMPHANGIOGENESIS; MICROVASCULATURE; PANCREAS; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ADULT; AGED; CHEMOKINE CXCL12; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LYMPHANGIOGENESIS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM GRADING; NEOPLASM STAGING; NEOVASCULARIZATION, PATHOLOGIC; PANCREATIC NEOPLASMS; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION;

EID: 80054697462     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2010.03.001     Document Type: Article

References (48)

1. A. Jemal, R. Siegel, and E. Ward Cancer statistics, 2009 CA Cancer J Clin 59 2009 225
2. A. Jemal, T. Murray, and A. Samuels Cancer statistics, 2003 CA Cancer J Clin 53 2003 5
3. T.A. Sohn, and C.J. Yeo The molecular genetics of pancreatic ductal carcinoma: A review Surg Oncol 9 2000 95
4. I.J. Fidler, and I.R. Hart Biological diversity in metastatic neoplasms: Origins and implications Science 217 1982 998
5. L.A. Liotta An attractive force in metastasis Nature 410 2001 24
6. L.A. Liotta, M.G. Saidel, and J. Kleinerman The significance of hematogenous tumor cell clumps in the metastatic process Cancer Res 36 1976 889
7. G.L. Nicolson Molecular mechanisms of cancer metastasis: Tumor and host properties and the role of oncogenes and suppressor genes Curr Opin Oncol 3 1991 75
8. A.F. Chambers, A.C. Groom, and I.C. MacDonald Dissemination and growth of cancer cells in metastatic sites Nat Rev Cancer 2 2002 563
9. M. Baggiolini, B. Dewald, and B. Moser Human chemokines: An update Annu Rev Immunol 15 1997 675
10. S. Jung, and D.R. Littman Chemokine receptors in lymphoid organ homeostasis Curr Opin Immunol 11 1999 319
11. L. Xu, Y. Zhou, and Q. Liu CXCR4/SDF-1 pathway is crucial for TLR9 agonist enhanced metastasis of human lung cancer cell Biochem Biophys Res Commun 382 2009 571
12. B. Bottazzi, S. Walter, and D. Govoni Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth, and susceptibility to IL-2 therapy of a murine melanoma J Immunol 148 1992 1280
13. S. Miwa, A. Mizokami, and E.T. Keller The bisphosphonate YM529 inhibits osteolytic and osteoblastic changes and CXCR-4-induced invasion in prostate cancer Cancer Res 65 2005 8818
14. F. Sallusto, P. Schaerli, and P. Loetscher Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation Eur J Immunol 28 1998 2760
15. S. Sozzani, P. Allavena, and G. D'Amico Differential regulation of chemokine receptors during dendritic cell maturation: A model for their trafficking properties J Immunol 161 1998 1083
16. M.C. Dieu, B. Vanbervliet, and A. Vicari Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites J Exp Med 188 1998 373
17. M. Monterrubio, M. Mellado, and A.C. Carrera PI3Kgamma activation by CXCL12 regulates tumor cell adhesion and invasion Biochem Biophys Res Commun 388 2009 199
18. A. Ricciardi, A.R. Elia, and P. Cappello Transcriptome of hypoxic immature dendritic cells: Modulation of chemokine/receptor expression Mol Cancer Res 6 2008 175
19. D. Uchida, T. Onoue, and N.M. Begum Vesnarinone downregulates CXCR4 expression via upregulation of Kruppel-like factor 2 in oral cancer cells Mol Cancer 8 2009 62
20. A. Muller, B. Homey, and H. Soto Involvement of chemokine receptors in breast cancer metastasis Nature 410 2001 50
21. K. Sasaki, S. Natsugoe, and S. Ishigami Expression of CXCL12 and its receptor CXCR4 in esophageal squamous cell carcinoma Oncol Rep 21 2009 65
22. K.L. Reckamp, R.A. Figlin, and M.D. Burdick CXCR4 expression on circulating pan-cytokeratin positive cells is associated with survival in patients with advanced non-small cell lung cancer BMC Cancer 9 2009 213
23. Y. Yoon, Z. Liang, and X. Zhang CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models Cancer Res 67 2007 7518
