Uptake of 3-[125I]iodo-α-methyl-l-tyrosine into colon cancer DLD-1 cells: characterization and inhibitory effect of natural amino acids and amino acid-like drugs

Nuclear Medicine and Biology

Volumn 37, Issue 2, 2010, Pages 197-204

  Shikano, Naoto ^a   Ogura, Masato ^a   Okudaira, Hiroyuki ^b   Nakajima, Syuichi ^a   Kotani, Takashi ^a   Kobayashi, Masato ^b   Nakazawa, Shinya ^a   Baba, Takeshi ^a   Yamaguchi, Naoto ^a   Kubota, Nobuo ^a   Iwamura, Yukio ^a   Kawai, Keiichi ^b  

^a IBARAKI PREFECTURAL UNIVERSITY OF HEALTH SCIENCES   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

3 Iodo methyl l tyrosine; Amino acid like drug; Colon cancer cell line; DLD 1; Inhibitor; l Type amino acid tranasporter 1

Indexed keywords

3 IODO METIROSINE I 123; AMINO ACID DERIVATIVE; AMINO ACID TRANSPORTER; BACLOFEN; BUFFER; CYSTEINE; GABAPENTIN; LEVODOPA; METIROSINE METHYL ESTER; PHENYLALANINE DERIVATIVE; RADIOISOTOPE; SERINE; THREO 3,4 DIHYDROXYPHENYLSERINE; TRYPTOPHAN DERIVATIVE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG; 3 IODO ALPHA METHYLTYROSINE; 3-IODO-ALPHA-METHYLTYROSINE; AMINO ACID; METIROSINE;

AMINO ACID TRANSPORT; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG TRANSPORT; DRUG UPTAKE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HYDROXYLATION; MICHAELIS MENTEN KINETICS; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; CHEMISTRY; COLON TUMOR; GENETICS; METABOLISM; PATHOLOGY; STRUCTURE ACTIVITY RELATION; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

AMINO ACID TRANSPORT SYSTEMS; AMINO ACIDS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; COLONIC NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; METHYLTYROSINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 76949084253     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2009.10.011     Document Type: Article

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