Extrusion-spheronization of blends of Carbopol 934 and microcrystalline cellulose

Drug Development and Industrial Pharmacy

Volumn 27, Issue 5, 2001, Pages 381-391

  Gomez Carracedo A ^a   Alvarez Lorenzo, C ^a   Gomez Amoza J L ^a   Martinez Pacheco R ^a   Souto, C ^a   Concheiro, A ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Carbopol 934; Extrusion spheronization; Microcrystalline cellulose; Mixer torque rheometry; Pellets; Theophylline

Indexed keywords

CALCIUM CHLORIDE; CARBOPOL 934; MICROCRYSTALLINE CELLULOSE; THEOPHYLLINE;

ARTICLE; DRUG FORMULATION; DRUG RELEASE; HYDRATION; PARTICLE SIZE; PELLET EXTRUSION; SPHERONIZATION; TABLET; TORQUE;

ACRYLATES; ALGORITHMS; CELLULOSE; DELAYED-ACTION PREPARATIONS; DRUG DESIGN; PARTICLE SIZE; STRUCTURE-ACTIVITY RELATIONSHIP; TABLETS; THEOPHYLLINE;

EID: 0034957723     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.1081/DDC-100104313     Document Type: Article

References (32)

1. Key factors in the development of modified-release pellets
2. Aspects of viscometry. The measurement of the elastic behaviour of visco-elastic fluids
3. Multiple linear regression
4. Extrusion/spheronisation