24. C.T. Tan, C.Y. Chu, and Y.C. Lu CXCL12/CXCR4 promotes laryngeal and hypopharyngeal squamous cell carcinoma metastasis through MMP-13-dependent invasion via the ERK1/2/AP-1 pathway Carcinogenesis 29 2008 1519
25. J. Morales, B. Homey, and A.P. Vicari CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells Proc Natl Acad Sci USA 96 1999 14470
26. A. Zlotnik, and O. Yoshie Chemokines: A new classification system and their role in immunity Immunity 12 2000 121
27. J.J. Campbell, and E.C. Butcher Chemokines in tissue-specific and microenvironment-specific lymphocyte homing Curr Opin Immunol 12 2000 336
28. E.C. Butcher, M. Williams, and K. Youngman Lymphocyte trafficking and regional immunity Adv Immunol 72 1999 209
29. R.S. Klein, J.B. Rubin, and H.D. Gibson SDF-1 alpha induces chemotaxis and enhances Sonic hedgehog-induced proliferation of cerebellar granule cells Development 128 2001 1971
30. A. Peled, I. Petit, and O. Kollet Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4 Science 283 1999 845
31. J.W. Oh, M. Olman, and E.N. Benveniste CXCL12-mediated induction of plasminogen activator inhibitor-1 expression in human CXCR4 positive astroglioma cells Biol Pharm Bull 32 2009 573
32. F. Sallusto, C.R. Mackay, and A. Lanzavecchia The role of chemokine receptors in primary, effector, and memory immune responses Annu Rev Immunol 18 2000 593
33. M.C. Ghosh, G.D. Collins, and B. Vandanmagsar Activation of Wnt5A signaling is required for CXC chemokine ligand 12-mediated T-cell migration Blood 114 2009 1366
34. K.J. Eash, J.M. Means, and D.W. White CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions Blood 113 2009 4711
35. L. Salogni, T. Musso, and D. Bosisio Activin A induces dendritic cell migration through the polarized release of CXC chemokine ligands 12 and 14 Blood 113 2009 5848
36. K.S. Seo, J.Y. Park, and W.C. Davis Superantigen-mediated differentiation of bovine monocytes into dendritic cells J Leukoc Biol 85 2009 606
37. Q. Leng, Y. Nie, and Y. Zou Elevated CXCL12 expression in the bone marrow of NOD mice is associated with altered T cell and stem cell trafficking and diabetes development BMC Immunol 9 2008 51
38. Q. Xu, X. Yuan, and M. Xu Chemokine CXC receptor 4-mediated glioma tumor tracking by bone marrow-derived neural progenitor/stem cells Mol Cancer Ther 8 2009 2746
39. V. Mirisola, A. Zuccarino, and B.E. Bachmeier CXCL12/SDF1 expression by breast cancers is an independent prognostic marker of disease-free and overall survival Eur J Cancer 45 2009 2579
40. A. Salmaggi, E. Maderna, and C. Calatozzolo CXCL12, CXCR4 and CXCR7 expression in brain metastases Cancer Biol Ther 8 2009 1608
41. S. Hassan, C. Ferrario, and U. Saragovi The influence of tumor-host interactions in the stromal cell-derived factor-1/CXCR4 ligand/receptor axis in determining metastatic risk in breast cancer Am J Pathol 175 2009 66
42. D.R. Welch, and S.F. Goldberg Molecular mechanisms controlling human melanoma progression and metastasis Pathobiology 65 1997 311
43. E.R. Sauter, and M. Herlyn Molecular biology of human melanoma development and progression Mol Carcinog 23 1998 132
44. C. Lu, and R.S. Kerbel Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression J Cell Biol 120 1993 1281
45. X. Wu, V.C. Lee, and E. Chevalier Chemokine receptors as targets for cancer therapy Curr Pharm Des 15 2009 742
46. J. Vandercappellen, J. Van Damme, and S. Struyf The role of CXC chemokines and their receptors in cancer Cancer Lett 267 2008 226
47. M.K. Wendt, P.A. Johanesen, and N. Kang-Decker Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis Oncogene 25 2006 4986
48. M. Kucia, K. Jankowski, and R. Reca CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion J Mol Histol 35 2004 233