In vitro and in vivo iontophoretic transdermal delivery of an anti-parkinsonian agent

International Journal of Pharmaceutics

Volumn 420, Issue 1, 2011, Pages 20-25

  Vemulapalli, V ^a   Yang, Y ^a   Siddoju, S ^a   Conjeevaram, R ^b   Teunissen, H ^b   Myers, T ^b   Banga, A K ^a  

^a MERCER UNIVERSITY   (United States)

^b Solvay Pharmaceuticals Inc   (Netherlands)

Author keywords

Counter ions; Iontophoresis; Parkinson's; Pharmacokinetics; SLV 318; Transdermal

Indexed keywords

ANTIPARKINSON AGENT; COUNTERION; SLV 318; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG SOLUBILITY; FEASIBILITY STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; ION SELECTIVE ELECTRODE; IONTOPHORESIS; LIQUID CHROMATOGRAPHY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN PENETRATION; SKIN TEMPERATURE; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIPARKINSON AGENTS; BENZOXAZOLES; BUFFERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEASIBILITY STUDIES; HYDROGEN-ION CONCENTRATION; IONTOPHORESIS; MESYLATES; PERMEABILITY; PIPERAZINES; RATS; RATS, HAIRLESS; SKIN; SKIN ABSORPTION; SOLUBILITY; TANDEM MASS SPECTROMETRY; TEMPERATURE;

EID: 80054693906     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.08.013     Document Type: Article

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