Mucoadhesive platforms for targeted delivery to the colon

International Journal of Pharmaceutics

Volumn 420, Issue 1, 2011, Pages 11-19

  Varum, Felipe J O ^a,b   Veiga, Francisco ^a   Sousa, João S ^a   Basit, Abdul W ^b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Carbomers; Colonic delivery; Enteric coatings; Large intestine; Methacrylic acid and methyl methacrylate; Mucoadhesion; Multiparticulates; pH sensitive polymers; Transit time

Indexed keywords

BICARBONATE; CARBOPOL 971P; CARBOPOL 974P; EUDRAGIT; FLUORESCENT DYE; HYDROCHLORIC ACID; POLYCARBOPHIL; POLYMER; PREDNISOLONE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; COLON; COLON MUCOSA; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PELLET; DRUG RELEASE; DRUG SOLUBILITY; ENTERIC COATED TABLET; EX VIVO STUDY; GASTROINTESTINAL TRANSIT; IN VITRO STUDY; MUCOADHESION; NONHUMAN; PELLET EXTRUSION; PH; PRIORITY JOURNAL; SPHERONIZATION; SWINE;

ACRYLATES; ACRYLIC RESINS; ADHESIVENESS; ADMINISTRATION, ORAL; ANIMALS; CHEMISTRY, PHARMACEUTICAL; COLON; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG COMPOUNDING; GASTROINTESTINAL AGENTS; HYDROGEN-ION CONCENTRATION; INTESTINAL MUCOSA; KINETICS; MICROSCOPY, CONFOCAL; MODELS, CHEMICAL; POLYMETHACRYLIC ACIDS; PREDNISOLONE; SOLUBILITY; SWINE; TABLETS, ENTERIC-COATED; TECHNOLOGY, PHARMACEUTICAL;

EID: 80054695443     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.08.006     Document Type: Article

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